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目前主要开展新药筛选及靶标构建、细胞自噬发生机制及相关调节剂研究。

近期论文

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1、Si Gao; Hong Li; Yi Cai, Jian-tao Ye; Jing Lu; Xiao-yang Huang; Xiao-jun Feng; Zhi-ping Liu; Shao-rui Chen, Min Li*, and Peiqing Liu*, Mitochondrial binding of α-enolase stabilizes mitochondrial membrane: its role in doxorubicin-induced cardiomyocyte apoptosis, Arch. Biochem. Biophys., 2014, 542, 46-55 (IF: 3.37) 2、Min Li, Bilon Khambu, Hao Zhang, Jeong-Han Kang, Xiaoyun Chen, Daohong Chen, Laura Vollmer, Pei-Qing Liu, Andreas Vogt and Xiao-Ming Yin*, Suppression of lysosome function induces autophagy via a feedback downregulation of MTORC1 activity, J. Biol. Chem., 2013, 288, 35769-35780 (IF: 4.65) 3、Chih-Wen Lin, Hao Zhang, Min Li, Xiwen Xiong, Xi Chen, Xiaoyun Chen, X. Charlie Dong and Xiao-Ming Yin*, Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice, J. Hepatology, 2013, 58, 993-999 (IF: 9.85) 4、Daohong Chen, Xi Chen, Min Li, Hao Zhang, Wen-Xing Ding, Xiao-Ming Yin*. CCCP-Induced LC3 lipidation depends on Atg9 whereas FIP200/Atg13 and Beclin 1/Atg14 are dispensable, Biochem. Biophys. Res. Commun.,2013, 432, 226-230 (IF: 2.40) 5、Xi Chen, Min Li, Daohong Chen, Wentao Gao, Jun-Lin Guan, Massaki Komatsu and Xiao-Ming Yin*. Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis, PLOS One, 2012, 7(12): e52347. doi:10.1371/journal.pone.0052347 (IF: 3.73) 6、Wen-Xing Ding, Min Li, Joanna M. Biazik, David G. Morgan, Fengli Guo, Hong-Min Ni, Michael Goheen, Eeva-Liisa Eskelinen, and Xiao-Ming Yin*. Electron Microscopic Analysis of a Spherical Mitochondrial Structure, J. Biol. Chem., 2012, 287, 42373-42378 (IF: 4.65) 7、Min Li, Xi Chen, Qi-Zhuang Ye, Andreas Vogt and Xiao-Ming Yin*. A High-throughput FRET-based Assay for Determination of Atg4 Activity, Autophagy, 2012, 8,401-412 (IF:12.04) 8、Jeong-han Kang, Min Li, Xi Chen and Xiao-Ming Yin*, Proteomics analysis of starved cells revealed Annexin A1 as an important regulator of autophagic degradation, Biochem. Biophys. Res. Commun., 2011, 407, 581-586 (IF: 2.48) 9、Min Li, Yifeng Hou, Wang Jinsong, Xiaoyun Chen, Zhi-Ming Shao and Xiao-Ming Yin*, Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates, J. Biol. Chem., 2011, 286, 7327–7338 (IF: 4.77) 10、Wen-Xing Ding, Min Li, and Xiao-Ming Yin*, Selective taste of ethanol-induced autophagy for mitochondria and lipid droplets, Autophagy, 2011, 7, 248-249 (IF: 7.45) 11、Wen-Xing Ding, Min Li, Xiaoyun Chen, Hong-Min Ni, Chie-Wen Lin, Wentao Gao, Binfeng Lu, Donna B. Stolz, Dahn L. Clemens and Xiao-Ming Yin*, Autophagy reduces acute ethanol induced hepatotoxicity and steatosis in mice, Gastroenterology, 2010, 139, 1740-1752 (IF: 12.0) 12、Wen-Xing Ding, Hong-Min Ni, Min Li, Yong Liao, Xi Chen, Donna B. Stolz, Gerald W. Dorn II and Xiao-Ming Yin*, Nix is critical to two distinct phases of mitophagy: reactive oxygen species-mediated autophagy induction and parkin-ubiqutin-p62-mediated mitochondria priming, J. Biol. Chem. 2010, 285, 27879-27890 (IF: 5.31) 13、Min Li, Qing Yang, Lianwen Zhang, Han Li, Yunluan Cui and Qingyu Wn*, Identification of novel targets of cyanobacterial glutaredoxins, Arch. Biochem. Biophys., 2007, 458, 220-228 (IF: 2.57) 14、Min Li, Qing Yang, Yang Gao and Qingyu Wu*. N-terminus deletion affecting the praperation of soluble cyanobacterial glutaredoxin in Escherichia coli, Biochemisty (Moscow), 2007, 72, 383-391 (IF: 1.47) 15、Lianwen Zhang, Min Li and Qingyu Wu*. Influence of ultraviolet-C on structure and function of Synechococcus sp. PCC 7942 photolyase, Biochemistry(Moscow), 2007, 72, 668-673 (IF: 1.47) 16、李民*,冯银刚,高扬,吴庆余,谷氧还蛋白系统及其对细胞氧化还原态势的调控,生物物理学报, 2007, 23, 343-350 17、Min Li, Wei Huang, Qing Yang, Xingguo Liu and Qingyu Wu*. Expression and oxidative stress tolerance studies of glutaredoxin from cyanobacterium Synechocystis sp. PCC 6803 in Escherichia coli, Protein Expr. Purif., 2005, 42, 85-91 (IF: 1.55) 18、Xingguo Liu, Wei Huang, Min Li and Qingyu Wu*, Purification and characterization of two small heat shock proteins from Anabaena sp. PCC 7120, IUBMB Life, 2005,57,449-54(IF: 1.77) 19、Qing Yang*, Min Li, Jianqiang Xu, Yongming Bao and Lijia An*. Expression of gloshedobin, a thrombin-like enzyme from the venom of Gloydius shedaoensis, in Escherichia coli, Biotechnol. Lett., 2003, 25, 101-105 (IF: 0.8) 20、李民,杨青,雷旭宇,安利佳*,蛇毒类凝血酶基因在大肠杆菌中的融合表达及纯化,无锡轻工大学学报, 2003, 2, 22-25

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