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个人简介

讲授课程: 流行病学 预防医学 临床流行病学 现场调查技术 教育经历: 1986.09——1991.09白求恩医科大学预防医学院环境医学专业本科生,获得医学学士学位 1991.09——1994.07白求恩医科大学预防医学院卫生毒理学专业研究生,获得医学硕士学位 1999.09——2002.06吉林大学基础医学院生物化学与分子生物学专业研究生,获得理学博士学位 工作经历: 1994.07——1996.06白求恩医科大学预防医学院助教(1995.07) 1996.06——2001.09白求恩医科大学预防医学院讲师 2001.09——2006.09吉林大学公共卫生学院副教授 2006.09——2012.12吉林大学公共卫生学院教授 (2004.01——2008.01吉林大学基础医学流动站博士后) (2007.01——2008.01瑞典卡罗林斯卡大学公派访问学者) 2012.12——现在吉林大学公共卫生学院副院长、教授

研究领域

研究方向:分子遗传流行病学

科研项目: 1.HDL偏低人群循环miRNA差异表达与原发性高血压关系的研究(81573230)国家自然科学基金2016-2019 2.胼胝体投射神经元发育机制的合作研究(编号2015DFA31580)科技部国家国际合作专项2015.4-2018.3 3.羟基脂肪酸类雌激素受体调节物对阿尔兹海默病作用机制研究(编号20150101130JC)科技厅自然科学基金2015.01-2017 4.他莫昔芬抗性乳腺癌治疗中DNA甲基化状态的修正策略研究(20140413016GH)科技厅国际合作2014-2016 5.ERβ通过负性调控XBP1对抗ERα阳性乳腺癌细胞增殖的机制研究(2013102009)白求恩B计划2014-2016 6.雌激素受体及NCOA1基因环境交互作用与2型糖尿病关系的研究(200905185)省科技厅2009-2011 7.雌激素受体辅助因子FOXP1调节基因表达分子机制研究教育部留学回国人员启动基金2009-2011 8.基因组中雌激素受体β与FOXA1的DNA结合位点解析及其对下游基因的调控作用(30870952)国家自然科学基金2009-2011 9.雌激素受体-转录辅助因子复合体对乳腺癌细胞基因的调制研究(20080735)省科技厅2009-2011 10.吉林省卫生人力资源发展状况调查研究(2001I003)省卫生厅2011.07-2012.06 11.雌激素受体、RIP40基因与2型糖尿病易感性的关联研究(2001R009)省卫生厅2012.01-2014.12

