个人简介
刘国元(1977~),博士,副教授。原上海医科大学法医学本科、复旦大学基础医学院病理学硕士、生命科学学院医学遗传学博士。现任基础医学院病理系副教授,参与本科生《病理解剖学》、《临床病理讨论》及研究生《现代组织化学》等课程。以第一作者和共同通讯作者身份共发表SCI论文共5篇(复旦大学为通讯单位),其中2篇表在国际著名刊物Hepatology上。以合作者发表SCI文章7篇。作为项目主持人承担国家自然科学基金项目共2项。
荣誉与获奖
2020年度教育部高等学校科学研究优秀成果奖(科学技术)二等奖(第二完成人)
2018年上海市医学会病理学术年会优秀论文奖。
2016年上海市医学会病理学术年会优秀论文奖
研究领域
新基因ZNF191、Cyclin Y参与肝癌发病机制研究
病理解剖临床分析研究
近期论文
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Zheng F, Liu G*, Dang T, Chen Q, An Y, Wu M, Kong X, Qiu Z*, Wu B*. GABA signaling pathway-associated gene PLCL1 Rare Variants may be associated with Autism Spectrum Disorders. Neurosci Bull. 2021 Aug;37(8):1240-1245.(SCI论文,IF: 5.203,共同通讯作者)
Liu Y, Wu D, Cheng H, Chen L, Zhang W, Zou L, Gao Q, Zhao Z, Chen Q, Zeng W, Zhang Z, Jiang W*, Huang C*, Liu G*. Wnt8B, transcriptionally regulated by ZNF191, promotes cell proliferation of hepatocellular carcinoma via Wnt signaling. Cancer Sci. 2021, 112(2): 629-640 (SCI论文,IF: 6.716,通讯作者))
Chen L, Wang X, Cheng H, Zhang W, Liu Y, Zeng W, Yu L, Huang C*, Liu G*. Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1162-1169. (SCI论文,IF: 3.575,通讯作者)
Liu D, Gan R, Zhang W, Wang W, Saiyin H, Zeng W, Liu G*, Autopsy interrogation of emergency medicine dispute cases:how often are clinical diagnoses incorrect? J Clin Pathol, 2018 Jan;71(1):67-71. (SCI论文, IF: 3.411,通讯作者)
Wu D, Liu G*, Liu Y, Saiyin H, Wang C, Wei Z, Zeng W, Liu D, Chen Q, Zhao Z, Zou L, Huang H*, Jiang S*, Yu L*. Zinc finger protein 191 inhibits hepatocellular carcinoma metastasis through discs large 1-mediated yes-associated protein inactivation. Hepatology, 2016 Oct;64(4):1148-1162. (SCI论文I区, IF: 17.425,共同通讯作者)
Liu G, Jiang S, Wang C, Jiang W, Liu Z, Liu C, Saiyin H, Yang X, Shen S, Jiang D, Zhou P, Han D, Hu X, Yi Q, Yu L*. Zinc finger transcription factor 191,directly binding to β-catenin promoter, promotes cell proliferation of hepatocellular carcinoma. Hepatology. 2012 Jun;55(6):1830-9. (SCI论文I区, IF: 17.425)
Liu GY, Jiang DK, Shen SQ, Yu L. MDM2 SNP309T>G polymorphism with hepatocellular carcinoma risk: a meta-analysis. Arch Med Res. 2011 Feb;42(2):149-55. (SCI, IF: 2.235 )
Liu G, Jiang D, Shen S, Yu L. Murine double minute 2 promoter SNP309 polymorphism and prostate cancer risk: A meta-analysis. Int J Urol. 2012 Oct;19(10):914-20. (SCI, IF:3.369).
Liu G, Li G, Xu Y, Song N, Shen S, Jiang D, Zeng W, Wang H. Associationbetween IL12B polymorphisms and tuberculosis risk: a meta-analysis. Infect Genet Evol. 2014 Jan; 21:401-7. (SCI, IF: 3.342).
徐晨悦,甘荣昌,张志刚,刘国元*。母亲为Rh阴性血型的重度新生儿溶血症尸检一例。中华病理学杂志, 2019;August,48(8):645-647(通讯作者)
学术兼职
2020-今 中华医学会病理学分会(第十三届)心血管疾病学组委员
2016-今 全国卫生产业企业管理协会实验医学专家委员会病理专业委员会委员