个人简介
教育经历
2005/09─2009/07，吉林大学，公共卫生学院放射医学专业，研究生/博士
2003/09─2005/07，吉林大学，公共卫生学院放射医学专业，研究生/硕士
1996/09─2001/07，吉林大学（原白求恩医科大学），预防医学系，本科/学士
工作经历
2022/03─至今，吉林大学，公共卫生学院卫生部放射生物学重点实验室，教授。
2015/02─2016/02，Rutgers, The State University of New Jersey，访问学者。
2014/10─2022/03，吉林大学，公共卫生学院卫生部放射生物学重点实验室，副教授。
2006/09─2014/09，吉林大学，公共卫生学院卫生部放射生物学重点实验室，讲师。
2001/07─2006/08，吉林大学，公共卫生学院卫生部放射生物学重点实验室，助教。
社会兼职
中国毒理学会特种医学毒理专业委员会第一届委员会委员, 2022/01-2026/01
吉林省核学会第八届常务理事, 聘期四年, 2022-2026
中国环境诱变剂学会辐射与健康专业委员会第一届委员会委员， 2021/09-2025/09
第十一届中国生物物理学会辐射与环境生物物理学分会理事, 2021/05-2025/05
中国核学会核应急医学分会第一届理事会理事, 2020/09-2024/09
中华医学会放射医学与防护分会青年委员会副主任委员, , 2019/11˗2023/11
中华预防医学会放射卫生专业委员会第五届委员会青年委员,2019/09-2024/09
医学参考报放射医学与防护频道第二届编辑委员会编委, 聘期四年, 2016-2019
吉林省核学会第六届常务理事, 聘期四年, 2014-2018
近期论文
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Yuexuan Wang; Yu Han; Yuzhen Jin; Qiang He; Zhicheng Wang. The Advances in Epigenetics for Cancer Radiotherapy. International Journal of Molecular Sciences.2022, 23(10):5654. (通讯作者)
Weiqiang Xu; Fang Fang; Yuexuan Wang; Lijing Qin; Yu Han; Yuwei Huang; Bin Li; Yang Liu; Zhicheng Wang. Co-overexpression of TRAIL and Smac sensitizes MDA-MB-231 cells to radiation through apoptosis depending on mitochondrial pathway. Radiation and Environmental Biophysics.2022, 61(1):37-48. (通讯作者)
Yitong Li, Ruihang Zhang, Zhen Xu, Zhicheng Wang. Advances in Nanoliposomes for the Diagnosis and Treatment of Liver Cancer. Int J Nanomedicine. 2022,17:909-925. (通讯作者)
Lei Yu, Xiangshan Yang, Xin Li, Lijing Qin, Weiqiang Xu, Hongli Cui, Zhen Jia, Qiang He, Zhicheng Wang. Pink1/PARK2/mROS-Dependent Mitophagy Initiates the Sensitization of Cancer Cells to Radiation. Oxid Med Cell Longev. 2021,2021:5595652. (通讯作者)
Hou Jiguang, Fang Fang, Kang Shuna, Wang Zhicheng,Yang Yanming. Curcumin from Jianghuang （Rhizoma Curcumae Longae） protects against exposure to ultraviolet B by antioxidation and attenuating mitochondrion-dependent apoptosis. J Tradit Chin Med. 2020, 40(5):782-791. (通讯作者)
Yana Li, Zhicheng Wang, Jingji Jin, Shuang-Xi Zhu, Gan-Qing He, Sui-Hui Li, Jianfeng Wang, Yong Cai. Quercetin pretreatment enhances the radiosensitivity of colon cancer cells by targeting Notch-1 pathway. Biochem Biophys Res Commun. 2020, 523(4):947-953.