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1.LiR1,LiW2,LunZ3,ZhangH4,SunZ5,KanuJS1,QiuS1,ChengY6,LiuY7.Prevalenceofmetabolicsyndromeinmainlandchina:ameta-analysisofpublishedstudies.BMCPublicHealth.2016Apr1;16(1):296.doi:10.1186/s12889-016-2870-y. 2.Yu,MX(Yu,Mingxi)[1];Liu,YW(Liu,Yawen)[1];Li,Y(Li,Yong)[1];Zhang,HP(Zhang,Huiping)[2];Lu,YP(Lu,Yuping)[1];Kanui,JS(Kanui,JosephSam)[1];Qiao,YC(Qiao,Yichun)[1];Tang,Y(Tang,Yuan)[1];Zhen,Q(Zhen,Qing)[1];Cheng,Y(Cheng,Yi)[3]EndotheliallipasegenepolymorphismsareassociatedwithserumHDL-Clevelsbutnotcoronaryheartdisease. 3.JosephSamKanu,YuluGu,SunZhi,MingxiYu,YupingLu,YetongCong,YunkaiLiu,YongLi,YaqinYu,YiCheng*andYawenLiu*.Singlenucleotidepolymorphismrs3774261intheAdipoQgeneisassociatedwiththeriskofcoronaryheartdisease(CHD)inNortheastHanChinesepopulation:acasecontrolstudy.LipidsHealthDis.2016Jan12;15(1):6.doi:10.1186/s12944-015-0173-4. 4.XinZhang,YuluGu,XiaoliLiu,YaqinYu,JiepingShi,QiongYu,HuiSun,JosephSamKanu,SiyanZhan*,andYawenLiu*.AssociationofPre-miR-146ars2910164PolymorphismwithPapillaryThyroidCancer.IntJEndocrinol.2015;2015:802562.doi:10.1155/2015/802562.Epub2015Nov18. 5.ZhijunLi,†,YanYao,†,YaqinYu,JiepingShi,YawenLiu,YuchunTao,ChangguiKou,HuipingZhang,WeiqingHan,YutianYin,LinglingJiangandBoLi*,PrevalenceandAssociatedFactorsofPassiveSmokingamongWomeninJilinProvince,China:ACross-SectionalStudy.IntJEnvironResPublicHealth.2015Oct30;12(11):13970-80.doi:10.3390/ijerph121113970. 6.MingxiYu†,SiameGilbert†,YongLi,HuipingZhang,YichunQiao,YupingLu,YuanTang,QingZhen,YiCheng*,YawenLiu*.AssociationofNCOA3polymorphismswithDyslipidemiaintheChineseHanpopulation.LipidsHealthDis.2015Oct9;14:124.doi:10.1186/s12944-015-0126-y 7.YupingLu,YawenLiu,YongLi,HuipingZhang,MingxiYu,JosephSamKanu,YichunQiao,YuanTang,QingZhen,YiCheng*.AssociationofATP-bindingcassettetransporterA1genepolymorphismswithplasmalipidvariabilityandcoronaryheartdiseaserisk.IntJClinExpPathol.2015Oct1;8(10):13441-9.eCollection2015. 8.YupingLu#,TsadikGhebreamlakHabtetsion#,YongLi,HuipingZhang,YichunQiao,MingxiYu,YuanTang,QingZhen,YiCheng*,YawenLiu*.AssociationofNCOA2genepolymorphismswithobesityanddyslipidemiaintheChineseHanpopulation.IntJClinExpPathol.2015;8(6):7341-7349 9.ZhijunLi,YanYao,WeiqingHan,YaqinYu,YawenLiu,YuchunTao,ChangguiKou,LinglingJiang,QingSun,YutianYin,HuipingZhangandBoLi*.SmokingPrevalenceandAssociatedFactorsaswellasAttitudesandPerceptionstowardsTobaccoControlinNortheastChina.Int.J.Environ.Res.PublicHealth2015,12,8606-8618. 10.DanLi,ZuojiaLiu,YeYuan,YawenLiu*.FenglanNiu*.Greensynthesisofgallicacid-coatedsilvernanoparticleswithhighantimicrobialactivityandlowcytotoxicitytonormalcells.ProcessBiochemistry.2015(50):357–366. 11.FanWang#,YawenLiu#,YetongCong,PengpengLi,YongLi,ZhihuiYan,YuanTang,YiCheng,YangZheng.Shiftoftheinterconnectionfromthereactionsystemofparaoxonase1totheperoxidationreactionsystemofmyeloperoxidasewithHDL-Clevels:Amarkerofatherosclerosisinpatientswithnormalcholesterollevels.ClinicaChimicaActa.2015(438):350-370. 