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个人简介

教育经历 2002.09—2006.07 西安交通大学生命科学本科生 2006.09—2008.07 西安交通大学生物化学与分子生物学硕士研究生 2008.08—2013.12 美国密西根州立大学生物化学与分子生物学博士研究生 工作经历 2014.01—2015.12 美国芝加哥大学医学院博士后 2018.01—2019.01 美国伊利诺伊大学芝加哥分校医学院助理研究员 2019.04—至今 复旦大学基础医学院副研究员 获得奖项 2013,美国密西根州立大学博士论文奖,美国密西根州立大学

研究领域

癌基因/抑癌基因及融合基因及其信号转导通路在恶性肿瘤包括肝细胞肝癌、胰腺癌、非小细胞肺癌等发生发展中的作用;细胞蛋白质稳态的调节及在恶性肿瘤发生发展中的作用;肿瘤免疫微环境,慢性炎症在肿瘤发生发展中的作用

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Gao, S., Li, A-M, Liu, F., Chen, F., Williams, MR., Zhang, C-L, Kelly Z, Wu, CL, Luo R-C, Xiao H. Ncoa5 Haplo-insufficiency Results in Glucose Intolerance and Hepatocellular Carcinoma. Cancer Cell 24 (6), 725–737, 9 December, 2013 Kai Hou, Jianliang Shen, Junrong Yan, Chuannan Zhai, Jingxia Zhang, Ji-An Pan,Ye Zhang, Yaping Jiang, Yongbo Wang, Richard Z. Ling, Hongliang Cong*, Shenglan Gao*, Wei-Xing Zong.* Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin. EBioMedicine, 69,103456, 2021 Dipti Athavale, Zhuolun Song, Romain Desert, Hui Han, Sukanta Das, Xiaodong Ge, Sai Santosh Babu Komakula, Wei Chen, Shenglan Gao, Daniel Lantvit, Grace Guzman, Natalia Nieto. Ablation of high-mobility group box-1 in the liver reduces hepatocellular carcinoma but causes hyperbilirubinemia in Hippo signaling-deficient mice. Hepatol Commun. doi: 10.1002/hep4.1943. Mar 28, 2022. Fang Wang#, Ye Zhang#, Jianliang Shen, Bin Yang, Weiwei Dai, Junrong Yan, Sara Maimouni, Heineken Q. Daguplo, Sara Coppola,Yingtang Gao,Yijun Wang, Zhi Du,Kesong Peng, Hui Liu, Qin Zhang, Fei Tang, Peng Wang, Shenglan Gao, Yongbo Wang, Wen-Xing Ding, Grace Guo, Fengmei Wang, and Wei-Xing Zong. The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-Keap1-Nrf2 Antioxidant Pathway. Cellular and Molecular Gastroenterology and Hepatology, Volume 11, Issue 5, 2021, Pages 1369-1385, 2021 Shenglan Gao, Yueqi Zhang, Chengfeng Yang, Gloria I. Perez, Hua Xiao* NCOA5 Haplo-insufficiency Results in Male Mouse Infertility through Increased IL-6 Expression in the Epididymis. Scientific Reports, 9:15525, 2019 Liu, X.*, Liu, F.*, Gao, S., Reske J., Li A-M, Wu CL., Yang, C., Luo, R-C, and Xiao, H. A missense NCOA5 variant in type 2 diabetic patients with hepatocellular carcinoma impairs the function of NCOA5 in cell cycle regulation. Cancer Letters 391,152-161, 2017/4/10, 2017 Chen, F, Li. A, Gao, S., Hollern, D., VanSickle EA, Williams MR, Andrechek E., Zhang C-L, Yang C., Luo R., and Xiao, H (2014). Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression. Cell Death and Disease 5, e1242; doi:10.1038/cddis, 2014 Li, A-M, Zhang, C-L, Gao, S., Luo R-C, Xiao, H. TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice. Oncogene 32 (18), 2273-2281, 25 June 2012 Zhang, C-L, Mori, M., Gao, S., Li, A-M., Hoshino, I., Aupperlee, M.D., Haslam, S. Z., and Xiao, H, (2010). Tip30 Deletion in MMTV-Neu Mice Leads to Enhanced EGFR Signaling and Development of Estrogen Receptor-Positive and Progesterone Receptor-Negative Mammary Tumors. Cancer Research 70:10224-10233,15 December, 2010 Zhang, C-L, Li, A-M, Gao, S., Zhang, X, Xiao, H, (2011). The TIP30 Protein Complex, Arachidonic acid and Coenzyme A are Required for Vesicle Membrane Fusion. PLoS ONE 6 (6): e21233, 2011

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