张革 - 中山大学

研究领域

（1）靶向抗肿瘤药物前体的活性及机制研究。（2）肿瘤相关微生物学及疫苗的研究。（3）肿瘤分子标记及早期诊断试剂盒的研究

近期论文

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（1） Wang JY, Zheng YZ, Yang J, Lin YH, Dai SQ, Zhang G* (通讯作者), Liu WL*. Elevated levels of serum amyloid A indicate poor prognosis in patients with esophageal squamous cell carcinoma. BMC Cancer. 2012, 12:365. （2） Wang HS, Chen ZJ, Zhang G, Ou XL, Yang XL, Wong CK, Giesy JP, Du J, Chen SY. A Novel Micro-Linear Vector for In Vitro and In Vivo Gene Delivery and Its Application for EBV Positive Tumors. PLoS One. 2012,7(10):e47159. （3） Zhang G, Liu WL, Zhang L, Wang JY, Kuang MH, Liu P, Lin YH, Dai SQ, Du J. Involvement of Indoleamine 2,3-Dioxygenase in Impairing Tumor-Infiltrating CD8+ T-Cell Functions in Esophageal Squamous Cell Carcinoma. Clin Dev Immunol. 2011, 384726. doi:10.1155/2011/384726. （4） Yi YM, Zhang G, Zeng J, Huang SC, Li LL, Fang R, Jiang GM, Bu XZ, Cai SH, Du J. A new tumor vaccine: FAPτ-MT elicits effective antitumor response by targeting indolamine2,3-dioxygenase in antigen presenting cells. Cancer Biol Ther. 2011, 11(10):866-73. （5） Jiang GM, He YW, Fang R, Zhang G, Zeng J, Yi YM, Zhang S, Bu XZ, Cai SH, Du J. Sodium butyrate down-regulation of indoleamine 2, 3-dioxygenase at the transcriptional and post-transcriptional levels. Int J Biochem Cell Biol. 2010, 42(11):1840-6. （6） Liu WL, Guo XZ, Zhang LJ, Wang JY, Zhang G, Guan S, Chen YM, Kong QL, Xu LH, Li MZ, Song LB, Zeng MS. Prognostic relevance of Bmi-1 expression and autoantibodies in esophageal squamous cell carcinoma. BMC Cancer. 2010, 10:467. （7） Liu P, Xie BL, Cai SH, He YW, Zhang G, Yi YM, Du J. Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes. BMC Cancer. 2009, 9:416. （8） XU BL, Zhang G (共同第一作者), Ye H, Chen G, Zhou J, Pan W et al. The predominance of the Hungarian clone (ST 239-III) amongst hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) isolates recovered throughout mainland China. J Hosp Infect. 2009, 71(3):245-255. （9） Fan J, Shu M, Zhang G, Zhou W, Sharon J, Edward J, et al. Biogeography and Virulence of Staphylococcu saureus. PLOS one. 2009, 4(7)6216 （10） Guo XZ, Zhang G (共同第一作者), Wang JY, Liu WL, Wang F, Dong JQ, Xu LH, Cao JY, Song LB, Zeng MS. Prognostic relevance of Centromere protein H expression in esophageal carcinoma. BMC Cancer. 2008, 8(1):233 （11） Liu WL, Zhang G, Wang JY, Cao JY, Guo XZ, Xu LH, Li MZ, Song LB, Huang WL, Zeng MS. Proteomics-based identification of autoantibody against CDC25B as a novel serum marker in esophageal squamous cell carcinoma. Biochem Biophys Res Commun. 2008, 375(3):440-445 （12） Zou J, Yao Z, Zhang G, Wang H, Xu J, Yew DT, Forster EL. Vaccination of Alzheimer's model mice with adenovirus vector containing quadrivalent foldable Abeta(1-15) reduces Abeta burden and behavioral impairment without Abeta-specific T cell response. J Neurol Sci. 2008, 272(1-2):87-98. （13） He Y, Cai S, Zhang G, Li X, Pan L, Du J. Interfering with cellular signaling pathways enhances sensitization to combined sodium butyrate and GCV treatment in EBV-positive tumor cells。Virus Res. 2008, 135(1):175-180