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个人简介

教育经历 2005-2009 复旦大学 博士 2001-2005 复旦大学 硕士 1996-2000 复旦大学 药理学 学士 工作经历 2014年-今 复旦大学基础医学院细胞与遗传学系 副研究员 2013-今 哈佛大学医学院附属布里根妇女医院 访问学者 2009-2013 复旦大学 表观遗传学研究室 讲师 2006-2009 复旦大学基础医学院分子遗传实验室 讲师 2000-2006 复旦大学基础医学院分子遗传实验室 助教

研究领域

细胞分化与重编程中的表观遗传学机制 DNA甲基化/羟甲基化与组蛋白修饰之间的交互作用

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ER alpha-positive breast cancer cells .Epigenetics .2021 METTL3 regulates heterochromatin in mouse embryonic stem cells .NATURE .2021 ,591 (7849) :317-321 DIFFERENTIATION OF MOUSE AND HUMAN EMBRYONIC STEM CELLS TO HEPATOCYTES INDUCED BY COMBINATION OF CYTOKINES AND SODIUM BUTYRATE .Journal of Hepatology .2009 ,50 :S315 Reduction of DNA hydroxymethylation in the mouse kidney insulted by ischemia reperfusion .BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS .2012 ,422 (4) :697-702 谭理. 乳腺癌组织中TET2突变与5hmC表达的关系 .中国临床医学 .2015 (1) :1-4 经Flk1前祖细胞胚胎干细胞分化为内皮细胞的研究 Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer Ten-eleven translocation methyl-cytosine dioxygenase 2 deficiency exacerbates renal ischemia-reperfusion injury Trans-2-phenylcyclopropylamine induces nerve cells apoptosis in zebrafish mediated by depression of LSD1 activity The effects of BHC80 down regulation on embryonic erythropoiesis in Zebrafish [The effects of BHC80 down regulation on embryonic erythropoiesis in Zebrafish] DNA羟甲基化在小鼠胚胎干细胞中的研究进展 Tet family proteins and 5-hydroxymethylcytosine in development and disease Pleiotropy of Glycogen Synthase Kinase-3 Inhibition by CHIR99021 Promotes Self-Renewal of Embryonic Stem Cells from Refractory Mouse Strains Genome-wide comparison of DNA hydroxymethylation in mouse embryonic stem cells and neural progenitor cells by a new comparative hMeDIP-seq method Targeted Knockdown of RNA-Binding Protein TIAR for Promoting Self-Renewal and Attenuating Differentiation of Mouse Embryonic Stem Cells A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming LanCL1 protects prostate cancer cells from oxidative stress via suppression of JNK pathway PD-L1基因表达的调控机制

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