个人简介
张国文，二级教授，博士，博士生导师，南昌大学食品学院副院长，江西省“百千万人才工程”人选，江西省高等学校中青年学科带头人，南昌大学食品科学与技术国家重点实验室固定成员与学术带头人，国家自然科学基金评审专家，国家重点研发项目评审专家，中国工程教育专业认证专家，FoodChemistry,JournalofAgriculturalandFoodChemistry,AnalyticalChemistry,JournalofHazardousMaterials,JournalofFunctionalFoods,FoodandFunction,FoodResearchInternational,食品科学等30多家国内外学术期刊特邀审稿专家。
讲授课程
承担的本科生课程：
食品分析、现代食品检测技术、膳食营养与健康、食品分析实验、现代食品检测技术实验、食品科学技术前沿、认识实习、生产实习、毕业实习
承担的研究生课程：
高等分析化学、食品科学技术研究进展、营养与食品科学技术研究进展
学术成就
主持国家自然科学基金、教育部高校博士点基金（博导类）、国家重点实验室项目、江西省重大科技项目、江西省自然科学基金、江西省科技支撑项目等国家级和省部级科研项目20多项。在JournalofAgriculturalandFoodChemistry,FoodChemistry等国内外学术期刊上发表论文260多篇，其中SCI收录100多篇，入选ESI高被引论文8篇，ESI热点论文2篇，h指数31，WebofScience收录论文总被引频次3000多次，单篇最高被引200多次。获得国家级教学成果二等奖3项，江西省教学成果一等奖2项、二等奖3项，江西省自然科学三等奖2项，江西省高等学校科技成果三等奖1项和吉安市科技进步三等奖1项，主编教材4部。
近年来，指导的研究生已有16人获得研究生国家奖学金，6人获得江西省优秀硕士学位论文，多次被评为江西省优秀硕士学位论文指导教师和南昌大学优秀研究生指导教师，获得南昌大学“科研先进个人”、“中兴发展奖教金”、“江铃奖教金”和“教书育人”先进个人等荣誉。
承担课题
近年来承担的部分科研项目：
(1)基于化学计量学的合成食品添加剂体外DNA靶向作用检测技术及其作用机制研究(31460422).国家基金项目,2015.1-2018.12,主持.
(2)具有潜在致癌性的有机氮农药与DNA的相互作用机制(21167013).国家基金项目,2012.1-2015.12,主持.
(3)几种抗心血管病黄酮化合物与蛋白质的相互作用及典型食物营养物的影响机制(31060210),国家基金项目,2011.1-2013.12,主持.
(4)桦木酸对α-葡萄糖苷酶活性和糖基化终末产物形成的抑制作用及机理研究(SKLF-ZZB-201707),国家重点实验室项目,2017.1-2018.12,主持.
(5)高良姜素对α-葡萄糖苷酶活性及糖基化终末产物形成的抑制作用研究(20171BAB204029),江西省基金项目,2017.1-2018.12,主持.
(6)几种具有潜在致癌性的人工合成食品添加剂与靶分子DNA的识别机制(20123601110005).教育部高等学校博士学科点基金项目（博导类）,2013.1-2015.12,主持.
(7)食品中化学危害因子风险的形成机制及检测新技术研究(20143ACB20006).江西省重大科技项目,2015.1-2017.12,主持.
(8)山柰酚、桑色素抑制黄嘌呤氧化酶活性的分子机制及其联合抑制行为研究(20142BAB204001).江西省基金项目,2014,1-2015.12,主持.
(9)蛋白质-多糖对芹菜素的包载、释放及其抑制α-葡萄糖苷酶活性的机制研究(GJJ150187).江西省教育厅科技项目,2016.1-2018.12,主持.
(10)基于化学计量学的合成食品添加剂DNA靶向作用检测新技术研究(20141BBG70092).江西省科技支撑项目,2014,1-2015.12,主持.
(11)棕榈油在胶囊中作为营养物载体的应用，大马棕榈油技术研发（上海）有限公司（横向课题）,2018.1-2019.12.主持.
(12)棕榈油在在野生菌油中的应用，大马棕榈油技术研发（上海）有限公司（横向课题）,2019.1-2020.12.主持.
