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1.Ou, T.M., et al., Inhibition of cell proliferation by quindoline derivative (SYUIQ-05) through its preferential interaction with c-myc promoter G-quadruplex. J Med Chem, 2011. 54(16): p. 5671-9. 2. Ou, T.M., et al., G-quadruplexes: targets in anticancer drug design. ChemMedChem, 2008. 3(5): p. 690-713. 3. Ou, T.M., et al., Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives. J Med Chem, 2007. 50(7): p. 1465-74. 4. Wang, X.D., et al., Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives. J Med Chem, 2010. 53(11): p. 4390-8. 5. Tan, J.H., et al., Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA. J Med Chem, 2009. 52(9): p. 2825-35. 6. Lu, Y.J., et al., 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation. J Med Chem, 2008. 51(20): p. 6381-92. 7. Zhou, J.L., et al., Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase. J Med Chem, 2005. 48(23): p. 7315-21. 8. Lin, J., et al., Effective detection and separation method for G-quadruplex DNA based on its specific precipitation with Mg(2+). Biomacromolecules, 2010. 11(12): p. 3384-9. 9. Liao, S.R., et al., 12-N-Methylated 5,6-dihydrobenzo[c]acridine derivatives: A new class of highly selective ligands for c-myc G-quadruplex DNA. Eur J Med Chem, 2012. 53C: p. 52-63. 10. Chen, W.J., et al., Disubstituted 1,8-dipyrazolcarbazole derivatives as a new type of c-myc G-quadruplex binding ligands. Bioorg Med Chem, 2012. 20(9): p. 2829-36. 11. Yan, J.W., et al., Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation. Bioorg Med Chem, 2012. 20(8): p. 2527-34. 12. Li, Z., et al., 2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling. J Enzyme Inhib Med Chem, 2012. 13. Xiao, N., et al., Interaction of Berberine derivative with protein POT1 affect telomere function in cancer cells. Biochem Biophys Res Commun, 2012. 419(3): p. 567-72. 14. Li, Z., et al., Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA. Eur J Med Chem, 2012. 47(1): p. 299-311. 15. Chen, S.Y., et al., Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer's disease. Bioorg Med Chem, 2011. 19(18): p. 5596-604. 16. Hou, J.Q., et al., Impact of planarity of unfused aromatic molecules on G-quadruplex binding: learning from isaindigotone derivatives. Org Biomol Chem, 2011. 9(18): p. 6422-36. 17. Wu, W.B., et al., Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors. Eur J Med Chem, 2011. 46(8): p. 3339-47. 18. Ma, Y., et al., Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: a new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene. Eur J Med Chem, 2011. 46(5): p. 1906-13. 19. Wu, W.B., et al., Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA. Org Biomol Chem, 2011. 9(8): p. 2975-86. 20. Li, Y.P., et al., Syntheses and characterization of novel oxoisoaporphine derivatives as dual inhibitors for cholinesterases and amyloid beta aggregation. Eur J Med Chem, 2011. 46(5): p. 1572-81.