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个人简介

Education Experience: 1997-2002 Ph. D. Huazhong Agricultural University, CN 2002-2004 Postdoctoral Ocean University of China, CN Professional Experience: 2013- Professor Tianjin University 2004-2013 Associate Professor Tianjin University 2011-2012 Visiting scholar University of California, Berkeley 2002-2004 Postdoctoral fellow Ocean University of China Honors and Awards: 2018: Leader in Science and Technology Innovation of Tianjin City; 2015: The First Level of "131" Innovative Talent of Tianjin City 2013: Peiyang Talent Foundation of Tianjin University 2012: Peiyang Talent Foundation of Tianjin University (Young faculty) 2010: Excellent Women Faculty of Tianjin University 2009: Ten Outstanding Young People (Teacher) of Tianjin University 2008: Excellent Teacher of Tianjin University on Teaching and Education 2008: THIRD-GRADE AWARD in lecturing contest of youth teacher of Tianjin City 2004: Excellent Doctoral Dissertation of Huazhong Agricultural University

研究领域

The research of the Chen group concerns isolation, identification, bioactivity, and mechanism of constituents from natural resources. In particular, the group focuses on functional mechanism and structure-activity relationships of macromolecules (polysaccharides and proteins) as well as small biomolecules. Methods are being developed in the group to quantify bioactivity of polysaccharides and small biomolecules from Traditional Chinese Medicine and natural resources. Additionally, the group investigates functional food and new medicine from natural sources.

