个人简介
B.S., Humboldt State University, 1982
Ph.D., Cornell University, 1988
Postdoctorate, Massachusetts Institute of Technology and University of California, Santa Barbara, 1988-1992
近期论文
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Maruthamuthu V, Schulten K, Leckband D. Elasticity and Rupture of a Multi-domain NCAM Complex. Biophys J. 2009, In press.
Shi Q, Chien YH, Leckband D. Biophysical properties of cadherin bonds do not predict cell sorting. J Biol Chem. 2008 Vol. 283, Issue 42, 28454-28463.
Leckband D. Beyond structure: mechanism and dynamics of intercellular adhesion. Biochem Soc Trans. 2008 Apr;36(Pt 2):213-20.
Chien YH, Jiang N, Li F, Zhang F, Zhu C, Leckband D. Two stage cadherin kinetics require multiple extracellular domains but not the cytoplasmic region. J Biol Chem. 2008 Jan 25;283(4):1848-56.
Zhu, X., Yan, C., Winnik, F.M., Leckband, D.E. End-Grafted Low Molecular Weight PNIPAM Does Not Collapse above the LCST, Langmuir. 2007 23(1):162-9
R. Dong, T.W. Jensen, R.G. Nuzzo, D.E. Leckband, "Variably elastic hydrogel patterned via capillary action in micro channels," Langmuir, 23, 1483-1488 (2007).
M.V. Bayas, A. Kearney, A. Avramovic, P.A. van der Merwe and D.E. Leckband, "Impact of salt bridges on the equilibrium binding and adhesion of human CD2 and CD58," J. Biol.l Chem., 282, 5589-5596 (2007).
A.K. Prakasam, V. Maruthamuthu and D.E. Leckband, "Similarities between heterophilic and homophilic cadherin adhesion," Proc. Nat. Acad. Sci. USA, 103, 15434-15439 (2006).
A. Prakasam, Y.H. Chien, V. Maruthamuthu and D.E. Leckband, "Calcium site mutations in cadherin: Impact on adhesion and evidence of cooperativity," Biochemistry, 45, 6930-6939 (2006).
X. Zhu, C. Yan, F.M. Winnik, D.E. Leckband, "End-grafted low molecular weight PNIPAM does not collapse above the LCST, Langmuir, (2007, in ASAP).
S.C. Wuang, K.G. Neoh, E.T. Kang, D.W. Pack and D.E. Leckband, "Heparinized magnetic nanoparticles: In-vitro assessment for biomedical applications," Adv. Functional Materials, 16, 1723-1730 (2006).
R.C. Gunawan, J. Silvestre, H.R. Gaskins, P.J.A. Kenis and D.E. Leckband, "Cell migration and polarity on microfabricated gradients of extracellular matrix proteins," Langmuir, 22, 4250-4258 (2006).
K.N. Plunkett, X. Zhu, J.S. Moore and D.E. Leckband, "PNIPAM chain collapse depends on the molecular weight and grafting density," Langmuir, 22, 4259-4266 (2006).
M. Bayas, A. Leung, E. Evans, D. Leckband, Lifetime measurements reveal kinetic differences between homophilic cadherin bonds, Biophys. J., 90, 1385-1395 (2006).
C. Yan, W. Matsuda, D.R. Pepperberg, S.C. Zimmerman and D.E. Leckband, "Synthesis and characterization of an electroactive surface that releases γ-aminobutyric acid (GABA)," J. Coll. Int. Sci., 296, 165-177 (2006).