个人简介
教育经历
1996.09—2000.09 兰州医学院
2000.09—2003.07 兰州大学药理系硕士研究生
2004.09—2007.07 复旦大学药理系博士研究生
工作经历
2003.07—2004.09 上海中医药大学教师
2007.07—至今 复旦大学基础医学院药理系教师(2014.07-2015.07 美国哈佛大学神经科学系国家公派访问学者)
获得奖项
2016年获得高等学校科学研究优秀成果奖二等奖
研究领域
嗜睡症、抑郁焦虑等疾病诱发的睡眠紊乱机制研究
失眠治疗药物开发
近期论文
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Wang, Z. #, Zhong, Y.H., #, Jiang, S. #, Qu, W.M. *, Huang, Z.L. * , Chen, C.R. * Case Report: Dysfunction of the Paraventricular Hypothalamic Nucleus Area Induces Hypersomnia in Patients. Front Neurosci. Mar 14;16:830474,2022
Zhong ,Y.H. #, Jiang, S. #, Qu, W.M. * , Zhang, W. * , Huang, Z.L. * , Chen, C.R. * Saikosaponin a promotes sleep by decreasing neuronal activities in the lateral hypothalamus. J Sleep Res. Apr;31(2):e13484, 2022.
Chen, C.R. *#, Zhong ,Y.H. #, Jiang, S. #, Xu W. #, Xiao L., Wang Z, Qu, W.M. *, Huang, Z.L. * . Dysfunctions of the paraventricular hypothalamic nucleus induce hypersomnia in mice. Elife. Nov 17;10:e69909,2021.
Chen, C.R. #, Sun, Y. #, Luo Y.J., Zhou X.Z., Zhao X., Qu, W.M. * , Huang, Z.L. * . Paeoniflorin promotes non-rapid eye movement sleep via A1 receptors. J Pharmacol Exp Ther, Jan;356(1):64-73, 2016.
Chen C.Y., Wei X.D.,Chen, C.R. * .3,4,5-trimethoxycinnamic acid, one of the constituents of Polygalae Radix exerts anti-seizure effects via GABAAergic systems in mice, Journal of Pharmacological Sciences. J Pharmacol Sci, Jul 28;S1347-8613(15)00141-3,2015.
Chen C.Y., Li W., Qu K.P., CR Chen *. Piperine exerts anti-seizure effects via the TRPV1 receptor in mice. The European Journal of Pharmacology,Aug 15;714(1-3):288-94,2013.
CR Chen, SR Yang, YY Liu, WM Qu, Y Urade, ZL Huang*.Roles of adrenergic ?1 and dopamine D1 and D2 receptors in the mediation of the desynchronization effects of modafinil in a mouse EEG synchronization model. Plos One, 2013 Oct 7;8(10):e76102.
Qu W.M., Yue X.F., Sun Y., Fan K., Chen C.R., Hou Y.P., Urade Y., Huang Z.L *. Honokiol Promotes Non-rapid Eye Movement Sleep via GABAA/benzodiazepine Receptors in Mice.Br J Pharmacol,Oct;167(3):587-98, 2012.
Chen, C.R. #, Zhou X.Z. #, Luo Y.J. #, Huang, Z.L. *, Urade, Y. *, Qu, W.M. * . Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABA(A) receptor in mice. Neuropharmacology. Nov;63(6):1191-9, 2012.
Chen, C.R. #, Tan,R. #, Qu, W.M. *, Wu,Z., Wang,Y., Urade, Y., Huang, Z.L. * . Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, exerts antiepileptic effects via the GABA/benzodiazepine receptor complex in mice. Br J Pharmacol. Nov; 164(5):1534-46, 2011.