近期论文
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(1)LiZeng#,HuafangDing#,XingHu,GuowenZhang*,DemingGong.Galangininhibitsα-glucosidaseactivityandformationofnon-enzymaticglycationproducts.FoodChemistry,2019,271:70-79.
(2)RuiWang,XingHu,JunhuiPan,DemingGong,GuowenZhang*.Interactionbetweenquinolineyellowandhumanserumalbumin:Spectroscopic,chemometricsandmoleculardockingstudies.JournaloftheScienceofFoodandAgriculture,2019,99(1):73-82.
(3)XingHu,JiaweiDu,JunhuiPan,FengfengWang,DemingGong,GuowenZhang*.Colorimetricdetectionoftheβ-agonistractopamineinanimalfeed,tissueandurinesamplesusinggold–silveralloynanoparticlesmodifiedwithsulfanilicacid.FoodAdditives&Contaminants:PartA,2019,36(1):35-45.
(4)RuiWang,YingyingLiu,XingHu,JunhuiPan,DemingGong,GuowenZhang*.Newinsightsintothebindingmechanismbetweenostholeandβ-lactoglobulin:Spectroscopic,chemometricsanddockingstudies.FoodResearchInternational,2019,120:226-234.
(5)MeihuiFan#,HuafangDing#,GuowenZhang*,XingHu,DemingGong.Relationshipsofdietaryflavonoidstructurewithitstyrosinaseinhibitoryactivityandaffinity.LWT-FoodScienceandTechnology,2019,107:25-34.
(6)HuafangDing,XingHu,XimingXu,GuowenZhang*,DemingGong.Inhibitorymechanismoftwoallostericinhibitors,oleanolicacidandursolicacidonα-glucosidase.InternationalJournalofBiologicalMacromolecules,2018,107:1844-1855.
(7)CenZhang,RuiWang,GuowenZhang*,DemingGong.Mechanisticinsightsintotheinhibitionofquercetinonxanthineoxidase.InternationalJournalofBiologicalMacromolecules,2018,112:405-412.
(8)HuafangDing,XiaqingWu,JunhuiPan,XingHu,DemingGong,GuowenZhang*.Newinsightsintotheinhibitionmechanismofbetulinicacidonα-glucosidase.JournalofAgriculturalandFoodChemistry,2018,66,7065-7075.
(9)XiaqingWu,HuafangDing,XingHu*,JunhuiPan,YijingLiao,DemingGong,GuowenZhang*.Exploringinhibitorymechanismofgallocatechingallateona-amylaseanda-glucosidaserelevanttopostprandialhyperglycemia.JournalofFunctionalFoods,2018,48:200-209.
(10)NiZeng,GuowenZhang*XingHu,JunhuiPan,ZhishengZhou,DemingGong.Inhibitionmechanismofbaicaleinandbaicalinonxanthineoxidaseandtheirsynergisticeffectwithallopurinol.JournalofFunctionalFoods,2018,50:172-182.
(11)JiaweiDu,XingHu,GuowenZhang*,XiaqingWu,andDemingGong.ColorimetricdetectionofcadmiuminwaterusingL-cysteine-functionalizedgold–silvernanoparticles.AnalyticalLetters,2018,51(18):2906-2919.
(12)CenZhang,GuowenZhang*,YijingLiao,DemingGong.Myricetininhibitsthegenerationofsuperoxideanionbyreducedformofxanthineoxidase.FoodChemistry,2017,221:1569-1577.
(13)MeihuiFan,GuowenZhang*,JunhuiPan,DemingGong.AninhibitionmechanismofdihydromyricetinontyrosinaseandthejointeffectsofvitaminsB6,D3orE.Food&Function,2017,8(7):2601-2610.
(14)MeihuiFan,GuowenZhang*,XingHu,XimingXu,DemingGong.Quercetinasatyrosinaseinhibitor:Inhibitoryactivity,conformationalchangeandmechanism.FoodResearchInternational,2017,100:226-233.
(15)SongLi,JunhuiPan,GuowenZhang*,JianjianXu,DemingGong.Characterizationofthegroovebindingbetweendi-(2-ethylhexyl)phthalateandcalfthymusDNA.InternationalJournalofBiologicalMacromolecules,2017,101:736-746.
