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基因治疗与基因药物输送

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Qian Ding, Xiaofei Si, Dan Liu, Jinliang Peng, Hailing Tang, Wenqiang Sun, Mengjie Rui, Qunli Chen, Lieyi Wu, Yuhong Xu.Targeting and liposomal drug delivery to CD40L expressing T cells for treatment of autoimmune diseases. J Control Release. 2015,207:86-92. Shuang Hou, Jin-sil Choi, Kuan-Ju Chen, Yang Zhang, Jinliang Peng, Mitch A. Garcia, Jue-Hua Yu, Kaushali Thakore-Shah, Tracy Ro, Jie-Fu Chen, Parham Peyda, Guoping Fan, April D. Pyle, Hao Wang, Hsian-Rong Tseng. Supramolecular nanosubstrate mediated delivery for reprogramming and transdifferentiation of Mammalian cells. Small. 2015 ,11(21):2499-504. Yanzhu Yang, Qian Ding, Jian Chen, Jinliang Peng*, Yuhong Xu*. Multi-walled Carbon Nanotube Modified PLGA Scaffolds for Dendritic Cell Culture. J Biomed Mater Res A. 2015, 103(3):1045-52. Hailing Tang, Xiaojing Chen, Mengjie Rui, Wenqiang Sun, Jian Chen, Jinliang Peng, Yuhong Xu. Effects of surface displayed targeting ligand GE11 on liposome distribution and extravasation in tumor. Mol Pharm. 2014,11(10): 3242-50. Jinliang Peng*, Sanyuan Shi, Zhen Yang, Qian Ding, Wangxi Hai, Hailing Tang, Yanzhu Yang, James R. Bernstein, Parham Peyda, Yuhong Xu. Short-fragment DNA improves the immune response of electroporation-mediated DNA vaccination. Gene Therapy. 2014,21(7):703-708 Jinliang Peng, Mitch André Garcia, Libo Zhao, Kuan-Ju Chen, James R. Bernstein, Yu-Sheng Hsiao, Katherine W. Liu, Wei-Yu Lin, Hao Wang, Shuang Hou, Hsian-Rong Tseng. Nanosubstrate-mediated delivery of genes that are encapsulated in self-assembled nanoparticles. ACS Nano. 2014,8 (5):4621–29 Jinliang Peng*, Yonggang Zhao, Yuhong Xu. Short-fragment DNA-mediated in vivo DNA electroporation delivery. Methods Mol Biol. 2014;1121:61-7. Maoquan Chu, Yuxiang Shao, Jinliang Peng, Xiangyun Dai, Haikuo Li, Qingsheng Wu, Donglu Shi. Near-infrared laser light mediated cancer therapy by photothermal effect of Fe3O4 magnetic nanoparticles. Biomaterials. 2013;34(16): 4078-88. Maoquan Chu, Jinliang Peng, Jiajia Zhao, Shanlu Liang, Yuxiang Shao, Qiang Wu. Laser light triggered-activated carbon nanosystem for cancer therapy. Biomaterials. 2013; 34(7):1820-32. Jing Bai, Zhengyuan Zhou, Hailing Tang, Shuxian Song, Jinliang Peng, Yuhong Xu. Impact of PEGylation on biodistribution and tumor accumulation of Lipid-Mu peptide-DNA. J Liposome Res. 2013; 23(1):1-10. Jinliang Peng*, Yonggang Zhao, Junhua Mai, Wei Guo, Yuhong Xu. Short noncoding DNA fragment improve efficiencies of in vivo electroporation-mediated gene transfer. J Gene Med. 2012; 14(9-10):563-9. Maoquan Chu, Xiaojing Pan, Ding Zhang, Qiang Wu, Jinliang Peng, Waixi Hai. The therapeutic efficacy of CdTe and CdSe quantum dots for photothermal cancer therapy. Biomaterials. 2012; 33(29):7071-83. Shuxian Song, Dan Liu, Jinliang Peng, Hongwei Deng, Yan Guo, Ming Yao, Zhonghai Li, Andrew D. Miller, Lisa Xu,Yuhong Xu. Peptide ligand directed liposome drug delivery toward EGFR high-expressing cancer cells in vitro and in vivo. FASEB J. 2009,23:1396-404 Junhua Mai, Shuxian Song, Mengjie Rui, Dan Liu, Qian Ding, Jinliang Peng, Yuhong Xu. A synthetic peptide mediated active targeting of cisplatin liposomes to Tie2 expressing cells. J. Control Release. 2009, 139(3): 174-81 Shuxian Song, Dan Liu, Jinliang Peng, Ye Sun, Zonghai Li, Jian-Ren Gu and Yuhong Xu. Peptide ligand-mediated liposome distribution and targeting to EGFR expressing tumor in vivo. Int J Pharm. 2008, 363(1-2):155-61 Jinliang Peng, Yonggang Zhao, Wengka Pang, Junhua Mai, Wei Guo, Guangming Cheng, Guoyu Mo, Guirong Rao, Yuhong Xu. Non cytolytic antigen clearance in DNA vaccinated mice with electroporation. Acta Pharmacologica Sinica. 2007,28(7):1024-30 Huifeng Qian, Chaoqing Dong, Jinliang Peng, Xin Qiu, Yuhong Xu, and Jicun Ren. High-quality and water-soluble near-infrared photoluminescent CdHgTe/CdS quantum dots prepared by adjusting size and composition. J. Phys. Chem. C. 2007, 111 (45), 16852 -7 Yong-Gang Zhao, Huili Lu, Jinliang Peng, Long Xu, Yufeng Li, Yuhong Xu. The Inhibition Effect of Ca2+ on in vivo Gene Transfer by Electroporation. Acta Pharmacologica Sinica. 2006,27(3):307-10 Yonggang Zhao, Baowei Peng, Hongwei Deng, Guangming Chen, Fuqiang Yang, Ming Shao, Huili Lu, Yufeng Li, Jinliang Peng, Long Xu, Yuhong Xu. Anti-HBV immune responses in rhesus macaques elicited by electroporation mediated DNA vaccination. Vaccine. 2006,24(7):897-903. Jinliang Peng, Yonggang Zhao, Junhua Mai, Yongjia Peng, Xiaohui Wei, Peizuo Zhang, Yuhong Xu. Inhibition of hepatitis B virus replication by various RNAi constructs and their pharmacodynamic properties. J Gen Virol. 2005;86: 3227-34.

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