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个人简介

讲授课程: 卫生毒理学、分子毒理学、靶器官毒理学、毒理学实验技术、毒理学研究进展、毒理学安全性评价 教育经历: 2003/09–2008/06,吉林大学公共卫生学院,本科生(预防医学) 2008/09–2010/06,吉林大学公共卫生学院,硕士(环境卫生与劳动卫生) 2012/05–2017/06,加拿大阿尔伯塔大学,博士(分析与环境毒理) 工作经历: 2017/07–至今,吉林大学,公共卫生学院,副教授

研究领域

环境毒理学新药的毒理学安全性评价

科研项目: 1.Identificationofnewwaterdisinfectionbyproductsofhealthimportance,加拿大NSERCStrategic项目,2015-2018,45万加元,参与。 2.ResearchinAnalytical/EnvironmentalChemistryandToxicology,加拿大NSERCCreate项目,2014-2019,15万加元,参与。 3.Noveltoolsforcharacterizationofnewdrinkingwaterdisinfectionbyproductsandhealtheffects,加拿大NSERCStrategic项目,2011-2015,54万加元,参与。 4.新型稀土杂多化合物抗乙型肝炎病毒的候选药物研究,国家十一五重大项,2009-2010,241万元,参与。 5.新型铌取代的杂多化合物抗乙肝病毒活性研究,吉林大学研究生创新研究课题,2010-2011,1.2万元,主持。 6.国家自然科学基金面上项目,乳腺癌干细胞辐射抗性的功能蛋白组学研究,2010-2012,28万元,参与。 7.国家自然科学基金面上项目,磁性纳米粒子偶联的携带TRAIL和Smac双基因的条件复制型腺病毒联合放疗、热疗治疗肝癌的实验研究,2009-2011,35万元,参与。