12.Wang,S.,Kou,C.,Liu,Y.,Li,B.,Tao,Y.,D'Arcy,C.,Shi,J.,Wu,Y.,Liu,J.,Zhu,Y.,Yu,Y.Rural-UrbanDifferencesinthePrevalenceofChronicDiseaseinNortheastChina.Asia-PacificJournalofPublicHealth.2014. 13.HuipingZhang,FanWang,HongqinXu,YawenLiu,JinLiu,HongyuZhao,JoelGelernter.Differentiallyco‑expressedgenesinpostmortemprefrontalcortexofindividualswithalcoholusedisorders:influenceonalcoholmetabolism‑relatedpathways.HumGenet.2014.. 14.ChangWang,YaqinYu,XiangyangZhang,YongLi,ChangguiKou,BoLi,YuchunTao,QingZhen,HuanHe,JosephSamKanu,XufengHuang,MeiHan,YawenLiu*.Awareness,treatment,controlofdiabetesmellitusandtheriskfactors:surveyresultsfromnortheastchina.PLoSOne.2014Jul28;9(7):e103594.. 15.YingCheng,HuiLi,LixiaMa,ShuangZhang,ShiYan,JingZhu,ShengWang,RuiZhang,KaiNiuandYawenLiu.Detectionofc-kitmutationalstatusinsmall-celllungcancerinaChinesecohort.ThoracicCancer.2014May;5(3):225–231. 16.JosephSamKanu,YuanTang,YawenLiu*.AssessmentontheKnowledgeandReportedPracticesofWomenonMaternalandChildHealthinRuralSierraLeone:ACross-sectional.PLoSOne.2014Aug.28;9(8):e0105936 17.YuluGu,XiaoliLiu,YaqinYu,JiepingShi,LizheAi,HuiSun,JosephSamKanu,ChongWang,YawenLiu*.AssociationofATMgenepolymorphismwithPTCmetastasisinfemalepatients.InternationalJournalofEndocrinology.IntJEndocrinol.2014;2014:370825.doi:10.1155/2014/370825.Epub2014Oct16. 18.JingWu,Dan-DanWang,Xin-LouLi,SakeJdeVlas,Ya-QinYu,JianZhu,YingZhang,BoWang,LiYan,Li-QunFang,Ya-WenLiu*,Wu-ChunCao.IncreasingincidenceofhemorrhagicfeverwithrenalsyndromecouldbeassociatedwithlivestockhusbandryinChangchun,northeasternChina.BMCInfectDis.2014,14(301) 19.HuanHe,Ya-qinYu,YongLi,Chang-guiKou,BoLi,Yu-chunTao,QingZhen,ChangWang,JosephSamKanu,Xu-fengHuang,MeiHan,Ya-wenLiu*.Dyslipidemiaawareness,treatment,controlandinfluencefactorsamongadultsintheJilinprovinceinChina:across-sectionalstudy.LipidsHealthDis.2014,13(1):122. 20.Gu,Yulu,Yu,Yaqin,Ai,Lizhe,Shi,Jieping,Liu,Xiaoli,Sun,Hui,Liu,Yawen*.AssociationoftheATMgenepolymorphismswithpapillarythyroidcancer.Endocrine.2014,45(3):454-461. 21.Xu,Hongqin,Wang,Fan,Liu,Yawen,Yu,Yaqin,Gelernter,Joel,Zhang,Huiping.Sex-biasedmethylomeandtranscriptomeinhumanprefrontalcortex.HumanMolecularGenetics.2014,23(5):1260-1270. 22.Zhao,Chunyan,Gao,Hui,Liu,Yawen,Papoutsi,Zoi,Jaffrey,Sadaf,Gustafsson,Jan-Ake,Dahlman-Wright,Karin.Genome-WideMappingofEstrogenReceptor-beta-BindingRegionsRevealsExtensiveCross-TalkwithTranscriptionFactorActivatorProtein-1.CancerResearch,2010,70(12):5174-5183. 23.Liu,Yawen,Gao,Hui,Marstrand,TroelsTorben,Strom,Anders,Valen,Eivind,Sandelin,Albin,Gustafsson,Jan-Ake,Dahlman-Wright,Karin.ThegenomelandscapeofERalpha-andERbeta-bindingDNAregions.ProceedingsOfTheNationalAcademyOfSciencesOfTheUnitedStatesOfAmerica.2008,105(7):2604-2609. 24.GaoPujun,ShiYang,GaoYanhang,LiuYawen,TanYan.Thereceptorforbeta(2)GPIonmembraneofhepatocellularcarcinomacelllineSMMC-7721isannexinII.WorldJGastroenterol.2007;13(24):3364-8. 著作教材: 预防医学吉林大学出版社2012副主编 临床流行病学高等教育出版社2013编者 流行病学基础复旦大学出版社2011编者 流行病学协和医科大学出版社2017编者

学术兼职

中国抗癌协会肿瘤流行病学专业委员会第七届常务委员 吉林省预防医学会卫生应急分会第一届副主任委员 吉林省预防医学会第六届卫生检验专业委员会常务委员 吉林省预防医学会免疫规划专业委员会常务委员

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