个人简介
Education Experience:
2003-2006 Doctor of Philosophy Chemistry University of York, UK
1996-2000 Bachelor of Science Chemistry Hu'nan University
Professional Experience:
2007-2010 Postdoctorial Research Associate University of Sheffield and GlaxoSmithKlein
2010-2023 Associate Professor/Professor Tianjin University, China
Honors and Awards:
Teaching Award, HSP, Tianjin University, 2018
Thieme Chemistry Journal Award, 2017
Best Publication Award, HSP, Tianjin University, 2015
研究领域
1) Molecular design (Med Chem & Asymmetric Catalyst)
2) Drug discovery and development in neuroscience
3) Synthetic Methodology Development
近期论文
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A Ruthenium Arene Complex with Central, Planar and Axial Chirality
2023-10-25 | Preprint
DOI: 10.26434/chemrxiv-2022-j4lg4-v2
CONTRIBUTORS: Xuegang Fu; Yuting Yan; Siyu E; Jianhui Huang
Total synthesis N–H (+)-tetrahydro deoxycytisine and application in Pd-catalyzed hydroarylation of ketimine
2023-06-19 | Preprint
DOI: 10.26434/chemrxiv-2023-1524p
CONTRIBUTORS: Jianhui Huang; Guotao Lin; Yuting Yan; Omer Yasin; Yuhan Lu; Shihao Huang
In Silico Discovery of Small Molecule Modulators Targeting the Achilles’ Heel of SARS-CoV-2 Spike Protein
Wang Qing,Meng Fanhao,Xie Yuting,Wang Wei,Meng Yumin,Li Linjie,Liu Tao,Qi Jianxun,Ni Xiaodan,Zheng Sanduo,Huang Jianhui,Huang Niu
Page:252-265 ISSN:2374-7943 2023
Container-title:ACS Central Science
Construction of aziridine, azetidine, indole and quinoline-like heterocycles via Pd-mediated C–H activation/annulation strategies
Organic & Biomolecular Chemistry
2022 | Journal article
DOI: 10.1039/D1OB02146J
CONTRIBUTORS: Mengyu Qiu; Xuegang Fu; Peng Fu; Jianhui Huang
KOtBu/O2 Mediated Dehydrogenation of N‐Heterocycles, Alcohols
ChemistrySelect
2022-08-12 | Journal article
DOI: 10.1002/slct.202202338
CONTRIBUTORS: Xuegang Fu; Yue Wang; Liu Liu; Caifeng Li; Lin Huang; Jianhui Huang
Natural Product-Inspired Chiral Ligand Design: Aloperine and N-Substituted Aloperines-Induced Pd-Catalyzed Asymmetric Hydroarylation of Ketimines
The Journal of Organic Chemistry
2022-08-05 | Journal article
DOI: 10.1021/acs.joc.2c00554
CONTRIBUTORS: Xuegang Fu; Yuting Yan; Hexin Sun; Siying Li; Jianhui Huang
Sparteine Family: Privileged Chiral Ligands in Transition Metal Catalysis
Zhang Mingyu,Yan Yuting,Sun Hexin,Fu Xuegang,Huang Jianhui
Page:427-431 ISSN:1385-2728 2022
Container-title:Current Organic Chemistry
Carbon Chain Rupture: Base-Induced Radical C–C Bond Cleavage of Alkylbenzimidazoles
Xuegang Fu , Dongyang Guo , Yuting Yan , Timotius Marselo , Mingyu Zhang , Zhenghan Zhang , Siying Li , Jianhui Huang∗
Synthesis 2022; 54(20): 4481-4494
DOI: 10.1055/a-1883-1357
A Ruthenium Arene Complex with Central, Planar and Axial Chirality
2022-04-07 | Preprint
DOI: 10.26434/chemrxiv-2022-j4lg4
CONTRIBUTORS: Xuegang Fu; Yuting Yan; Siyu E; Jianhui Huang
Natural product inspired chiral ligand design: Aloperine induced asymmetric hydroarylation of ketimines under Pd catalysed conditions
2022-03-09 | Preprint
DOI: 10.26434/chemrxiv-2022-z90nh
CONTRIBUTORS: Xuegang Fu; Yuting Yan; Hexin Sun; Siying Li; Jianhui Huang
Mechanistic studies of Cp*Ir(iii)/Cp*Rh(iii)-catalyzed branch-selective allylic C–H amidation: why is Cp*Ir(iii) superior to Cp*Rh(iii)?
Organic & Biomolecular Chemistry
2021 | Journal article
DOI: 10.1039/D1OB00446H
CONTRIBUTORS: Nan Ma; Zheyuan Liu; Jianhui Huang; Yanfeng Dang
Structure, Function, and Pharmaceutical Ligands of 5-Hydroxytryptamine 2B Receptor
Pharmaceuticals
2021-01-20 | Journal article
DOI: 10.3390/ph14020076
CONTRIBUTORS: Qing Wang; Yu Zhou; Jianhui Huang; Niu Huang
Comparative toxicity analysis of corannulene and benzo[a]pyrene in mice
Li Gentao,Xiong Hui,Saeed Khawar,Ma Ruicong,Xing Yufeng,Bi Yajuan,Li Caiyu,Huang Jianhui,Zhang Youcai
Page:130-142 ISSN:0378-4274 2020
Container-title:Toxicology Letters
A New Scaffold for Molecular Design: The Preparative Scale-Syntheses of Ru- Centered Arene Compounds
Current Organic Chemistry
2020-08-11 | Journal article
DOI: 10.2174/1385272824999200608134129
CONTRIBUTORS: Siyu E; Jialin Liu; Yuting Yan; Xuegang Fu; Xueyan Huang; Fanyun Zeng; Fazal Malik; Jianhui Huang
Involvement of aryl hydrocarbon receptor in the cytotoxicity of corannulene and its derivatives
Li Gentao,Ma Ruicong,Xing Yufeng,Wei Jing,Bi Yajuan,Li Caiyu,Xiong Hui,Baldridge Kim K.,Huang Jianhui,Siegel Jay S.,Zhang Youcai
Page:114-121 ISSN:0378-4274 2020
Container-title:Toxicology Letters
Direct Double Arylation of Bridged Alkenes and Efficient Bis‐C–H Alkylation of Benzamides
ChemistrySelect
2018-07-31 | Journal article
DOI: 10.1002/slct.201801801
CONTRIBUTORS: Xiaoxia Zhao; Jinshan Bai; Fanyun Zeng; Yufeng Xing; Ranran Zhu; Jianhui Huang
Preparation of Thioanisole Biscarbanion and C–H Lithiation/Annulation Reactions for the Access of Five-Membered Heterocycles
Organic Letters
2018-06-01 | Journal article
DOI: 10.1021/acs.orglett.8b00850
CONTRIBUTORS: Ranran Zhu; Zheyuan Liu; Jie Chen; Xiaoyu Xiong; Yuntao Wang; Lin Huang; Jinshan Bai; Yanfeng Dang; Jianhui Huang