近期论文

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学术论文: 1.JinhuaLi,MadlenBauer,BirgetMoe,ElaineM.Leslie,Xing-FangLi,Multidrugresistanceprotein4(MRP4/ABCC4)protectscellsfromthetoxiceffectsofhalobenzoquinones.Chem.Res.Toxicol.,2017,30(10):1815-1822. 2.HanyongPeng,BinHu,QingqingLiu,JinhuaLi,Xing-FangLi,HongquanZhang,andX.ChrisLe.Methylatedphenylarsenicalmetabolitesdiscoveredinchickenliver.Angew.Chem.Int.Ed.,2017,56,6773. 3.KatherineZ.Fu,JinhuaLi,SaiVemula,BirgetMoe,andXing-FangLi.Effectsofhalobenzoquinoneandhaloaceticacidwaterdisinfectionbyproductsonhumanneuralstemcells.J.Environ.Sci.,2017,58,239-249.(co-firstauthor) 4.JinhuaLi,BirgetMoe,SaiVemula,WeiWang,andXing-FangLi.Emergingdisinfectionby-products,halobenzoquinones:effectsofisomericstructureandhalogensubstitutiononcytotoxicity,formationofreactiveoxygenspecies,andgenotoxicity.Environ.Sci.Technol.,2016,50(13),6744–6752. 5.XiaowenYan,JinhuaLi,QingqingLiu,HanyongPeng,AleksandraPopowich,ZhixinWang,Xing-FangLi,andX.ChrisLe.p-Azidophenylarsenoxide:AnArsenical"Bait"fortheInSituCaptureandIdentificationofCellularArsenic-BindingProteins.Angew.Chem.Int.Ed.,2016,55(45),14051-14056. 6.BirgetMoe,ChungangYuan,JinhuaLi,HaiyingDu,StephanGabos,X.ChrisLe,andXing-FangLi.Real-TimeCell-ElectronicSensingofCoalFlyAshParticulateMatterforToxicity-BasedAirQualityMonitoring.Chem.Res.Toxicol.,2016,29(6),972–980.(AmericanChemistrySociety(ACS)Editors'Choice) 7.WeiWang,BirgetMoe,JinhuaLi,YichaoQian,QiZheng,Xing-fangLi.Analyticalcharacterization,occurrence,transformation,andremovaloftheemergingdisinfectionbyproductshalobenzoquinonesinwater.TrendsAnal.Chem.,2016,85:97-110. 8.JinhuaLi,KatherineFu,SaiVemula,ChrisX.Le,andXing-FangLi.StudyingdevelopmentalneurotoxiceffectsofbisphenolA(BPA)usingembryonicstemcells.J.Environ.Sci.,2015,36,173-177. 9.JinhuaLi,WeiWang,BirgetMoe,HailinWang,andXing-FangLi.Chemicalandtoxicologicalcharacterizationofhalobenzoquinones,anemergingclassofdisinfectionbyproducts.Chem.Res.Toxicol.,2015,28(3):306-318.(EditorialAdvisoryBoardMembers’FavoriteCRTArticles) 10.JinhuaLi,WeiWang,HongquanZhang,X.ChrisLe,andXing-FangLi.GlutathionemediateddetoxificationofhalobenzoquinonedrinkingwaterdisinfectionbyproductsinT24cells.Toxicol.Sci.,2014,141(2):335-343. 11.WeiWang,YichaoQian,JinhuaLi,BirgetMoe,RongfuHuang,HongquanZhang,SteveE.Hrudey,andXing-FangLi.Analyticalandtoxicitycharacterizationofhalo-hydroxyl-benzoquinonesasstablehaloquinonedisinfectionbyproductsintreatedwater.Anal.Chem.,2014,86,4982-4988. 12.HaiyingDu,JinhuaLi,BirgetMoe,ClaireF.McGuiganandXing-FangLi.Areal-timecell-electronicsensingmethodforcomparativeanalysisoftoxicityofwatercontaminants.Anal.Methods,2014,6,2053-2058.(co-firstauthor) 13.JuanWang,XiaofengQu,YanfeiQi,JinhuaLi,XiulingSong,LiLi,DehuiYin,KunXu,andJuanLi.PharmacokineticsofAnti-HBVPolyoxometalateinRats.PLoSOne.2014;9(6):e98292. 14.HaiyingDu,JinhuaLi,BirgetMoe,ClaireF.McGuigan,ShengwenShen,andXing-FangLi.CytotoxicityandoxidativedamageinducedbyhalobenzoquinonestoT24bladdercancercells.Environ.Sci.Technol.,2013,47(6):2823-30.(co-firstauthor) 15.JiahuiWu,HongfangWang,ZhichengWang,KaiXu,YaliQi,JinhuaLi,ShouliangGongYangLiu,andYaLiu.Conditionallyreplicatingadenoviruscombinedwithgene-targetedradiotherapyinducesapoptosisviaTRAILdeathreceptorsinMDA-MB-231cells.MolecularMedicineReports,2013,8,299-305. 16.王宏芳,刘扬,李金华,吴嘉慧,李艳博,王志成,刘威武,龚守良.双重靶向条件复制型腺病毒的包装及抗肿瘤作用.西安交通大学学报(医学版),2013,34(3):308-312. 17.Yan-feiQi,HongZhang,JuanWang,YanfangJiang,JinhuaLi,YeYuan,ShiyaoZhang,KunXu,YangguangLi,JuanLi*,JunqiNiu,EnboWang.Invitroanti-hepatitisBandSARSvirusactivitiesofatitanium-substituted-heteropolytungstate.AntiviralResearch,2012,93(1):118-25. 18.原野,李金华,王娟,张士尧,鞠文,齐燕飞,李娟,徐坤.新型多酸化合物NCW-6的毒理学安全性评价.吉林大学学报(医学版),2012,38(1):28-32. 19.李金华,刘扬,王宏芳,王志成,吴嘉慧,龚守良,李娟.hTERT启动子调控的TRAIL基因表达载体的构建及其对肝癌细胞增殖的抑制作用.吉林大学学报(医学版),2010,36(5):825-831. 20.王宏芳,李金华,刘扬,李艳博,王志成,刘威武,龚守良.单重靶向条件复制型腺病毒穿梭载体pshuttle-E1A-E1Bp-E1B55K的构建及鉴定.吉林大学学报(医学版),2010,36(5):821-824. 21.王宏芳,李雪静,浦昀,李金华,徐坤,宋秀玲,李娟.松茸多糖对辐射损伤小鼠免疫功能的保护作用.西安交通大学学报(医学版),2010,31(3):388-390. 22.徐坤,李静,李金华,侯雷,杨松涛,王宏芳,浦昀,吴新宇,李娟,夏咸柱.金刚烷胺修饰物对禽流感病毒感染小鼠免疫功能的影响.吉林大学学报(医学版),2009,35(6):1011-1104. 著作教材: 1.刘林林,龚守良等,主编.恶性肿瘤生物治疗学.第1版.北京:人民军医出版社,2013.(校级规划教材,编者)(ISBN:978-7-5091-7151-6) 2.龚守良,主编.肿瘤基因放射治疗学基础.第1版.北京:人民军医出版社,2013.(专著,编者)(ISBN:978-7-5091-6698-7)

学术兼职

中华预防医学会卫生毒理分会青年委员 中国毒理学会会员 加拿大化学学会会员 美国毒理学会会员

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