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个人简介

作为主要完成人参与多项国家自然科学基金(No. 31300884,No. 81271476)的研究工作。已在Angew. Chem. Int. Ed., Adv. Mater, Biomaterials,Chem. Commun, Sensors and Actuators B, J. Mater. Chem. B, Mol Ther Nucleic Acids等国内外学术期刊发表17篇学术论文。其中SCI一区论文8篇、二区论文5篇、3区论文2篇,累计影响因子116分。获批河南省科技厅科技攻关项目2项、河南省教育厅重点科研项目1项、河南大学交叉学科专项项目1项、河南省博士后项目1项。 承担的研究项目: 1.河南省科技发展计划项目,集光动/光热/化疗于一体的苝酰亚胺衍生物的构建及其抗肺癌性能,202102310161,2020.1-2022.12, 10万元,在研,主持。 2.河南省高等学校重点科研项目,酶/pH双响应性光治疗平台的构建及其抗肺癌机制研究,20A310005,2020.1-2021.12, 3万元,在研,主持。 3.河南省科技发展计划项目,162102310074,脑靶向智能响应型纳米药物双载姜黄素和siRNA治疗阿尔茨海默病的探索,2015/12/31-2017/12/31,10万元,已结项,主持人 4.河南省博士后科研项目资助证书三等资助,001703057,多功能苝酰亚胺类载体构建及在阿尔茨海默病的应用,2017/11/08-2019/11/08,5万元,主持 5.河南大学科研基金项目,xxjc20140019,量子点氧化石墨烯双载药系统靶向STAT3治疗胶质母细胞瘤的实验研究,2014/04/20-2019/04/20, 25万元,在研,主持 6.国家自然科学基金,21572045,手性烷基链调控下的苝酰亚胺衍生物自组装结构气敏传感性能研究,2016.01-2019.12,78万,在研,第一参与人 7.国家自然科学基金,31300884,生长抑素受体4与NF-κB通路在小鼠视网膜缺血/再灌注损伤中的作用研究,2014-2016年,结项,第二参与人

研究领域

新型智能响应性载体和新型苝酰亚胺衍生物在肿瘤治疗中的应用。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Rijie Zheng, Qi Zhao, Weixia Qing, Shengliang Li, Zhonghua Liu*, Qianqian Li, and Yongwei Huang*.Carrier-Free Delivery of Ultra-small π-Conjugated Oligomer Nanoparticles with Photothermal Conversion over 80% for Cancer Theranostics. Small . 2021, 18, 2104521 (SCI 一区,IF = 13.3) Zhonghua Liu, Xuejuan Wang, Qing Chen, Feiyan Ma, Yongwei Huang*, Yijian Gao, Qingyuan Deng, Zeng-Ying Qiao*. Xiaoyi Xing, Jianling Zhu, Feng Lu*, Hao Wang*. Regulating Twisted Skeleton to Construct Organ-Specific Perylene for Intensive Cancer Chemotherapy. Angew. Chem. Int. Ed. 2021. 60(29),16215. (SCI 一区,IF = 15.33) Shengliang Li,† Qingyuan Deng,† Xiao Li, Yongwei Huang,* Fang Liu, Huijuan Wang, Weixia Qing, Zhonghua Liu,* and Chun-Sing Lee*,Bis-Diketopyrrolopyrrole Conjugated Polymer Nanoparticles as Photothermic Nanoagonist for Specific and Synergistic Glioblastoma Therapy, Biomaterials, 2019, (216), 119252. (SCI 一区,IF = 12.3) Qing, Weixia; Xing, Xiaoyi; Feng, Dengfeng; Chen, Ruilian; Liu, Zhonghua*, Indocyanine green loaded pH-responsive bortezomib supramolecular hydrogel for synergistic chemo-photothermal/photodynamic colorectal cancer therapy, Photodiagnosis and Photodynamic Therapy, 2021, 36: 102521. (SCI 三区,IF = 3.63) Xin Jin, Xiaoyi xing, Qingyuan Deng, Weixia Qing,* Zhonghua Liu* and Yongwei Huang. Molecular engineering of diketopyrrolopyrrole conjugated polymer nanoparticles by chalcogenide variation for photoacoustic imaging-guided photothermal therapy. J. Mater. Chem. B. 2021, (9), 3153-3160. (SCI 二区,IF = 6.33) Zhonghua Liu, Yijian Gao, Xin Jin, Qingyuan Deng, Zengle Yin, Shuaihang Tong, Weixia Qing* and Yongwei Huang,* Regioisomer-manipulating thio-perylenediimide nanoagents for photothermal/photodynamic theranostics, J. Mater. Chem. B. 2020, (8), 5535-5544. (SCI 二区,IF = 6.33) Qingyuan Deng, Enbao Zhou, Yongwei Huang,* Weixia Qing, Haiyan Zhai, Zhonghua Liu,* and Zhixiang Wei,* Chalcogen−substitution modulated supramolecular chirality and gas sensing properties in perylenediimides, Chem. Commun., 2019, 55(30):4379-4382. (SCI一区,IF = 6.36). Zhonghua Liu, Fang Liu, Yijian Gao, Weixia Qing, Yongwei Huang,*,Shengliang Li,*,and Dongzhu Jin. AIEgen Nanoparticles of Arylamino Fumaronitrile Derivative with High Near-Infrared Emission for Two-Photon Imaging and in Vivo Cell Tracking. ACS Appl. Bio Mater. 2019, (2), 1, 430-436

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