近期论文

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Phenylboronic Acid and Amino Bifunctional Modified Adsorbent for Quickly Separating Phenolic Acids from Crude Extract of Clerodendranthus spicatus and Evaluation of Their Antioxidant and Hypoglycemic Activities Molecules 2023-11 | Journal article | Author DOI: 10.3390/molecules28227539 CONTRIBUTORS: Mengqi Cheng; Qianyi Song; Xiaoyu Zhang; Pingyi Zheng; Ran Zhao; Youxin Li; Haixia Chen Isolation, structural characterization and cholesterol-lowering effects of a novel polysaccharide from mulberry (Morus alba L.) leaf Li Ruilin,Zhou Jingna,Zhang Xiaoyu,Zhang Tingting,Wang Jia,Zhang Min,He Chengwei,Chen Haixia Page:117010 ISSN:0926-6690 2023 Container-title:Industrial Crops and Products Construction of the Gal-NH2/mulberry leaf polysaccharides-lysozyme/luteolin nanoparticles and the amelioration effects on lipid accumulation Ruilin Li , Jingna Zhou , Xiaoyu Zhang , Yajie Wang , Jia Wang , Min Zhang , Chengwei He , Pengwei Zhuang , Haixia Chen International Journal of Biological Macromolecules Volume 253, Part 3, 31 December 2023, 126780 Gut microbiome-mediated glucose and lipid metabolism mechanism of star apple leaf polyphenol-enriched fraction on metabolic syndrome in diabetic mice Wang Yajie,Jia Yanan,Li Shuqin,Li Nannan,Zhou Jingna,Liu Junyu,Yang Shuyu,Zhang Min,Panichayupakaranant Pharkphoom,Chen Haixia Page:154820 ISSN:0944-7113 2023 Container-title:Phytomedicine A novel visualization method for the composition analysis of processed garlic by MALDI-TOF imaging mass spectrometry (MSI) and Q-TOF LC-MS/MS Li Nannan,Li Shuqin,Wang Qirou,Yang Shuyu,Hou Yinuo,Gao Yan,Zhang Xiangyang,Zhang Min,Chen Haixia Page:112746 ISSN:0963-9969 2023 Container-title:Food Research International Steam explosion improves extractability, antioxidant activity and α-glucosidase inhibitory activity of the constituents of Java tea (Clerodendranthus spicatus) Wang Jia,Zhang Xiaoyu,Liu Junyu,Li Ruilin,Zhou Jingna,Li Mingyue,Lu Jingyang,Zhao Guangyu,Li Xiang,Sui Wenjie,Zhang Min,Chen Haixia Page:103350 ISSN:1466-8564 2023 Container-title:Innovative Food Science & Emerging Technologies Li, S., Li, N., Wang, Y. et al. Structural Characterization of the Staphylococcus aureus Targeting Lectin Peptides from Garlic (Allium sativum L) by Liquid Nitrogen Grinding Coupled with the Proteomic and Antimicrobial Mechanism Analysis. Probiotics & Antimicro. Prot. (2023). https://doi.org/10.1007/s12602-023-10078-2 Compositional analysis and immunomodulatory activity of blue pigment fraction (BPF) from Laba garlic Li Nannan,Li Shuqin,Wang Yajie,Wang Qirou,Zhou Jingna,Liu Junyu,Gao Yan,Zhang Min,Chen Haixia Page:134976 ISSN:0308-8146 2023 Container-title:Food Chemistry Structural Characterization, Cytotoxicity, and the Antifungal Mechanism of a Novel Peptide Extracted from Garlic (Allium sativa L.) Molecules 2023-03 | Journal article | Author DOI: 10.3390/molecules28073098 CONTRIBUTORS: Shuqin Li; Yajie Wang; Jingna Zhou; Jia Wang; Min Zhang; Haixia Chen Studies on the key constituents and the related mechanisms of Clerodendranthus spicatus in the treatment of diabetes based on network pharmacology Wang Qirou,Li Nannan,Wang Yajie,Li Ruilin,Jia Yanan,Zhou Jingna,Liu Junyu,Zhang Min,Zhuang Pengwei,He Chengwei,Chen Haixia Page:115949 ISSN:0378-8741 2023 Container-title:Journal of Ethnopharmacology Biochemical Composition, Antioxidant Activity and Antiproliferative Effects of Different Processed Garlic Products Molecules 2023-01 | Journal article | Author DOI: 10.3390/molecules28020804 CONTRIBUTORS: Jingyang Lu; Nannan Li; Shuqin Li; Wei Liu; Mingyue Li; Min Zhang; Haixia Chen Preventive and synbiotic effects of the soluble dietary fiber obtained from Lentinula edodes byproducts and Lactobacillus plantarum LP90 against dextran sulfate sodium-induced colitis in mice Zihan Xue, Ruilin Li, Junyu Liu, Jingna Zhou, Xiaoyu Zhang, Tingting Zhang, Min Zhang, Yang Yang, Haixia Chen First published: 11 August 2022 https://doi.org/10.1002/jsfa.12173 Insight into the Progress on Natural Dyes: Sources, Structural Features, Health Effects, Challenges, and Potential Molecules 2022-05 | Journal article | Author DOI: 10.3390/molecules27103291 CONTRIBUTORS: Nannan Li; Qirou Wang; Jingna Zhou; Shuqin Li; Junyu Liu; Haixia Chen A Systematic Review of Orthosiphon stamineus Benth. in the Treatment of Diabetes and Its Complications Molecules 2022-01 | Journal article | Author DOI: 10.3390/molecules27020444 CONTRIBUTORS: Qirou Wang; Jia Wang; Nannan Li; Junyu Liu; Jingna Zhou; Pengwei Zhuang; Haixia Chen Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line Nutrients 2020-02 | Journal article | Author DOI: 10.3390/nu12020436 CONTRIBUTORS: Maria Giovanna Lupo; Noemi Biancorosso; Elisa Brilli; Germano Tarantino; Maria Pia Adorni; Greta Vivian; Marika Salvalaio; stefano dall'acqua; Stefania Sut; Cédric Neutel et al. Gao XD, Wang C, Chen ZQ, Chen Y, Santhanam R K, Xue ZH,Ma QQ, Guo QW, Liu W, Zhang M, Chen HX*. Effects of N-trans-feruloyltyramine isolated from laba garlic on antioxidant, cytotoxic activities and H2O2-induced oxidative damage in HepG2 and L02 cells. Food and Chemical Toxicology, 2019, 130, 130-141. Xue ZH, Chen Y, Jia YN, Wang YJ, Lu YP, Chen HX*, Zhang M*. Structure, thermal and rheological properties of different soluble dietary fiber fractions from mushroom Lentinula edodes (Berk.) Pegler residues. Food Hydrocolloids. Food Hydrocolloids,2019 ,95, 10-18 Guo QW, Xu LL, Chen Y, Ma QQ, Santhanam RK, Xue ZH, Gao XD, Chen HX*.Structural characterization of corn silk polysaccharides and its effect in H2O2 induced oxidative damage in L6 skeletal muscle cells. Carbohydrate Polymers. 2019, 208, 161-167 Chen ZQ ,Wang C, Gao XD , Chen Y, Santhanam R K ,Wang CL, Xu LL, Chen HX*. Interaction characterization of preheated soy protein isolate with cyanidin- 3-O-glucoside and their effects on the stability of black soybean seed coat anthocyanins extracts. Food Chemistry, 2019,271, 266–273 Guo QW, Chen ZQ, Santhanam RK, Xu LL, Gao XD, Ma QQ, Xue ZH, Chen HX*. Hypoglycemic effects of polysaccharides from corn silk (Maydis stigma) and their beneficial roles via regulating the PI3K/Akt signaling pathway in L6 skeletal muscle myotubes,International Journal of Biological Macromolecules, 2019, 121 , 981–988

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