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1．Huang Y, Qin J, Chen M, Chao X, Chen Z, Ramassamy C, Pi R, Jin M. Lithium Prevents Acrolein-Induced Neurotoxicity in HT22 Mouse Hippocampal Cells. Neurochem Res. 2014 Feb 13. [Epub ahead of print] PubMed PMID: 24522749. 2. Chen X, Gao J, Jiang Y, Huang P, Xie Y, Pi R, Zhu S, Yao M. Determination of newly synthesized lipoic acid-niacin dimer in rat plasma by UPLC/electrospray ionization tandem mass spectrometry: assay development, validation and application to a pharmacokinetic study. Biomed Chromatogr. 2014 Feb;28(2):213-7. 3. Ouyang Y, Chen Z, Tan M, Liu A, Chen M, Liu J, Pi R, Fang J. Carvedilol, a third-generation β-blocker prevents oxidative stress-induced neuronal death and activates Nrf2/ARE pathway in HT22 cells. Biochem Biophys Res Commun. 2013 Nov 29;441(4):917-22. 4. Daqian Zhu, Qi Liu, Bingling Luo, Meihui Chen, Rongbiao Pi, Peng Huang, Shijun Wen. Synthesis of Carbazoles via One-Pot Copper-Catalyzed Amine Insertion into Cyclic Diphenyleneiodoniums as a Strategy to Generate a Drug-Like Chemical Library. Advanced Synthesis & Catalysis. 2013，355（11-12）2172–2178. 5. Tan M, Ouyang Y, Jin M, Chen M, Liu P, Chao X, Chen Z, Chen X, Ramassamy C, Gao Y*, Pi R*. Downregulation of Nrf2/HO-1 pathway and activation of JNK/c-Jun pathway are involved in homocysteic acid-induced cytotoxicity in HT-22 cells. Toxicol Lett. 2013 Aug 27;223(1):1-8. 6. Zhu D, Chen M, Li M, Luo B, Zhao Y, Huang P, Xue F, Rapposelli S, Pi R*, Wen S*. Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity. Eur J Med Chem. 2013 Aug 9;68C:81-88. 7. Zhao ZM, Sun ZH, Chen MH, Liao Q, Tan M, Zhang XW, Zhu HD, Pi RB, Yin S. Neuroprotective polyhydroxypregnane glycosides from Cynanchum otophyllum. Steroids.2013 Oct;78(10):1015-20. 8. Jiang Y, Zou Y, Chen S, Zhu C, Wu A, Liu Y, Ma L, Zhu D, Ma X, Liu M, Kang Z, Pi R, Peng F, Wang Q, Chen X. The anti-inflammatory effect of donepezil on experimental autoimmune encephalomyelitis in C57 BL/6 mice. Neuropharmacology. 2013 Oct;73:415-24. 9. Jiang Y, Wu A, Zhu C, Pi R, Chen S, Liu Y, Ma L, Zhu D, Chen X. The protective effect of berberine against neuronal damage by inhibiting matrix metalloproteinase-9 and laminin degradation in experimental autoimmune encephalomyelitis. Neurol Res. 2013 May;35(4):360-8. 10. Huang Y, Jin M, Pi R*, Zhang J, Chen M, Ouyang Y, Liu A, Chao X, Liu P, Liu J,Ramassamy C, Qin J*. Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells. Neurosci Lett.2013 Feb 22;535:146-51. 11. Huang YJ, Jin MH, Pi RB*, Zhang JJ, Ouyang Y, Chao XJ, Chen MH, Liu PQ, Yu JC, Ramassamy C, Dou J, Chen XH, Jiang YM, Qin J*. Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo. Toxicol Lett. 2013 Mar 13;217(3):184-91. 12. Zhao ZY, Luan P, Huang SX, Xiao SH, Zhao J, Zhang B, Gu BB, Pi RB, Liu J. Edaravone protects HT22 neurons from H2O2-induced apoptosis by inhibiting the MAPK signaling pathway. CNS Neurosci Ther. 2013 Mar;19(3):163-9. 13. Chen X, Chen S, Jiang Y, Zhu C, Wu A, Ma X, Peng F, Ma L, Zhu D, Wang Q, Pi R. Minocycline reduces oxygen-glucose deprivation-induced PC12 cell cytotoxicity via matrix metalloproteinase-9, integrin β1 and phosphorylated Akt modulation. Neurol Sci. 2013 Aug;34(8):1391-6. 14. Yu SS, Cai Y, Ye JT, Pi RB, Chen SR, Liu PQ, Shen XY, Ji Y. Sirtuin 6 protects cardiomyocytes from hypertrophy in vitro via inhibition of NF-κB-dependent transcriptional activity. Br J Pharmacol. 2013 Jan;168(1):117-28. 15. Doggui S, Belkacemi A, Paka GD, Perrotte M, Pi R, Ramassamy C. Curcumin protects neuronal-like cells against acrolein by restoring Akt and redox signaling pathways. Mol Nutr Food Res. 2013 Sep;57(9):1660-70. 16.王观峰，姚敏，李文立，邹秀兰，邹玉平，皮荣标. 硫辛酸烟酸二联体对丙烯醛损伤ARPE-19细胞的保护作用[J]. 眼科新进展,2013,02:106-109. 17. Huang WY, Chao XJ, Ouyang Y, Liu AM, He XX, Chen MH, Wang LH, Liu J, Yu SW, Rapposelli S, RB Pi*. Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer Against Alzheimer's Disease, Prevents Oxidative Stress-Induced Neuronal Death Through Activating Nrf2/ARE/HO-1 Pathway in HT22 Cells. CNS Neurosci Ther. 2012 Nov;18(11):950-1. 18. Chao X, He X, Yang Y, Zhou X, Jin M, Liu S, Cheng Z, Liu P, Wang Y, Yu J, Tan Y, Huang Y, Qin J, Rapposelli S, RB Pi*. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease. Bioorg Med Chem Lett. 2012 Oct 15;22(20):6498-502. 19. Xiao O, Xie ZL, Lin BW, Yin XF, RB Pi*, Zhou SY*. Minocycline inhibits alkali burn-induced corneal neovascularization in mice. PLoS One. 2012;7(7):e41858. 20. Chen X, Ma L, Jiang Y, Chen S, Zhu C, Liu M, Ma X, Zhu D, Liu Y, Peng F, Wang Q, Pi R. Minocycline up-regulates the expression of brain-derived neurotrophic factor and nerve growth factor in experimental autoimmune encephalomyelitis. Eur J Pharmacol. 2012 Jul 5;686(1-3):124-9.