瞿涤 - 复旦大学 - 基础医学院

个人简介

瞿涤研究员。实验室副主任，博士生导师。1988年获上海医科大学微生物学博士学位；1995年获里昂第一大学人类遗传学系病毒学专业博士学位；1994－1996年在美国FoxChaseCancerCenter做博士后。2000－2001年在美国Emory大学进修。中国微生物学会微生物学与免疫学专业委员会委员，中华医学会微生物学与免疫学分会委员，微生物与感染杂志副主编。

研究领域

研究方向为表皮葡萄球菌生物膜形成相关基因及其调控机制，在此基础之上发现抗菌或抗细菌生物膜的药物靶标，研发具有抗细菌生物膜的化合物以及抗微生物免疫

近期论文

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Lin Z, Cai X, Chen M, Ye L, Wu Y, Wang X, Lv Z, Shang Y, Qu D*. Virulence and Stress Responses of Shigella flexneri Regulated by PhoP/PhoQ. Front Microbiol. 2018, 8:2689. doi: 10.3389/fmicb. Bai J, Zhu X, Zhao K, Yan Y, Xu T, Wang J, Zheng J, Huang W, Shi L, Shang Y, Lv Z, Wang X, Wu Y*, Qu D*. The role of ArlRS in regulating oxacillin susceptibility in methicillin-resistant Staphylococcus aureus indicates it is a potential target for antimicrobial resistance breakers. Emerg Microbes Infect. 2019;8(1):503-515. doi: 10.1080/22221751. Zheng JX, Sun X, Lin ZW, Qi GB, Tu HP, Wu Y, Jiang SB, Chen Z, Deng QW*, Qu D*, Yu ZJ*. In vitro activities of daptomycin combined with fosfomycin or rifampin on planktonic and adherent linezolid-resistant isolates of Enterococcus faecalis. J Med Microbiol. 2019, 68(3):493-502. doi: 10.1099/jmm. Zheng JX, Chen Z, Xu ZC, Chen JW, Xu GJ, Sun X, Yu ZJ, Qu D*. In vitro evaluation of the antibacterial activities of radezolid and linezolid for Streptococcus agalactiae. Microb Pathog. 2020;139:103866. doi: 10.1016 Yongpeng Shang†, Xiaofei Wang†, Zhong Chen†, Zhihui Lyu, Zhiwei Lin, Jinxin Zheng, Yang Wu, Qiwen Deng, Zhijian Yu*, Ying Zhang* and Di Qu* Staphylococcus aureus PhoU Homologs Regulate Persister Formation and Virulence. Front. Microbiol. 26 May 2020 | https://doi.org/10.3389/fmicb.2020.00865 Jinxin Zheng†, Zhong Chen†, Zhiwei Lin†, Xiang Sun†, Bing Bai, Guangjian Xu, Junwen Chen, Zhijian Yu2* and Di Qu1* . Radezolid Is More Effective Than Linezolid Against Planktonic Cells and Inhibits Enterococcus faecalis Biofilm Formation. Front. Microbiol., 14 February 2020 | https://doi.org/10.3389/fmicb.2020.00196 Zhihui Lyu, Yongpeng Shang, Xiaofei Wang, Yang Wu, Jinxin Zheng, Huayong Liu, Ting Gong, Lina Ye and Di Qu*. Monoclonal Antibodies Specific to the Extracellular Domain of Histidine Kinase YycG of Staphylococcus epidermidis Inhibit Biofilm Formation. Front. Microbiol., 07 August 2020 | https://doi.org/10.3389/fmicb.2020.01839. Zhiping Sun, Xia Cai, Chenjian Gu, Rong Zhang, Wendong Han, Yun Qian, Yuyan Wang, Wei Xu, Yang Wu, Xunjia Cheng, Zhenghong Yuan*, Youhua Xie* & Di Qu*. Survival of SARS-COV-2 under liquid medium, dry filter paper and acidic conditions. Cell Discovery volume 6, Article number: 57 (2020)

学术兼职

中国实验动物学会动物生物安全专业委员会主任委员《微生物与感染》杂志主编