个人简介
招生专业
070103-概率论与数理统计
071101-系统理论
071400-统计学
招生方向
计算与系统生物学
统计学,数据科学
机器学习
教育背景
2003-09--2009-07 北京大学 理学博士
1999-09--2003-07 南京大学 理学学士
工作简历
2014-03~现在, 中国科学院数学与系统科学研究院, 副研究员
2011-08~2014-02,中国科学院数学与系统科学研究院, 助理研究员
2009-04~2011-08,中国科学院数学与系统科学研究院, 博士后
教授课程
系统估计
概率论与数理统计
概率论与数理统计习题课-02
概率论与数理统计习题课-01
奖励信息
(1) APBC2019国际会议最佳论文, 特等奖, 其他, 2019
(2) Early Career Award, 研究所(学校), 2016
(3) 关肇直青年研究奖, 研究所(学校), 2014
(4) 中国科学院数学与系统科学研究院优秀教师奖, 研究所(学校), 2014
专利成果
( 1 ) 用于多个分子信号的数据处理方法与装置, 发明, 2018, 第 3 作者, 专利号: ZL201510061908.8
科研项目
( 1 ) 动物复杂形状的进化解析与调控, 参与, 部委级, 2014-07--2019-06
( 2 ) 中国科学院青年创新促进会, 主持, 部委级, 2016-01--2019-12
( 3 ) 生物/医学时空型数据的建模、计算与系统综合研究, 主持, 国家级, 2016-01--2019-12
( 4 ) 重大脑精神疾病的遗传影像学分析理论与计算方法, 参与, 国家级, 2017-01--2019-12
( 5 ) 非完整、异构材料数据关联统计分析与挖掘技术, 参与, 国家级, 2018-07--2022-06
近期论文
查看导师新发文章
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(1) RobustClone: A robust PCA method for tumor clone and evolution inference from single-cell sequencing data, Bioinformatics, 2020, 通讯作者
(2) Unsupervised Topological Alignment for Single-Cell Multi-Omics Integration, Bioinformatics, 2020, 通讯作者
(3) A branch point on differentiation trajectory is the bifurcating event revealed by dynamical network biomarker analysis of single-cell data, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2020, 通讯作者
(4) DensityPath: an algorithm to visualize and reconstruct cell state-transition path on density landscape for single-cell RNA sequencing data, Bioinformatics, 2019, 通讯作者
(5) Statistical test of structured continuous trees based on discordance matrix, Bioinformatics, 2019, 通讯作者
(6) TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data, BMC Genomics, 2019, 通讯作者
(7) Statistical testing and power analysis for brain-wide association study, Medical Image Analysis, 2018, 第 2 作者
(8) A remark on copy number variation detection methods, PLoS ONE, 2018, 通讯作者
(9) Functional connectivity decreases in autism in emotion, self, and face circuits identified by Knowledge-based Enrichment Analysis, NeuroImage, 2017, 第 6 作者
(10) An adaptive decorrelation method removes Illumina DNA base-calling errors caused by crosstalk between adjacent clusters, Scientific Reports, 2017, 第 2 作者
(11) Individual differences in schizophrenia, British Journal of Psychiatry Open, 2017, 第 3 作者
(12) Estimating Phred scores of Illumina base calls by logistic regression and sparse modeling, BMC Bioinformatics, 2017, 第 3 作者
(13) Individual differences in schizophrenia, British Journal of Psychiatry Open, 2017, 第 3 作者
(14) Achieving Accurate and Fast Base-calling by a Block Model of the Illumina Sequencing Data, IFAC-PapersOnLine, 2015, 第 2 作者
(15) Tracking the Evolving Spatial-Temporal Gene Networks, IFAC-PapersOnLine, 2015, 通讯作者
(16) 应用全基因组拷贝数变异方法探索参芪膜肾方治疗特发膜性肾病基因水平机制的研究, 中国中西医结合肾病杂志, 2014, 通讯作者
(17) Modeling RNA degradation for RNA-Seq with applications, Biostatistics, 2012, 第 1 作者
(18) CEDER: Accurate detection of differentially expressed genes by combining significance of exons using RNA-Seq, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2012, 第 1 作者
(19) Hybridization and amplification rate correction for affymetrix SNP arrays, BMC Medical Genomics, 2012, 通讯作者
(20) A study of biases of DNA copy number estimation based on PICR model, Frontiers of Mathematics in China, 2011, 通讯作者
(21) RseqFlow: Workflows for RNA-Seq data analysis, Bioinformatics, 2011, 第 9 作者
(22) New powerful statistics for alignment-free sequence comparison under a pattern transfer model, Journal of Theoretical Biology, 2011, 第 1 作者
(23) Alignment-free sequence comparison (II): Theoretical power of comparison statistics, Journal of Computational Biology, 2010, 第 1 作者
(24) The biases of copy numbers from Affymetrix SNP arrays and their corrections, Communications in Information and Systems, 2010, 第 1 作者
(25) Hybridization modeling of oligonucleotide SNP arrays for accurate DNA copy number estimation, Nucleic Acids Research, 2009, 第 1 作者
(26) Nonlinear cooperation between p53 and ING1 induces bax expression in mouse thymocyte apoptosis: A quantitative approach with cross-platform validation, Apoptosis, 2009, 第 1 作者
(27) Searching for bidirectional promoters in Arabidopsis thaliana, BMC Bioinformatics, 2009, 第 2 作者
(28) Conservation and implications of eukaryote transcriptional regulatory regions across multiple species, BMC Genomics, 2009, 第 1 作者
(29) Relaxation dynamics and glass transition in glassy materials, Synthetic Metals, 2003, 第 3 作者
学术兼职
2015-01-01-今,中国运筹学会计算系统生物学分会, 理事