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1.TianyuHan,WeihuaZhan,MingxiGan,FanrongLiu,BentongYu,Y.Eugene
Chin&Jian-BinWang*.PhosphorylationofglutaminasebyPKCεisessentialfor
itsenzymaticactivityandcriticallycontributestotumorigenesis.
CellResearch(2018)28:655–669;IF：15.6
2.TianyuHan,MengGuo,MingxiGan,BentongYu,XiaoliTian&Jian-BinWang*.
TRIM59regulatesautophagythroughmodulatingboththetranscriptionandthe
ubiquitinationofBECN1.Autophagy(2017).Accepted，IF：11.1
3.WeihuaZhan,WenjuanWang,TianyuHan,CaifengXie,TingtingZhang,Mingxi
Gan,Jian-BinWang.COMMD9promotesTFDP1/E2F1transcriptionalactivity
viainteractionwithTFDP1innon-smallcelllungcancer.CellularSignalling
(2017)，30:59-66.
4.TianyuHan,MengGuo,TingtingZhang,MingxiGan,CaifengXie,Jian-Bin
Wang.Anovelglutaminaseinhibitor-968inhibitsthemigrationandproliferation
ofnon-smallcelllungcancercellsbytargetingEGFR/ERKsignalingpathway.
Oncotarget(2017)Apr25;8(17):28063–28073.
5.Guan,X.H.,X.Hong,N.Zhao,X.H.Liu,Y.F.Xiao,T.T.Chen,L.B.Deng,X.L.
Wang,J.B.Wang,G.J.Ji,M.Fu,K.Y.Deng,andH.B.Xin,CD38promotes
angiotensinII-inducedcardiachypertrophy.JCellMolMed(2017)
6.CaifengXie,ZhenChen,ChengfuZhang,XinXu,JiangboJin,Weihua
Zhan,TianyuHan,Jian-BinWang*.Dihydromyricetinamelioratesoleic
acid-inducedlipidaccumulationinL02andHepG2cellsbyinhibitinglipogenesis
andoxidativestress.LifeSciences(2016),157:131–139.
7.CaifengXie,XujieBao,Wei-HuaZhan,Tian-YuHan,MingxiGan,Chengfu
Zhang,Xiao-JianHanandJian-BinWang*.Anovelglutaminaseinhibitor-968
reversesacquirederlotinibresistancebyblockingglutaminemetabolismin
non-smallcelllungcancer.Oncotarget(2016),7(1):610-21
8.WeihuaZhan,TianyuHan,ChenfuZhang,CaifengXie,MingxiGan,KeyuDeng,
MinguiFu*andJian-BinWang*.TRIM59inhibitstheproliferationand
migrationofnon-smallcelllungcancercellsbytargetingcellcyclerelated
proteins.PlosOne(2015),10(11):e0142596
9.Xiao-YuWang1+,Ming-XiGan1+,YongLi,Wei-HuaZhan,Tian-YuHan,
Xiao-JianHan,Jin-QuanChengandJian-BinWang*.Cdc42inducesEGF
receptorproteinaccumulationandpromotesEGFreceptornucleartransportand
cellulartransformation.FEBSLetters(2014),589（2）255-262.
10.LiXiangandJian-BinWang*.Maintenanceofchaperone-mediatedautophagy
activityinculturedcellsexpressingmutanthuntingtin.BiomedicalReports(2014),
2:529-532.
11.HanXJ,YangZJ,JiangLP,WangJBandWanYY.Mitochondrialdynamics
regulateshypoxia-inducedmigrationandantineoplasticactivityofcisplatinin
breastcancercells.InternationalJournalofOncology(2015),46(2):691-700.
12.TianyuHan+
,DeKang+
,DaokunJi+
,XiaoyuWang,WeihuaZhan，MinguiFu,
Hong-BoXinandJian-BinWang*.HowCancerCellMetabolismAffectsTumor
MigrationandInvasion.CellAdhesion&Migration(2013),7(5)：395-403.
13.WangJ.B.,Erickson,J.W.,Fuji,R.,Ramachandran,S.,Gao,P.,Dinavahi,R.,
Ambrosio,A.B.,Dias,S.M.,Wilson,K.,Dang,C.V.&Cerione,A.R.Targeting
mitochondrialglutaminaseactivityinhibitsoncogenictransformation.CancerCell
（2010),18:207-219（封面文章）IF:27.5
*国际肿瘤专家对此文章进行了专门评论（Preview）
Preview：LuW,PelicanoH,HuangP.Cancermetabolism:isglutaminesweeter
thanglucose?CancerCell.2010Sep14;18(3):199-200.
14.WangJ.B.,SonnR.,YemmsrachK.,SamorodnitskyT.andOsmanMA.
IQGAP1regulatescellproliferationthroughanovelCdc42-mTORpathway.
JournalofCellScience(2009),122，2024-33(Highlightededitoriallypaper).
15.Wang,J.B.,Wu,W.J.&Cerione,A.R.Cdc42andRascooperateto
mediatedcellulartransformationbyIntersectin-L.J.Biol.Chem(2005),280,
22883-22891.
16.Feng,Q.,Dan,B.,Wang,J.B.,Ly,T.,J.L.Guan&Cerione,A.R.Cool-1
functionsasanessentialregulatorynodeforEGFreceptor-andSrc-mediatedcell
growth.NatureCellBiology(2006),8,945-956.IF:19.6
17.LyT.K.,WangJ.B.,PereiraR.,RojasK.S.,PengX.,FengQ.,CerioneA.R&
WilsonK.F.ActivationoftheRanGTPaseissubjecttogrowthfactorregulation
andgiverisetocellulartransformation.J.Biol.Chem(2010),285,5815-26.
18.Fidyk,N.,Wang,J.B.&CerioneR.A*.Influencingcellular
transformationbymodulatingtheratesofGTPhydrolysisbyCdc42.
Biochemistry(2006),45,7750-7762.
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factor-dependentregulationofCdc42ismediatedbytheSrctyrosinekinase.J.
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Fulgoridae).ParasitologyResearch83,499-503(1997).
22.Cheung,W.W.K.&Wang,J.B.ElectronmicroscopicstudiesonNosema
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