(16)KaixinXia,GuowenZhang*,DemingGong.DecipheringtheintercalativebindingmodesofbenzoylperoxidewithcalfthymusDNA.Luminescence:TheJournalofBiologicalandChemicalLuminescence,2017,32(6):988-998.
(17)KaixinXia,GuowenZhang*,SongLi,DemingGong.GroovebindingofvanillinandethylvanillintocalfthymusDNA.JournalofFluorescence,2017,27(5):1815-1827.
(18)YingyingLiu,GuowenZhang*,NiZeng,SongHu.Interactionbetween8-methoxypsoralenandtrypsin:Monitoringbyspectroscopic,chemometricsandmoleculardockingapproaches.SpectrochimicaActa,PartA,2017,173:188-195
(19)SuyunLin,LiZeng,GuowenZhang*,YijingLiao,DemingGong.Synthesis,characterizationandxanthineoxidaseinhibitionofCu(II)–chrysincomplex.SpectrochimicaActa,PartA,2017,178:71-78.
(20)XiPeng,GuowenZhang*,YijingLiao,DemingGong.Inhibitorykineticsandmechanismofkaempferolonα-glucosidase.FoodChemistry,2016,190(1):207-215.
(21)MoTao,GuowenZhang*,JunhuiPan,ChunhongXiong.Decipheringthegroovebindingmodesoftau-fluvalinateandflumethrinwithcalfthymusDNA.SpectrochimicaActa,PartA,2016,155(15):28-37.
(22)XiaoyueZhou,CenZhang,GuowenZhang*,YijingLiao.Intercalationofdaphnetin–Cu(II)complexwithcalfthymusDNA.RSCAdvances,2016,6:5408-5418.
(23)XiPeng,GuowenZhang*,LiZeng.Inhibitionofα-glucosidasebyvitaminD3andtheeffectofvitaminsB1andB2.Food&Function,2016,7(2):982-991.
(24)SuyunLin,GuowenZhang*,YijingLiao,DemingGong.InhibitorykineticsandmechanismofdietaryvitaminsD3andB2onxanthineoxidase.Food&Function,2016,7:2849-2861.
(25)LiZeng,GuowenZhang*,YijingLiao,DemingGong.Inhibitorymechanismofmorinonα-glucosidaseanditsanti-glycationproperties.Food&Function,2016,7:3953-3963.
(26)LiZeng,GuowenZhang*,SuyunLin,DemingGong.Inhibitorymechanismofapigeninonα-glucosidaseandsynergyanalysisofflavonoids.JournalofAgriculturalandFoodChemistry,2016,64(37):6939–6949.
(27)CenZhang,GuowenZhang*,JunhuiPan,DemingGong.Galangincompetitivelyinhibitsxanthineoxidasebyaping-pongmechanism.FoodResearchInternational,2016,89:152-160.
(28)YapingWang,GuowenZhang*,LanghongWang.Potentialtoxicityofphthalicacidestersplasticizer:Interactionofdimethylphthalatewithtrypsininvitro.JournalofAgriculturalandFoodChemistry,2015,63(1):75-84.
(29)YajieWang,GuowenZhang*,JunhuiPan,DemingGong.Novelinsightsintotheinhibitorymechanismofkaempferolonxanthineoxidase.JournalofAgriculturalandFoodChemistry,2015,63(2):526-534.
(30)YueZhang,JunhuiPan,GuowenZhang*,XiaoyueZhou.IntercalationofherbicidepropyzamideintoDNAusingacridineorangeasafluorescenceprobe.Sensors&Actuators:B.Chemical,2015,206:630-639.
(31)XiaoyueZhou,GuowenZhang*,JunhuiPan.Groovebindinginteractionbetweendaphnetinandcalfthymus.InternationalJournalofBiologicalMacromolecules,2015,74:185-194.
(32)SuyunLin,GuowenZhang*,YijingLiao,JunhuiPan,DemingGong.Dietaryflavonoidsasxanthineoxidaseinhibitors:Structure–affinityandstructure–activityrelationships.JournalofAgriculturalandFoodChemistry,2015,63(2):7784-7794.
(33)SuyunLin,GuowenZhang*,JunhuiPan,DemingGong.Decipheringtheinhibitorymechanismofgenisteinonxanthineoxidaseinvitro.JournalofPhotochemistryandPhotobiologyB:Biology,2015,153:463-472.
