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个人简介

Education Experience: 2006 Ph. D. Tianjin University, CN Professional Experience: 1998-2004 lecturer Tianjin University 1996-1998 assistant Tianjin University 2004-今 associate professor Tianjin University

研究领域

The research in the group of Wang involves the design, synthesis, and biological activity evaluation of new compounds, with focus on industrialization of generic drugs, intermediates, and fine chemicals. Specific areas include 1) Design and synthesis of the Rho kinase inhibitor, 2) Design and synthesis of the PDE4 inhibitor, and 3) Design and synthesis of antihistamine drugs

近期论文

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Synthesis of Spiro[benzofuran‐2,2'‐benzo[b]thiophene]‐3,3'‐diones via PIDA/CuBr‐Mediated Spirocyclization European Journal of Organic Chemistry 2020-11-15 | Journal article DOI: 10.1002/ejoc.202001001 CONTRIBUTORS: Xuemin Li; Huiyuan Liang; Yaxin O Yang; Xi Wang; Jingran Zhang; Donghua Wang; Fengxia Sun; Yunfei Du Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A Qiao Li , Chen Zhuang , Donghua Wang , Wei Zhang , Rongxuan Jia , Fengxia Sun , Yilin Zhang , Yunfei Du Beilstein J. Org. Chem. 2019, 15, 2958–2965. https://doi.org/10.3762/bjoc.15.291 Cascade Synthesis of Benzothieno[3,2-b]indoles under Oxidative Conditions Mediated by CuBr and tert-Butyl Hydroperoxide Xiaoyuan Zhao, Qiao Li, Jun Xu, Donghua Wang, Daisy Zhang-Negrerie, and Yunfei Du* Cite this: Org. Lett. 2018, 20, 18, 5933–5937 Publication Date:September 13, 2018 https://doi.org/10.1021/acs.orglett.8b02614 Design, synthesis, immunocytochemistry evaluation, and molecular docking investigation of several 4-aminopyridine derivatives as potential neuroprotective agents for treating Parkinson’s disease Li Shulin,Wei Daiyan,Mao Zhuo,Chen Ligong,Yan Xilong,Li Yang,Dong Shengjie,Wang Donghua Page:63-75 ISSN:0045-2068 2017 Container-title:Bioorganic Chemistry An Efficient Method for Synthesis of Tofacitinib Citrate Zhi Shuang,Liu Dengke,Liu Ying,Liu Bingni,Wang Donghua,Chen Ligong Page:1259-1263 ISSN:0022-152X 2015 Container-title:Journal of Heterocyclic Chemistry A scalable and facile process for the preparation of N-(pyridin-4-yl) piperazine-1-carboxamide hydrochloride Daiyan Wei, Ligong Chen, Xilong Yan, Yang Li, Jianye Li and Donghua Wang Page:152-155 ISSN:1747-5198 2016 Container-title:Journal of Chemical Research A Facile Method for the Synthesis of Betrixaban Li Jianye,Chen Ligong,Yan Xilong,Li Yang,Wei Daiyan,Wang Donghua Page:524-526 ISSN:1747-5198 2015 Container-title:Journal of Chemical Research Design, Synthesis, and Biological Evaluations of Several Y-26732 Analogues Wang Xinran,Chen Ligong,Li Hang,Sun Changhai,Qi Haofei,Wang Donghua Page:1212-1218 ISSN:0022-152X 2014 Container-title:Journal of Heterocyclic Chemistry Synthesis and structure confirmation of the impurity in crude roflumilast product Sun Chang-hai,Lin Yan,Sun Meng,Wang Dong-hua,Chen Li-gong Page:245-250 ISSN:0922-6168 2013 Container-title:Research on Chemical Intermediates

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