Xin Li, Fang Fang, Ying Gao, Geng Tang, Weiqiang Xu, Yihan Wang, Ruoxian Kong, Ayixianguli Tuyihong, Zhicheng Wang. ROS Induced by KillerRed Targeting Mitochondria (mtKR) Enhances Apoptosis Caused by Radiation via Cyt c/Caspase-3 Pathway. Oxid Med Cell Longev. 2019, 2019:4528616. (通讯作者)
Yanming Yang, Fang Fang, Xin Li, Lei Yu, Zhicheng Wang. TRAIL overexpression co-regulated by Egr1 and HRE enhances radiosensitivity of hypoxic A549 cells depending on its apoptosis inducing role. Oncol Rep. 2017, 37(1):533-539. (通讯作者)
Xiangfu Song, Ting Ren, Zhou Zheng, Tiancheng Lu, Zhicheng Wang, Fengguo Du, Haibin Tong. Anti-tumor and immunomodulatory activities induced by an alkali-extracted polysaccharide BCAP-1 from Bupleurum chinense via NF-κB signaling pathway. Int J Biol Macromol, 2017, 95:357-362. (通讯作者)
Xiaojing Jia, Zhicheng Wang, Ling Qiu, Yanming Yang, Yunlong Wang, Zhishen Chen, Zhongshan Liu, Lei Yu. Upregulation of LncRNA-HIT promotes migration and invasion of non-small cell lung cancer cells by association with ZEB1. Cancer Med, 2016, 5(12):3555-3563.
Zhicheng Wang, Jianfeng Wang, Yanbo Li, Caixia Guo, Yang Liu, Fang Fang, Shouliang Gong, Involvement of endoplasmic reticulum stress in apoptotic death of testicular cells induced by low-dose radiation, J Huazhong Univ Sci Technolog Med Sci, 2013, 33(4):551-558.
Jianfeng Wang, Yana Li, Yang Liu, Yanbo Li, Shouliang Gong, Fang Fang, Zhicheng Wang, Overexpression of truncated AIF regulated by Egr1 promoter radiation-induced apoptosis on MCF-7 cells, Radiat Environ Biophys, 2015, 54(4):413-421. (通讯作者)
Weiwu Liu, Yang Liu, Shuo Liang, Jiahui Wu, Zhicheng Wang, Shouliang Gong, Hypoxia- and radiation-induced overexpression of Smac by an adenoviral vector and its effects on cell cycle and apoptosis in MDA-MB-231 human breast cancer cells, Exp Ther Med, 2013, 6(6):1560-1564. (通讯作者)
Fang Fang, Pingsheng Gong, Hongguang Zhao, Yujing Bi, Gang Zhao, Shouliang Gong, Zhicheng Wang, Mitochondrial modulation of apoptosis induced by low-dose radiation in mouse testicular cells, Biomed Environ Sci, 2013, 26(10):820-830. (通讯作者)
Zhenlan Li, Shuo Liang, Zhicheng Wang, Yanbo Li, Caixia Guo, Fang Fang, Shouliang Gong, Chenghe Lin, Expression of Smac induced by the Egr1 promoter enhances the radiosensitivity of breast cancer cells, Cancer Gene Ther, 2014, 21(4):142-149.
Jiahui Wu, Hongfang Wang, Zhicheng Wang, Kai Xu, Yali Qi,Jinhua Li,Shouliang Gong, Ya Liu, Yang Liu, Conditionally replicating adenovirus combined with gene-targeted radiotherapy induces apoptosis via TRAIL death receptors in MDA-MB-231 cells, Mol Med Rep, 2013, 8(1): 299-305.
Yanbo Li, Caixia Guo, Zhicheng Wang, Lihua Dong, Feng Guan, Yang Liu, Hongfang Wang, Zhiwei Sun, Shouliang Gong. Radiosensitization of breast cancer cells by TRAIL-endostatin-targeting gene therapy. Neoplasma, 2013, 60(6):613-619.
Yanbo Li, Caixia Guo, Zhicheng Wang, Pingsheng Gong, Zhiwei Sun, Shouliang Gong. Enhanced effected of TRAIL-endostatin-based double-gene-radiotherapy on suppressing growth, promoting apoptosis and inducing cell cycle arrest in vascular endothelial cells. Journal of Huazhong University of Science and Technology (Medical Sciences), 2012, 32(2):153-157.
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