(34)LanghongWang,MoTao,GuowenZhang*,SongLi,DemingGong.PartialintercalativebindingoffoodcoloranterythrosinetoherringspermDNA.RSCAdvances,2015,5(119):98366-98376.
(35)YuLi,GuowenZhang*,JunhuiPan,YueZhang.DeterminationofmetolcarbbindingtoDNAbyspectroscopicandchemometricsmethodswiththeuseofacridineorangeasaprobe.Sensors&Actuators:B.Chemical,2014,191:464-472.
(36)JiakaiYan,GuowenZhang*,JunhuiPan,YajieWang.α-Glucosidaseinhibitionbyluteolin:Kinetics,interactionandmoleculardocking.InternationalJournalofBiologicalMacromolecules,2014,64:213-223.
(37)GuowenZhang*,LanghongWang,XiaoyueZhou,YuLi,DemingGong.BindingcharacteristicsofsodiumsaccharinwithcalfthymusDNAinvitro.JournalofAgriculturalandFoodChemistry,2014,62(4):991-1000.
(38)YajieWang,GuowenZhang*,JiakaiYan,DemingGong.Inhibitoryeffectofmorinontyrosinase:Insightsfromspectroscopicandmoleculardockingstudies.FoodChemistry,2014,163:226-233.
(39)GuowenZhang*,YadiMa.Mechanisticandconformationalstudiesontheinteractionoffooddyeamaranthwithhumanserumalbuminbymultispectroscopicmethods.FoodChemistry,2013,136(2):442-449.
(40)YapingWang,GuowenZhang*,LanghongWang.Interactionofprometryntohumanserumalbumin:Insightsfromspectroscopicandmoleculardockingstudies.PesticideBiochemistryandPhysiology,2014,108:66–73.
(41)XiaoyueZhou,GuowenZhang*,LanghongWang.ProbingthebindingmodeofpsoralentocalfthymusDNA.InternationalJournalofBiologicalMacromolecules,2014,67:228-237.
(42)GuowenZhang*,YutingHu,JunhuiPan.Interactionbetweentoddalolatoneandhumanserumalbumin.JournalofSolutionChemistry,2014,43(4):727-745.
(43)XiaoyueZhou,GuowenZhang*,LanghongWang.Bindingof8-methoxypsoralentoDNAinvitro:MonitoringbySpectroscopicandchemometricsapproaches.JournalofLuminescence,2014,154:116-123.
(44)YuLi,GuowenZhang*,MoTao.BindingpropertiesofherbicidechlorprophamtoDNA:Spectroscopic,chemometricsandmodelinginvestigations.JournalofPhotochemistry&Photobiology,B:Biology,2014,138:109-117.
(45)LanghongWang,GuowenZhang*,JunhuiPan,ChunhongXiong,DemingGong.IntercalationbindingoffoodantioxidantbutylatedhydroxyanisoletocalfthymusDNA.JournalofPhotochemistry&Photobiology,B:Biology,2014,141:253-261.
(46)YueZhang,GuowenZhang*,YuLi,YutingHu.ProbingthebindingofinsecticidepermethrintocalfthymusDNAbyspectroscopictechniquesmergingwithchemometricsmethod.JournalofAgriculturalandFoodChemistry,2013,61(11):2638-2647.
(47)GuowenZhang*,PengFu,JunhuiPan.MultispectroscopicstudiesofpaeoniflorinbindingtocalfthymusDNAinvitro.JournalofLuminescence,2013,134:303-309.
(48)GuowenZhang*,MingmingHu,LiHe,PengFu,LinWang,JiaZhou.Optimizationofmicrowave-assistedenzymaticextractionofpolyphenolsfromwastepeanutshellsandevaluationofitsantioxidantandantibacterialactivitiesinvitro.FoodandBioproductsProcessing,2013,91(2):157-167.
(49)GuowenZhang*,YepengZhang,YueZhang,YuLi.SpectroscopicstudiesofcyanazinebindingtocalfthymusDNAwiththeuseofethidiumbromideasaprobe.Sensors&Actuators:B.Chemical,2013,182:453-460.
(50)GuowenZhang*,YadiMa.Spectroscopicstudiesontheinteractionofsodiumbenzoate,afoodpreservative,withcalfthymusDNA.FoodChemistry,2013,141(1):41-47.
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