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研究领域

主要研究领域为药物新型制剂和药物释放系统,特别是药物控释、缓释及靶向药物释放技术。

近期论文

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Y. Tan, Z. Yang, X. Pan, M. Chen , M. Feng, L. Wang, H. Liu, Z. Shan, C. Wu*, Stability and aerosolization of pressurized metered dose inhalers containing thymopentin nanoparticles produced using a bottom-up process. International Journal of Pharmaceutics, 2012, 427(2): 383-390. B. Chen, Z. Wang, G. Quan, X. Peng, X. Pan, R. Wang, Y. Xu, G. Li, C. Wu*. In vitro and in vivo evaluation of ordered mesoporous silica as a novel adsorbent in liquisolid formulation. International Journal of Nanomedicine, 2012, 7: 199-209. Minyan Wei, Yuehong Xu*, Qi Zou, Liuxiao Tu, Chenyi Tang, Ting Xu, Lihe Deng,Chuanbin Wu*. Hepatocellular carcinoma targeting effect of PEGylated liposomes modified with lactoferrin. Eur. J Pharm. Sci.2012,46 (3):131-141. Xu Liu, Ming Lu, Zhefei Guo, Lin Huang, Xin Feng, Chuanbin Wu*, Improving the Chemical Stability of Amorphous Solid Dispersion with Cocrystal Technique by Hot Melt Extrusion. Pharmaceutical Research, 2012, 29( 3): 806-817. Bao Chen, Guilan Quan, Zhouhua Wang, Jianwen Chen, linna Wu, Yuehong Xu, Ge Li,Chuanbin Wu*, Hollow mesoporous silica spheres as a novel drug solution delivery system for poorly water-soluble drugs Powder Technology, In Press, Accepted Manuscript, Available online 5 July 2012. Meimei Zhang, Houli Li, Bo Lang, Kevin O’Donnell, Haohao Zhang, Zhouhua Wang, Yixuan Dong, Chuanbin Wu*, Robert O. Williams III, Formulation and delivery of improved amorphous fenofibrate solid dispersions prepared by thin film freezing, European Journal of Pharmaceutics and Biopharmaceutics,, Available online 4 September 2012 Zhouhua Wang, Bao Chen, Guilan Quan, Feng Li, Qiaoli Wu, Linhui Dian, Yixuan Dong,Chuanbin Wu*, Increasing the Oral Bioavailability of Poorly Water-Soluble Drug Carbamazepine with Immediate-Release Pellets Supported on Mesoporous Silica SBA-15, International Journal of Nanomedicine, Accepted on Oct 16, 2012 Haohao Zhang, Meiwan Chen, Zixin He, Zhouhua Wang, Chuanbin Wu*, Molecular Modeling based Inclusion Mechanism and Stability Studies of Doxycycline and Hydroxypropyl-β-cyclodextrin Complex for Ophthalmic Delivery, AAPS PharmSciTech, Accepted on Oct 12, 2012 Zhiwen Yang, Yinhe Tan, Meiwan Chen, Linghui Dian, Ziyun Shan, Xinsheng Peng,Chuanbin Wu*, Development of Amphotericin B-loaded cubosomes through the SolEmuls technology for enhancing the oral bioavailability, AAPS PharmSciTech, Accepted on Oct 12, 2012 Jianhong Tao, Tiantian Zhang, Jun Xu, Chuanbin Wu*, Analysis of the current situation of antibiotics utilization in China: a hospital-based perspective, Drug Information Journal ,Accepted on Oct 1, 2012 Cuifeng Wang, Xin Luo, Yuefang Zhao, Lina Han, Xin Zeng, Min Feng, Shirong Pan, Hui Peng, Chuanbin Wu, Influence of the polyanion on the physico-chemical properties and biological activities of polyanion/DNA/polycation ternary polyplexes. Acta Biomaterialia, 2012, 8(8): 3014-3026. Xin Luo, Min Feng, Shirong Pan, Yuting Wen, Wei Zhang and Chuanbin Wu, Charge shielding effects on gene delivery of polyethylenimine/DNA complexes: PEGylation and phospholipid coating. Journal of Materials Science: Materials in Medicine , 2012, 23(7): 1685-1695. X. Wen, X. Peng, H. Fu, Y. Dong, K. Han, J. Su, Z. Wang, R. Wang, X. Pan, L. Huang,C. Wu*, Preparation and in Vitro Evaluation of Silk Fibroin Microspheres Produced by a Novel Ultra-fine Particle Processing System, International Journal of Pharmaceutics. Int J Pharm 2011, 416 (1): 195-201. Y. Tan, Z. Yang, X. Peng, F. Xin, Y. Xu, M. Feng, C. Zhao, H. Hu, C. Wu*, A novel bottom-up process to produce nanoparticles containing protein and peptide for suspension in hydrofluoroalkane propellants. International Journal of Pharmaceutics, 2011, 413: 167-173. Z.Yang, X. Peng, Y. T, M. Chen, X. Z, M. Feng, Y. Xu, and C. Wu*, Optimization of the preparation process for an oral phytantriol-based Amphotericin B cubosomes. Journal of Nanomaterials, 2011, doi:10.1155/2011/308016. M. Lu, X. Zhao, L. Chen, X. Xiong, J. Zhang, K. Mai, C. Wu*, Nucleation effect on polymorphism of melt-crystallized syndiotactic polystyrene. Polymer, 2011,52: 1102-1106. K. Han, Z. Wang, X. Peng, B. Chen, X. Wen, Y. Dong, C. Wu*, Transarterial chemoembolization using docetaxel-loaded phytantriol cubic phase precursor for the treatment of hepatocellular carcinoma. J Pharm Sci, 2011, 100: 2240-2247. M. Chen, X. Pan, H. Wu, K. Han, X. Xie, D.E. Wedge, M.A. Repka, C. Wu*, Preparation and anti-bacterial properties of a temperature-sensitive gel containing silver nanoparticles. Pharmazie, 2011, 66 : 272-277. M. Chen, H Wu, Yang Z Yang, X Pan, Y Tan, X Xie, and C. Wu*, Antimicrobial Activity and the Mechanism of Silver Nanoparticles Thermo-sensitive Gel. International Journal of Nanomedicine, 2011,6:2873-2877. Xu Liu, Ming Lu, Zhefei Guo, Lin Huang, Xin Feng, Chuanbin Wu*, Improving the Chemical Stability of Amorphous Solid Dispersion with Cocrystal Technique by Hot Melt Extrusion. Pharmaceutical Research, 2011, 29:806-817.

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