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个人简介

教育经历 2003.09-2008.06,复旦大学上海医学院生物化学与分子生物学系,博士 1998.09-2003.06,复旦大学上海医学院(原上海医科大学),本科 工作经历 2012.07-今,复旦大学基础医学院法医学系 2008.07-2012.06,复旦大学上海医学院生物化学与分子生物学系 获得奖项 2018,复旦大学第一三共制药奖教金

研究领域

疑难法医生物检材检测,发展新型检测方法技术、检测体系及检测结果解释算法,为疑难生物检材来源个体的个体识别提供策略 复杂亲缘关系鉴定, 发展新型检测体系和结果解释算法,为复杂亲缘关系鉴定及个体排查提供策略

近期论文

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法医STR变异规律和特征研究 Yang Q, Yao Y, Shao C, Zhou Y, Li H, Li C, Tang Q, Xie J*. Calculation of the Paternity Index for STR with tri-allelic patterns in paternity testing. Forensic Sci Int. 2021:110832. Yang Q, Shen Y, Shao C, Liu Y, Xu H, Zhou Y, Liu Z, Sun K, Tang Q, Xie J*. Genetic analysis of tri-allelic patterns at the CODIS STR loci. Mol Genet Genomics. 2020; 295(5):1263-68. Yang Q, Li M, Sun K, Wang Q, Shao C, Liu Y, Xu H, Zhang S, Bian Y*, Gao Y*, Li C*, Liu Y*, Xie J*. Genetic analysis of type 2 tri-allelic pattern at TPOX locus in the Chinese Han population. Mol Genet Genomics. 2020; 295(4):933-39. Yang Q, Liu B, Shao C, Zhou Y, Yao Y, Pan Y, Sun K, Xu H, Li C, Wei T, Zhou Y, Tang Q, Xie J*. Characterization of the extra copy of TPOX locus with tri-allelic pattern. BMC Genet. 2019; 20(1):18. Yao Y, Yang Q, Shao C, Liu B, Zhou Y, Xu H, Zhou Y, Tang Q, Xie J*. Null alleles and sequence variations at primer binding sites of STR loci within multiplex typing systems. Leg Med (Tokyo). 2018; 30:10-13. Shao C, Lin M, Zhou Z, Zhou Y, Shen Y, Xue A, Zhou H, Tang Q, Xie J*. Mutation analysis of 19 autosomal short tandem repeats in Chinese Han population from Shanghai. Int J Legal Med. 2016; 130(6):1439-44. 疑难生物检材检测策略研究 Yao Y, Sun K, Yang Q, Zhou Z, Shao C, Qian X, Tang Q, Xie J*. Assessing autosomal InDel loci with multiple insertions or deletions of random DNA Sequences in human genome. Front Genet. 2022; 12: 809815. Yang Q, Liu B, Zhou Y, Yao Y, Zhou Z, Li H, Shao C, Sun K, Xu H, Tang Q, Shen Y*, Xie J*. Evaluation of one-step RT-PCR multiplex assay for body fluid identification. Int J Legal Med. 2021; 135(5):1727-1735. Liu B, Yang Q, Meng H, Shao C, Jiang J, Xu H, Sun K, Zhou Y, Yao Y, Zhou Z, Li H, Shen Y, Zhao Z, Tang Q, Xie J*. Development of a multiplex system for the identification of forensically relevant body fluids. Forensic Sci Int Genet. 2020; 47:102312. Liu B, Song F, Yang Q, Zhou Y, Shao C, Shen Y, Zhao Z, Tang Q, Hou Y, Xie J*. Characterization of tissue-specific biomarkers with the expression of circRNAs in forensically relevant body fluids. Int J Legal Med. 2019; 133(5):1321-31. Sun K, Yun L, Zhang C, Shao C, Gao T, Zhao Z, Hou Y, Xie J*, Tang Q*. Evaluation of 12 Multi-InDel markers for forensic ancestry prediction in Asian populations. Forensic Sci Int Genet. 2019; 43:102155. Zhang Y, Liu B, Shao C, Xu H, Xue A, Zhao Z, Shen Y*, Tang Q, Xie J*. Evaluation of the inclusion of circular RNAs in mRNA profiling in forensic body fluid identification. Int J Legal Med. 2018; 132(1):43-52. 复杂亲缘关系鉴定研究 Zhou Z, Zhou Y, Li Z, Yao Y, Yang Q, Qian J, Shao C, Qian X, Sun K, Tang Q, Xie J*. Identification and assessment of a subset of Y-SNPs with recurrent mutation for forensic purpose. Forensic Sci Int. 2022; 334:111270. Zhou Z, Zhou Y, Yao Y, Qian J, Liu B, Yang Q, Shao C, Li H, Sun K, Tang Q, Xie J*. A 16-plex Y-SNP typing system based on allele-specific PCR for the genotyping of Chinese Y-chromosomal haplogroups. Leg Med (Tokyo). 2020; 46:101720. Zhou Y, Yao Y, Liu B, Yang Q, Zhou Z, Shao C, Li S, Tang Q, Xie J*. Characterizing Y-STRs in the Evaluation of Population Differentiation Using the Mean of Allele Frequency Difference between Populations. Genes (Basel). 2020; 11(5): 566. Zhou Y, Shao C, Li L, Zhang Y, Liu B, Yang Q, Tang Q, Li S, Xie J*. Genetic analysis of 29 Y-STR loci in the Chinese Han population from Shanghai. Forensic Sci Int Genet. 2018; 32:e1-e4.

学术兼职

上海司法鉴定协会法医物证专业 副主任委员 中国遗传学会法医遗传学分会 委员 中国法医学会法医物证专业 委员 上海市法医学会 理事 法医学杂志、Genes杂志 编委

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