当前位置: X-MOL首页全球导师 国内导师 › 张元庆

个人简介

教育经历 2006.09 - 2011.06 中国科学院上海应用物理所 博士 2000.09 - 2004.07 中国科学技术大学 学士 工作经历 2015.10 - 至今 中山大学药学院教授 2011.07 - 2015.10 美国康奈尔大学医学院HMRI博士后

研究领域

高通量微流控芯片用于液体活检和单细胞分析;框架核酸材料在分析方法学中的应用;多功能纳米材料用于癌症的诊断和治疗

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Jie Zhang, Jiacheng Wu, Guanzhao Wang, Luxuan He, Ziwei Zheng, Minhao Wu, Yuanqing Zhang*. Extracellular Vesicles: Techniques and Biomedical Applications Related to Single Vesicle Analysis. ACS Nano. 2023 Sep 26;17(18):17668-17698. Zhengyu Zou, Zhun Lin, Chenglin Wu, Jizhou Tan, Jie Zhang, Yanwen Peng, Kunsong Zhang, Jiaping Li, Minhao Wu*, Yuanqing Zhang*. Micro-Engineered Organoid-on-a-Chip Based on Mesenchymal Stromal Cells to Predict Immunotherapy Responses of HCC Patients. Advanced Science 2023 Sep;10(27):e2302640. doi: 10.1002/advs.202302640. Zhun Lin, Zhengyu Zou, Zhe Pu, Minhao Wu*,Yuanqing Zhang*. Application of Microfluidic Technologies on COVID-19 Diagnosis and Drug Discovery.Acta Pharmaceutica Sinica B. 2023; 13(7):2877-2896. Jizhou Tan, Ting Liu, Wenzhe Fan, Jialiang Wei, Bowen Zhu, Yafang Liu, Lingwei Liu, Xiaokai Zhang, Songling Chen, Haibiao Linc, Yuanqing Zhang*, Jiaping Li*. Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+ cells elimination in hepatocellular carcinoma. Acta Pharmaceutica Sinica B. 2023; 13(2), 632-647 Lingwei Liu, Jialang Zhuang, Jizhou Tan, Ting Liu, Wenzhe Fan, Yuanqing Zhang*, and Jiaping Li*. Doxorubicin-Loaded UiO-66/Bi2S3 Nanocomposite-Enhanced Synergistic Transarterial Chemoembolization and Photothermal Therapy against Hepatocellular Carcinoma. ACS Applied Materials & Interfaces. 2022, 14, 6, 7579–7591. Yan Liu, Zhun Lin, Ziwei Zheng, Yuanqing Zhang*, Lingling Shui*. Accurate Isolation of Circulating Tumor Cells via a Heterovalent DNA Framework Recognition Element Functionalized Microfluidic Chip. ACS Sensors. 2022, 7, 2, 666–673. Siping Liang, Jiaying Li, Zhengyu Zou, Miao Mao, Siqi Ming, Fan Lin, Ziyan Zhang, Can Cao, Jinyu Zhou, Yuanqing Zhang*, Jiaping Li *, Minhao Wu*. Tetrahedral DNA Nanostructures Synergize with MnO2 to Enhance Antitumor Immunity via Promoting STING Activation and M1 Polarization. Acta Pharmaceutica Sinica B. 2022; 12(5), 2494-2505. Liang Chen, Jie Zhang, Zhun Lin, Ziyan Zhang, Miao Mao, Jiacheng Wu, Qian Li, Yuanqing Zhang*, Chunhai Fan*. Pharmaceutical applications of framework nucleic acids. Acta Pharmaceutica Sinica B. 2022; 12(1), 76-91. Invited Review Ziyan Zhang, Qiaojuan Liu, Jizhou Tan, Xiaoxia Zhan, Ting Liu, Yuting Wang, Gen Lu*, Minhao Wu*, Yuanqing Zhang*. Coating with flexible DNA network enhanced T-cell activation and tumor killing for adoptive cell therapy. Acta Pharmaceutica Sinica B. 2021;11, 1965-1977.(Cover story) Fan Lin, Yong Shao, Yingjie Wu, Yuanqing Zhang*. NIR light-Propelled Janus-Based Nanoplatform for Cytosolic-Fueled MicroRNA Imaging. ACS Appl. Mater. Interfaces. 2021; 13(3), 3713-3721. Liang Chen, Siping Liang, Yu Chen, Minhao Wu*, Yuanqing Zhang*. Destructing the Plasma Membrane with Activatable Vesicular DNA Nanopores. ACS Appl. Mater. Interfaces. 