张进 - 复旦大学 - 基础医学院

个人简介

教育经历 2005/9 - 2009/1，复旦大学，分子医学，博士 2002/9 - 2005/7，四川农业大学与军事医学科学院生物工程研究所（联合培养，四川农大授位），生化与分子生物学，硕士 1998/9 - 2002/7，青岛农业大学，动物科学，学士工作经历 2009/4 - 至今，复旦大学，基础医学院，副教授 2011/7-2012/4, Indiana University School of Medicine,博后 2010/12-2011/7, Emory University School of Medicine,博后科研项目负责人。国自然面上项目。81571472，纯合失活致死基因ZFHX4对脑发育的影响及机制研究，2016/01-2019/12，60万元负责人。国自然应急项目。81741085，81741085，PARD3基因在腭裂中的突变及机制研究，2018.01-2018.12，20万负责人。国自然青年基金。81100115，miR424及miR424*在法洛氏四联症发病中的角色及其作用机制研究，2012/01-2014/12，23万元负责人。教育部博士点基金。20110071120033，法洛氏四联症相关基因miR424及miR424*表达上调对小鼠心脏发育及功能的影响，2012/01-2014/12，5万元

研究领域

肺癌组织中，CD8+ T细胞与肿瘤细胞间的交互调控原发性免疫缺陷的基因功能研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Cui, R., N. Jiang, M. Zhang, S. Du, H. Ou, R. Ge, D. Ma and J. Zhang*. AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells.' Biochim Biophys Acta Mol Cell Res 2020, 1868(1): 118858. Zhang M, Jiang N, Cui R, Du S, Ou H, Chen T, Ge R, Ma D*, Zhang J*: Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout. J Cell Mol Med 2019, 23(10):6978-6988. Zhang, M., Du, S., Ou, H., Cui, R., Jiang, N., Lin, Y., Ge, R., Ma, D.*, and Zhang, J*. Ablation of Zfhx4 results in early postnatal lethality by disrupting the respiratory center in mice, J Mol Cell Biol, 2021. doi: 10.1093/jmcb/mjaa081. Online ahead of print. Sichen Du; Huayuan Ou ; Renjie Cui; Nan Jiang; Meiqin Zhang; Xiaorong Li; Jing Ma; Jin Zhang *; Duan Ma*, Delivery of Glucosylceramidase Beta Gene Using AAV9 Vector Therapy as a Treatment Strategy in Mouse Models of Gaucher Disease , Human Gene Therapy, 2018.10.16, 30(2): 155~167 Wang, Jiping ; Xiao, Jiajun; Wen, Danping; Wu, Xie; Mao, Zuohua; Zhang, Jin *; Ma, Duan *, Endothelial cell-anchored tissue factor pathway inhibitor regulates tumor metastasis to the lung in mice, Molecular Carcinogenesis, 2016.5, 55(5): 882~896 Xu F, Wang YL, Chang JJ, Du SC, Diao L, Jiang N, Wang HJ, Ma D, Zhang J*. Mammalian sterile 20-like kinase 1/2 inhibits the Wnt/beta-catenin signalling pathway by directly binding casein kinase 1epsilon. The Biochemical journal. 2014, 458(1):159-169. Jin Zhang#, Jiao-Jiao Chang, Fei Xu, Xiao-Jing Ma, Yao Wu, Wen-Chan Li, Hui-Jun Wang, Guo-Ying Huang, Duan Ma. miRNA Deregulation in Right Ventricular Outflow Tract Myocardium of Non-syndromic Tetralogy of Fallot. Canadian Journal of Cardiology. 2013, 29(12):1695-703. Chen Y, Zhang J#, Wang H, Zhao J, Xu C, Du Y, Luo X, Zheng F, Liu R, Zhang H* and Ma D*. miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. BMC Cancer. 2012, 12:1-11.

学术兼职

2018-今上海医学遗传学会委员 2019-今中国妇幼保健协会儿童疾病和保健分会遗传代谢病与保健学组委员