个人简介
Education
Sep., 2002 – Jul., 2005 School of life sciences, Fudan University Ph.D. in Population Genetics
Sep., 1999 – Jul., 2002 School of life sciences, Yunnan University M.S. in Zoology
Sep., 1995 – Jul., 1999 Biology Department, Yunnan University B.S. in Biology
Work experience
Apr., 2006 – Apr., 2008 Stanford Research Institute International (SRI International), San Francisco, U.S.A.
Postdoctoral Fellow
Aug., 2008 – Nov., 2009 CAS-MPG partner institute for computational biology, Shanghai, China
Assistant Professor
Dec., 2009 – Dec., 2017 CAS-MPG partner institute for computational biology, Shanghai, China
Associate Professor
Jan., 2018 – Present Institutes of Biomedical Sciences, Fudan University, Shanghai, China
Principle Investigator, Computational Genetics group
研究领域
Genetic theory of human complex traits; Modeling dynamics of biological population; Evolutionary ecology of human pathogen
近期论文
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Xu, F., Wang, Y., Ling, Y., Zhou, C., Wang, H., Teschendorff, A.E., Zhao, Y., Zhao, H., He, Y., Zhang, G, and Yang Z. (2022). dbDEMC 3.0: Functional exploration of differentially expressed miRNAs in cancers of human and model organisms. Genomics, Proteomics & Bioinformatics.
Yang, Z., Xu, F., Xue, A., Lv, H., and He, Y. (2022). Degree of Freedom of Gene Expression in Saccharomyces cerevisiae. Microbiology Spectrum 10, e00838-21. .
Yang, Z., Xu, F., Li, H., and He, Y. (2021). Beyond samples: A metric revealing more connections of gut microbiota between individuals. Computational and Structural Biotechnology Journal 19, 3930–3937. .
Yang, Z., Xu, F., Wang, H., Teschendorff, A.E., Xie, F., and He, Y. (2021). Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation. EBioMedicine 68, 103399. .
Dong, H., Zhu, Y., Shen, Y., Xie, S., He, Y., and Lu, L. (2021). High prevalence of tryptophan-truncated S quasispecies in treatment-naïve chronic hepatitis B patients. Journal of General Virology 102, 001623. .
Huang, X., Wang, S., Jin, L., and He, Y. (2021). Dissecting dynamics and differences of selective pressures in the evolution of human pigmentation. Biology Open 10, bio056523. .
Li, H., Wang, S., Zhong, F., Bao, W., Li, Y., Liu, L., Wang, H., and He, Y. (2020). Age-dependent risks of incidence and mortality of COVID-19 in Hubei Province and other parts of China. Frontiers in Medicine 7, 190.
Mo, W., Wang, M., Zhan, R., Yu, Y., He, Y., and Lu, H. (2019). Kluyveromyces marxianus developing ethanol tolerance during adaptive evolution with significant improvements of multiple pathways. Biotechnology for Biofuels 12, 1–15. .