2020;12, 1: 96-105. Jialang Zhuang, Jizhou Tan, Chenglin Wu, Jie Zhang, Ting Liu, Chunhai Fan, Jiaping Li*, Yuanqing Zhang*. Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy. Nucleic Acids Research, 2020, 48(16),8870-8882. Yubing Liu, Dabin Chen, Weiqiong Zhang, Yuanqing Zhang*. Mobile DNA tetrahedron on ultra-low adsorption lipid membrane for directional control of cell sensing. Sensors and Actuators B: Chemical. 2020; 307, 127570. Jialang Zhuang, Jie Zhang, Minhao Wu, Yuanqing Zhang* A Dynamic 3D Tumor Spheroid Chip Enables More Accurate Nanomedicine Uptake Evaluation. Advanced Science. 2019; DOI: 10.1002/advs.201901462 Zhiru Wang, Weiwei Qin*, Jialang Zhuang, Minhao Wu, Qian Li, Chunhai Fan*, Yuanqing Zhang*. Virus-Mimicking Cell Capture Using Heterovalency Magnetic DNA Nanoclaws. ACS Appl. Mater. Interfaces. 2019; 11: 12244–12252. Maosheng Xu, Kunsong Zhang, Yubing Liu, Jie Wang, Ke Wang*, Yuanqing Zhang*. Multifunctional MoS2 nanosheets with Au NPs grown in situ for synergistic chemo-photothermal therapy. Colloids and Surfaces B: Biointerfaces 2019; 184, 110510. Ke Wang, Xi Liu, Jialang Zhuang, Yubing Liu, Maosheng Xu, Dong Xie, Junjia Chen*, Xiaoyong Zhang, Yen Wei, Yuanqing Zhang*. Small fluorescent albumin nanoparticles for targeted photothermal therapy via albumin-Binding protein pathways. Colloids and Surfaces B: Biointerfaces 2019; 181,696-704. Jialang Zhuang, Yongjian Wu, Liang Chen, Siping Liang, Minhao Wu, Ledu Zhou, Chunhai Fan, Yuanqing Zhang*. Single‐Cell Mobility Analysis of Metastatic Breast Cancer Cells. Advanced Science. 2018;DOI: 10.1002/advs.201801158. Dabin Chen, Duanping Sun, Zhiru Wang, Weiwei Qin, Liang Chen, Ledu Zhou, Yuanqing Zhang*. A DNA nanostructured aptasensor for the sensitive electrochemical detection of HepG2 cells based on multibranched hybridization chain reaction amplification strategy. Biosensors and Bioelectronics. 2018; 117:416-421. Zijun Zhao, Yu Chen, Ngiambudulu M. Francisco, Yuanqing Zhang*, Minhao Wu*. The application of CAR-T cell therapy in hematological malignancies: Advantages and challenges. Acta Pharmaceutica Sinica B. 2018; 8; 539-551. Duanping Sun, Jing Lu, Dabin Chen, Yunfei Jiang, Zhiru Wang, Weiwei Qin, Yanyan Yu, Zuanguang Chen, Yuanqing Zhang*. Label-free electrochemical detection of HepG2 tumor cells with a self-assembled DNA nanostructure-based aptasensor. Sensors and Actuators B: Chemical. 2018; 268:359-367. Yunfei Jiang, Duanping Sun, Zhixian Liang, Liang Chen, Yuanqing Zhang*, Zuanguang Chen*. Label-free and competitive aptamer cytosensor based on layer-by-layer assembly of DNA-platinum nanoparticles for ultrasensitive determination of tumor cells. Sensors and Actuators B: Chemical. 2018; 262:35-43. Ke Wang, Jialang Zhuang, Yubing Liu, Maosheng Xu, Jingyuan Zhuang, Zuanguang Chen, Yen Wei, Yuanqing Zhang*. PEGylated chitosan nanoparticles with embedded bismuth sulfide for dual-wavelength fluorescent imaging and photothermal therapy. Carbohydrate Polymers. 2018; 184:445-452.

推荐链接
down
wechat
bug