李霞 - 河南大学 - 基础医学院

个人简介

2006年7月毕业于河南大学医学院，获临床医学专业医学学士学位；2009年7月毕业于河南大学医学院，获免疫学专业医学硕士学位；2014年7月毕业于浙江大学医学院，获免疫学专业医学博士学位；2014年10月至2016年10月在北京协和医学院做博士后合作研究。获奖情况李霞，“第六届中国免疫学会青年学者奖”，中国免疫学会，2016年

研究领域

天然免疫应答的表观遗传调控研究、糖代谢在感染性疾病中的调控机制研究及原发肿瘤和肿瘤转移前微环境的相互作用调控机制研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1]Li X,Zhang Q,Ding Y,Liu Y,Zhao D,Zhao K,Shen Q, Liu X, Zhu X, Li N, Cheng Z, Fan G, Wang Q, Cao X. Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate TBK1 for activation of antiviral innate immunity.NatureImmunology.2016,17(7):806-815.(IF:21.506) [2]Li X, Zhang Q,Shi Q,Liu Y,Zhao K,ShenQ,Shi Y,Liu X,Wang C,Li N,Ma Y,Cao X. Demethylase Kdm6a epigenetically promotes IL-6 and IFN-β production in macrophages.Journal of Autoimmunity. 2017,80:85-94.(IF: 7.76) [3]Li X, Chen G, Li Y, Wang R, Wang L, Lin Z, Gao X, Feng J, Ma Y, Shen B, Li Y, Han G. Involvement of T cell Ig Mucin-3 (Tim-3) in the negative regulation of Inflammatory bowel disease.Clinical Immunology. 2010,134(2):169-177. (IF:4.034) [4]Zhang Q,Zhao K,Shen Q,Han Y,Gu Y,Li X,Zhao D,Liu Y,Wang C,Zhang X,Su X,Liu J,Ge W,Levine RL,Li N,Cao X. Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6.Nature.2015,525(7569):389-393.(the third co-author) (IF:40.137) [5]Ding Y,Guo Z,Liu Y,Li X,Zhang Q,Xu X,Gu Y,Zhang Y,Zhao D,Cao X. The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation.NatureImmunology.2016,17(10):1167-1175.(the second co-author)(IF:21.506) [6]Zhao D, Zhang Q, Liu Y,Li X, Zhao K, Ding Y, Li Z, Shen Q, Wang C, Li N, Cao X. H3K4me3 Demethylase Kdm5a Is Required for NK Cell Activation by Associating with p50 to Suppress SOCS1.Cell Reports.2016,15(2):288-299.(the second co-author) (IF:8.2819) [7]Zhao K,Zhang Q,Li X,Zhao D,Liu Y,Shen Q,Yang M,Wang C,Li N,Cao X. Cytoplasmic STAT4 Promotes Antiviral Type I IFN Production by Blocking CHIP-Mediated Degradation of RIG-I.TheJournalofImmunology.2016,196(3):1209-1217. (the second co-author) (IF:4.8559) [8]Yao Z,Zhang Q,Li X,Zhao D,Liu Y,Zhao K,Liu Y,Wang C,Jiang M,Li N,Cao X. Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcription through histone deacetylase 1 (HDAC1)-mediated histone deacetylation in macrophages.TheJournal of Biological Chemistry.2014,289(13):9372-9379. (the second co-author) (IF:4.125) [9]Liu Y,Zhang Q,Ding Y,Li X,Zhao D,Zhao K,Guo Z,Cao X. Histone lysine methyltransferase Ezh1 promotes TLR-triggered inflammatory cytokine production by suppressing Tollip.TheJournalofImmunology.2015,194(6):2838-2846. (the third co-author) (IF:4.8559)

学术兼职

河南大学抗体药物开发技术国家地方联合工程实验室靶点筛选方向负责人，河南大学转化医学研究所所长，河南大学自然科学学部学术委员会委员，河南大学基础医学院学术委员会委员