杨学东 - 天津大学 - 药物科学与技术学院

个人简介

教育研究背景： 1979－1983 河北大学化学系学士（分析化学） 1996－2001 中国协和医科大学、中国医学科学院博士（天然药物化学） 2002－2003 清华大学化学系、分析中心博士后 2004 至今天津大学药物科学与技术学院副教授 2010－2011 美国麻省理工学院（MIT）生物工程系、化学系访问学者

研究领域

The research in the group of Yang involves the fields of natural products, medicinal chemistry and biochemistry research focused at the discovery and development of bioactive natural products and their analogs as clinical trials drug candidates. Work is carried out to understand the relationship between bioactive constituents and therapeutic effects of traditional Chinese medicine. Using basic natural products and medicinal chemistry principles coupled with modern technologies, including new analytical techniques, computational techniques, and mechanism of action or target-based medicinal chemistry research evaluation methods, the group works towards discovery and development of potential therapeutic drugs and functional foods.

近期论文

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Benzofuran ε-caprolactam glucosides, amides and phenylpropanoid derivatives with anti-inflammatory activity from Oxybaphus himalaicus Qiu Yan,Yang Xuedong,Xu Jun,Liu Bo,Li Xiaoxue Page:112905 ISSN:0031-9422 2021 Container-title:Phytochemistry Chemical Components and Antimicrobial Activities of Tea Tree Hydrosol and Their Correlation With Tea Tree Oil Natural Product Communications 2021-09 | Journal article DOI: 10.1177/1934578X211038390 CONTRIBUTORS: Xiaoxue Li; Dan Shen; Qiushuang Zang; Yan Qiu; Xuedong Yang Comprehensive quality evaluation of Lignum Caraganae and rapid discrimination of Caragana jubata and Caragana changduensis based on characteristic compound fingerprints by HPLC-UV and HPLC-MS/MS coupled with chemometrics analysis Qiulin Wang, Xun Wu, Xuedong Yang, Yi Zhang, Lina Wang, Xiaoxue Li, Yan Qiu First published: 23 June 2020 https://doi.org/10.1002/pca.2950 New hemiterpene and furolactone-type lignan glycosides from Securidaca inappendiculata Hassk Phytochemistry Letters 2020-06 | Journal article DOI: 10.1016/j.phytol.2020.04.001 CONTRIBUTORS: Can Yang; Zhi Wang; Yan Qiu; Haiyan Zha; Xuedong Yang Anti-inflammatory Chalcone–Isoflavone Dimers and Chalcone Dimers from Caragana jubata Journal of Natural Products 2019-10-25 | Journal article DOI: 10.1021/acs.jnatprod.9b00365 CONTRIBUTORS: Lina Wang; Xuedong Yang; Yi Zhang; Ruixue Chen; Yuanyuan Cui; Qiulin Wang Flavonoids from Mirabilis himalaica Li Xue,Yin Mingxia,Yang Xuedong,Yang Guang,Gao Xian Page:89-95 ISSN:0367-326X 2018 Container-title:Fitoterapia Zeolitic imidazolate framework-8 for selective extraction of a highly active anti-oxidant flavonoid from Caragana Jubata Journal of Chromatography A 2018-04 | Journal article DOI: 10.1016/j.chroma.2018.02.046 CONTRIBUTORS: Yuan-Yuan Cui; Cheng-Xiong Yang; Xue-Dong Yang; Xiu-Ping Yan Two new hemiterpene glycosides and one new phenolic glycoside from the roots of Securidaca inappendiculata Hassk Wang Zhi,Zha Haiyan,Yang Xuedong,Hu Licui,Zheng Wenfeng,Xu Lizhen Page:74-77 ISSN:1874-3900 2017 Container-title:Phytochemistry Letters 蝉翼藤根中木质素苷及蔗糖酯成分研究王芷杨学东査海燕郭丽娜沈丹徐丽珍杨世林中国中药杂志. 2017,42(12) DOI: 10.19540/j.cnki.cjcmm.20170308.003 Isoflavonoids and norneolignan from Caragana changduensis Guo Lina,Yang Xuedong,Sun Xiaodong,Wu Xun Page:32-35 ISSN:1874-3900 2017 Container-title:Phytochemistry Letters