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1. Chen, S.-B.; Wu, W.-B.; Hu, M.-H.; Ou, T.-M.; Gu, L.-Q.; Tan, J.-H.*; Huang, Z.-S*. Discovery of a new fluorescent light-up probe specific to parallel G-quadruplexes. Chemical Communications 2014, 50, 12173-12176. 2. Yan, J.-W.; Chen, S.-B.; Liu, H.-Y.; Ye, W.-J.; Ou, T.-M.; Tan, J.-H.*; Li, D.; Gu, L.-Q.; Huang, Z.-S*. Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids. Chemical Communications 2014, 50, 6927-6930. 3. Wang, X.; Zhou, C.-X.; Yan, J.-W.; Hou, J.-Q.; Chen, S.-B.; Ou, T.-M.; Gu, L.-Q.; Huang, Z.-S.; Tan, J.-H*. Synthesis and evaluation of quinazolone derivatives as a new class of c-KIT G-quadruplex binding ligands. ACS Medicinal Chemistry Letters 2013, 4, 909-914. 4. Chen, S.-B.; Shi, Q.-X.; Peng, D.; Huang, S.-Y.; Ou, T.-M.; Li, D.; Tan, J.-H.*; Gu, L.-Q.; Huang, Z.-S. The role of positive charges on G-quadruplex binding small molecules: Learning from bisaryldiketene derivatives. Biochimica et Biophysica Acta, General Subjects 2013, 1830, 5006-5013. 5. Yan, J.-W.; Ye, W.-J.; Chen, S.-B.; Wu, W.-B.; Hou, J.-Q.; Ou, T.-M.; Tan, J.-H.*; Li, D.; Gu, L.-Q.; Huang, Z.-S*. Development of a universal colorimetric indicator for G-quadruplex structures by the fusion of thiazole orange and isaindigotone skeleton. Analytical Chemistry 2012, 84, 6288-6292. 6. Yan, J.-W.; Li, Y.-P.; Ye, W.-J.; Chen, S.-B.; Hou, J.-Q.; Tan, J.-H.*; Ou, T.-M.; Li, D.; Gu, L.-Q.; Huang, Z.-S*. Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation. Bioorganic & Medicinal Chemistry 2012, 20, 2527-2534. 7. Chen, S.-Y.; Chen, Y.; Li, Y.-P.; Chen, S.-H.; Tan, J.-H.*; Ou, T.-M.; Gu, L.-Q.; Huang, Z.-S*. Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer's disease. Bioorganic & Medicinal Chemistry 2011, 19, 5596-5604. 8. Chen, S.-B.; Tan, J.-H.*; Ou, T.-M.; Huang, S.-L.; An, L.-K.; Luo, H.-B.; Li, D.; Gu, L.-Q.; Huang, Z.-S*. Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand. Bioorganic & Medicinal Chemistry Letters 2011, 21, 1004-1009. 9. An, Z.-Y.; Yan, Y.-Y.; Peng, D.; Ou, T.-M.; Tan, J.-H.*; Huang, S.-L.; An, L.-K.; Gu, L.-Q.; Huang, Z.-S*. Synthesis and evaluation of graveoline and graveolinine derivatives with potent anti-angiogenesis activities. European Journal of Medicinal Chemistry 2010, 45, 3895-3903. 10. Tan, J.-H.; Ou, T.-M.; Hou, J.-Q.; Lu, Y.-J.; Huang, S.-L.; Luo, H.-B.; Wu, J.-Y.; Huang, Z.-S.; Wong, K.-Y.; Gu, L.-Q. Isaindigotone Derivatives: A New Class of Highly Selective Ligands for Telomeric G-Quadruplex DNA. Journal of Medicinal Chemistry 2009, 52, 2825-2835. 11. Tan, J.-H.; Gu, L.-Q.; Wu, J.-Y. Design of selective G-quadruplex ligands as potential anticancer agents. Mini-Reviews in Medicinal Chemistry 2008, 8, 1163-1178. 12. Tan, J.-H.; Lu, Y.-j.; Huang, Z.-S.; Gu, L.-Q.; Wu, J.-Y. Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin. European Journal of Medicinal Chemistry 2007, 42, 1169-1175. 13. Tan, J. H.; Zhang, Q. X.; Huang, Z. S.; Chen, Y.; Wang, X. D.; Gu, L. Q.; Wu, J. Y. Synthesis, DNA binding and cytotoxicity of new pyrazole emodin derivatives. European Journal of Medicinal Chemistry 2006, 41, 1041-1047.