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1. “Mechanistic studies on the anticancer activity of 2,4-disubstituted quinazoline derivative” Su, L.; Zheng, H.; Li, Z.; Qiu, J.; Chen, S.; Liu, J.; Ou, T.-M.; Tan, J.-H.; Gu, L.-Q.; Huang, Z.-S.; Li, D.* Biochim. Biophys. Acta - General Subjects 2014, 1840, 3123-3130. 2. “Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols” Ge, H.a; Liu, J.a; Zhao, W.; Wang, Y.; He, Q.; Wu, R.; Li, D.*; Xu, J.* Org. Biomol. Chem. 2014, 12, 4941-4951. (Highlighted by Chemistry World; a. The first two authors contributed equally to this work) 3. “Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids” Yan, J.; Chen, S.; Liu, H.; Ye, W.; Ou, T.-M.; Tan, J.-H.*; Li, D.; Gu, L.-Q.; Huang, Z.-S.* Chem. Comm. 2014, 50, 6927-6930. 4. “Cellular nucleic acid binding protein suppresses tumor cell metastasis and induces tumor cell death by downregulating heterogeneous ribonucleoprotein K in fibrosarcoma cells” Qiu, J.; Chen, S.; Su, L.; Liu, J.; Xiao, N.; Ou, T.-M.; Tan, J.-H.; Gu, L.-Q.*; Huang, Z.-S.*; Li, D.* Biochim. Biophys. Acta - General Subjects 2014, 1840, 2244-2252. 5. “G-quadruplex-mediated regulation of telomere binding protein POT1 gene expression” He, Q.; Zeng, P.; Tan, J.-H.; Ou, T.-M.; Gu, L.-Q.; Huang, Z.-S.; Li, D.* Biochim. Biophys. Acta - General Subjects 2014, 1840, 2222-2233. 6. “Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease” Liu, J.; Qiu, J.; Wang, M.; Wang, L.; Su, L.; Gao, J. Gu, Q.; Xu, J.; Huang, S.-L.; Gu, L.-Q.; Huang, Z.-S.*; Li, D.* Biochim. Biophys. Acta - General Subjects 2014, 1840, 2886-2903. 7. “Syntheses and characterization of non-bisphosphonate quinoline derivatives as new FPPS inhibitors” Liu, J.; Liu, W.; Ge, H.; Gao, J.; He, Q.; Su, L.; Xu, J.; Gu, L.-Q.; Huang, Z.-S.; Li, D.* Biochim. Biophys. Acta - General Subjects 2014, 1840, 1051-1062. 8. “Mechanistic studies for the role of cellular nucleic-acid-binding protein (CNBP) in regulation of c-myc transcription” Chen, S.; Su, L.; Qiu, J.; Xiao, N.; Lin, J.; Tan, J.-H.; Ou, T.-M.; Gu, L.-Q.*; Huang, Z.-S.*; Li, D.* Biochim. Biophys. Acta - General Subjects 2013, 1830, 4769-4777. 9. “Multi-target-directed design, syntheses, and characterization of fluorescent bisphosphonate derivatives as multifunctional enzyme inhibitors in mevalonate pathway” Gao, J.; Liu, J.; Qiu, Y.; Chu, X.; Qiao, Y; Li, D.* Biochim. Biophys. Acta - General Subjects 2013, 1830, 3635-3642. featured online on Global Medical Discovery [ISSN 1929-8536] (http://globalmedicaldiscovery.com) 10. “Interaction of berberine derivative with protein POT1 affect telomere function in cancer cells” Xiao, N.; Chen, S.; Ma, Y.; Qiu, J.; Tan, J.-H.; Ou, T.-M.; Gu, L.-Q.; Huang, Z.-S.; Li, D.* Biochem. Biophys. Res. Comm. 2012, 419 (3), 567-572. （featured online on Global Medical Discovery [ISSN 1929-8536] (http://globalmedicaldiscovery.com) 11. “Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA” Li, Z.; Tan, J.-H.; He, J.-H.; Long, Y.; Ou, T.-M.; Li, D.*; Gu, L.-Q.; Huang, Z.-S.* Euro. J. Med. Chem. 2012, 47, 299-311. 12. “Design, synthesis, and characterization of piperazinedione-based dual protein inhibitors for both farnesyltransferase and geranylgeranyltransferase-I” Qiao, Y.; Gao, J.; Qiu, Y.; Wu, L.; Guo, F.; Lo, K.-W.; Li, D.* Euro. J. Med. Chem. 2011, 46, 2264-2273. 13. “Discovery of potent inhibitor for farnesyl pyrophosphate synthase in mevalonate pathway” Gao, J.; Chu, X.; Qiu, Y.; Wu, L.; Qiao, Y.; Wu, J.; Li, D.* Chem. Comm. 2010, 46, 5340-5342. 14. “Oct-2-en-4-ynoyl-CoA as a specific inhibitor of acyl-CoA oxidase” Zeng, J.; Wu, L.; Zhang, X.; Liu, Y.; Deng, G.; Li, D.* Org. Lett. 2008, 10 (19), 4287-4290. 15. “Comparative inhibition studies of enoyl-CoA hydratase 1 and enoyl-CoA hydratase 2 in long-chain fatty acid oxidation” Wu, L.; Lin, S.; Li, D.* Org. Lett. 2008, 10 (15), 3355-3358. 16. “Oct-2-yn-4-enoyl-CoA as a multifunctional enzyme inhibitor in fatty acid oxidation” Wu, L.; Liu, X.; Li, D.* Org. Lett. 2008, 10 (11), 2235-2238. 17. “Inactivation of thiolase by 2-alkynoyl-CoA via its intrinsic isomerase activity” Wu, L.; Zeng, J.; Deng, G.; Guo, F.; Li, N.; Liu, X.; Chu, X.; Li, D.* Org. Lett. 2007, 9 (20), 3877-3880. 18. “Bifunctional inhibitors of mevalonate kinase and mevalonate 5-diphosphate decarboxylase” Qiu, Y.; Li, D.* Org. Lett. 2006, 8 (6), 1013-1016. 19. “Intrinsic isomerase activity of medium-chain acyl-CoA dehydrogenase” Zeng, J.; Li, D.* Biochemistry 2005, 44 (17), 6715-6722. 20. “Crystal structure of precorrin-8x methyl mutase” Shipman, L.a,*; Li, D.a; Roessner, C.; Scott, A.; Sacchettini, J.* Structure 2001, 9 (7), 587-596. (a. The first two authors contributed equally to this work)