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个人简介

教育经历 1985.09—1990.07 河北医学院临床医学本科生 1993.09—1996.06 北京中医药大学中西医结合基础硕士研究生 2000.09—2003.06 复旦大学中西医结合基础博士研究生 工作经历 1990.07—1991.06 河北省承德医学院, 局部解剖教研室, 助教 1991.07—2003.09 河北省承德医学院, 解剖教研室, 讲师 2005.03—2006.09 美国密苏里堪撒斯城大学药学院 访问学者 2003.10—2007.03 复旦大学, 基础医学院, 讲师 2007.04— 至今 复旦大学, 基础医学院, 副教授 获得奖项 2005, 上海市科技进步二等奖 2005, 中国中西医结合学会科技进步三等奖 2021 , 中国针灸学会科技进步一等奖 科研项目 2020,国家自然科学基金面上项目, NMDA受体信号通路及靶向NMDA受体的miRNAs参与电针调节围手术期下丘脑-垂体-肾上腺轴功能紊乱的机制, 主持 2016,国家自然科学基金面上项目, 下丘脑GABA A受体α亚基参与电针调节急性手术创伤HPA轴功能紊乱的神经机制, 主持 2013,国家自然科学基金面上项目,NKB/dynorphin参与kisspeptin/ GPR54 介导的滋阴泻火中药合剂治疗性早熟的神经机制, 主持 2010,国家自然科学基金面上项目,从kisspeptin/GPR54 信号通路探讨滋阴泻火中药合剂治疗性早熟的神经内分泌机制, 主持 2013,国家重点基础研究发展计划(973 计划)项目,针药复合麻醉机体保护机制研究,参研 2007,国家重点基础研究发展计划(973 计划)项目,基于针药复合麻醉颅脑手术的镇痛机理研究,参研 2010,国家自然科学基金面上项目,中药复方地黄方调控基底神经节环路缓解帕金森病异动症的研究 , 参研

研究领域

针刺及中药调节下丘脑-垂体-靶腺轴功能紊乱及相关疾病的神经生物学机制

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Yu Wang; Jing Han; Jing Zhu; Yueshan Du; Minda Ju; Zhanzhuang Tian; Mizhen Zhang; GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic- Pituitary-Adrenal Axis Hyperactivity, Frontiers in Neuroscience, 2021 Zhang Mizhen; Sun Jingxian; Wang Yu; Tian Zhanzhuang; Secretagogin Mediates the Regulatory Effect of Electroacupuncture on Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Surgical Trauma, Neural Plasticity, Volume 2021, Article ID 8881136, https://doi.org/10.1155/2021/8881136 Zhu, Jing; Chen, Zhejun; Meng, Zehui; Ju, Minda; Zhang, Mizhen; Wu, Gencheng; Guo, Haidong; Tian, Zhanzhuang; Electroacupuncture Alleviates Surgical Trauma- Induced Hypothalamus Pituitary Adrenal Axis Hyperactivity Via microRNA-142, Front. Mol. Neurosci, 10: 0-308, 2017 Minda Ju; Liu Yang; Jing Zhu; Zhejun Chen; Mizhen Zhang; Jin Yu; Zhanzhuang Tian; MiR-664-2 impacts pubertal development in a precocious-puberty rat model through targeting the NMDA receptor-1, Biology of Reproduction, 100(6): 1536-1548, 2019 Yan Sun, Jian Yu, Boying Chen , Zhanzhuang Tian. Effect of Nourishing ″Yin″- Removing ″Fire″ Chinese herb mixture on the hypothalamic kisspeptin expression in precocious rats. Journal of Ethnopharmacology, 127:274-279,2010 Jing Zhu, Zhejun Chen, Jinxing Tian, Zehui Meng, Minda Ju, GenCheng Wu and Zhanzhuang Tian. miR-34b attenuates trauma-induced anxiety-like behavior by targeting CRHR1. International Journal of Molecular Medicine 40: 90-100,2017 Jing Zhu, Zhejun Chen, LiTing Zhu, ZeHui Meng, GenCheng Wu, ZhanZhuang Tian. Arginine Vasopressin and Arginine Vasopressin Receptor 1b Involved in Electroacupuncture- Attenuated Hypothalamic- Pituitary- Adrenal Axis Hyperactivity in Hepatectomy Rats. Neuromodulation, 19: 498–506, 2016 Zhejun Chen, Zehui Meng, Shiran Wang, Liting Zhu, Zhanzhuang Tian. Effects of Nourishing “Yin”-Removing “Fire” Chinese Herb Mixture on the Expression of GABAB Receptors in Hypothalamus of Precocious Puberty Female Rats. Chinese Medicine, 7, 55-66. 2016 Shiran Wang, Liting Zhu, Jian Yu, Zhanzhuang Tian. Effect of Nourishing“Yin”-removing “Fire” Chinese herbal mixture on hypothalamic NKB/NK3R expression in female precocious rats. Evidence-Based Complementary and Alternative Medicine Article ID 217424, http://dx.doi.org/10.1155/2014/217424, 2014 Jing Li, Yanyan Sun, Shiran Wang, Jian Yu, Zhanzhuang Tian. Effects of Nourishing “Yin”-Removing “Fire” Chinese Herb Mixture on the Differential Expression of GABAA Receptor α Subunits in Hypothalamus of Precocious Puberty Female Rats. Chinese Medicine, 4, 87-96,2013

学术兼职

2015-今 中国针灸学会针刺麻醉分会 副秘书长

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