个人简介

学习、工作经历： 2018.7-至今郑州大学，基础医学院，病理生理学系，讲师 2014.9-2018.6湖南大学，化学化工学院，化学，博士 2012.9-2014.6湖南大学，生物学院，生物学，硕士 2008.9-2012.6周口师范学院，生命科学系，生物技术，学士 教学承担： 五年制、研究生《病理生理学》课程

研究领域

研究方向：生物分析化学

研究方向与特色： 生物分析化学。目前主要开展肿瘤细胞核酸适配体的筛选，基于核酸适配体识别的肿瘤细胞早期检测及肿瘤细胞表面糖蛋白分子成像等工作。 主持项目： 郑州大学青年教师科研启动费（拔尖）项目，编号：32211164，基于核酸适配体-DNA的荧光激活式策略用于肿瘤RTK糖基化检测，2019/01-2020/12，20万元。

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.BaoyinYuan,YuqiongSun,QiupingGuo,*JinHuang,XiaohaiYang,YuanyuanChen,XiaohongWen,XiangxianMeng,JianboLiu,KeminWang*.Highsignal-to-backgroundratiodetectionofcancercellswithactivatablestrategybasedontarget-inducedself-assemblyofsplitaptamers.Anal.Chem.,2017,89,9347−9353. 2.BaoyinYuan,YuanyuanChen,YuqiongSun,QiupingGuo,*JinHuang,JianboLiu,XiangxianMeng,XiaohaiYang,XiaohongWen,ZenghuiLi,LieLi,KeminWang.*Enhancedimagingofspecificcell-surfaceglycosylationbasedonmulti-FRET.Anal.Chem.,2018,90(10):6131-6137. 3.BaoyinYuan,‡YuZhou,‡QiupingGuo,*KeminWang,*XiaohaiYang,XiangxianMeng,JunWan,YuyuTan,ZhixiangHuang,QinXieandXiayuZhao.Asignal-onsplitaptasensorforhighlysensitiveandspecificdetectionoftumorcellsbasedonFRET.Chem.Commun.,2016,52,1590-1593. 4.BaoyinYuan,‡XiaochunJiang,‡YuanyuanChen,QiupingGuo,*KeminWang,*XiangxianMeng,ZhixiangHuang,XiaohongWen.Metastaticcancercellandtissue-specificfluorescenceimagingusinganewDNAaptamerdevelopedbyCell-SELEX.Talanta,2017,170,56-62. 5.XiaohongWen‡,BaoyinYuan‡,JunxunZhang,XiangxianMeng,QiupingGuo,*LieLi,ZenghuiLi,HuishanJiangandKeminWang*.Enhancedvisualizationofcellsurfaceglycansviaahybridizationchainreaction.Chem.Commun.,2019,55,6114—6117. 6.YuqiongSun,‡BaoyinYuan,‡MeitaoDeng,QingWang,JinHuang,QiupingGuo,JianboLiu,XiaohaiYang,*KeminWang.*Alight-upfluorescenceassayfortumorcelldetectionbasedonbifunctionalsplitaptamers.Analyst,2018,143(15),3579-3585. 7.YuyuTan,‡QiupingGuo,‡QinXie,KeminWang,*BaoyinYuan,YuZhou,JianboLiu,JinHuang,XiaoxiaoHe,XiaohaiYang,ChunmeiHe,XiayuZhao.Single-walledcarbonnanotubes(SWCNTs)-assistedcell-systematicevolutionofligandsbyexponentialenrichment(Cell-SELEX)forimprovingscreeningefficiency.Anal.Chem.,2014,86,9466-9472. 8.TaipingQing,XiaoxiaoHe,*DinggengHe,XiaoshengYe,JingfangShangguan,JinquanLiu,BaoyinYuan,KeminWang.*DumbbellDNA-templatedCuNPsasanano-fluorescentprobefordetectionofenzymesinvolvedinligase-mediatedDNArepair.Biosens.Bioelectron.,2017,94,456-46. 9.JunWan,‡LingYe,‡XiaohaiYang,QiupingGuo,*KeminWang,*ZhixiangHuang,YuyuTan,BaoyinYuan,QinXie.Cell-SELEXbasedselectionandoptimizationofDNAaptamersforspecificrecognitionofhumancholangiocarcinomaQBC-939cells.Analyst,2015,140,5992-5997. 10.QinXie,‡YuyuTan,‡QiupingGuo,*KeminWang,*BaoyinYuan,JunWan,XiayuZhao.AfluorescentaptasensorforsensitivedetectionofhumanhepatocellularcarcinomaSMMC-7721cellsbasedongrapheneoxide.Anal.Methods,2014,6,6809-6814. 11.ZhixiangHuang,QinXie,QiupingGuo*,KeminWang*,XiangxianMeng,BaoyinYuan,JunWan,YuanyuanChen.DNAaptamerselectedforspecificrecognitionofprostatecancercellsandclinicaltissues.ChineseChemicalLetters,2017,28,1252-1257. QiupingGuo,XiayuZhao,QinXie,KeminWang,*JunWan,BaoyinYuan,YuyuTan.Label-freefluorescencesignalamplifyingdetectionofDNAbasedonhairpinprobeandExoIII.Chem.JChineseU,2014,35,1646-1651.