研究领域
成体干细胞扩增机理及生物反应器3D定向分化的转化医学研究,动物细胞和工程微组织的反应器规模培养及应用;温敏性生物材料在动物细胞规模培养中的应用研究
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Sang Y, Zang W, Yan Y, Liu Y, Fu Q, Wang K, Chen Y*, Qi N. Study of differential effects of TGF-beta3/BMP2 on chondrogenesis in MSC cells by gene microarray data analysis. Mol Cell Biochem. 2014 Jan;385(1-2):191-8.
Li, Weiwei; Li, Min; Chen, Yantian; et al. Various seeding methods for tissue development of human umbilical-cord-derived mesenchymal stem cells in 3-dimensional PET matrix BIOTECHNOLOGY AND BIOPROCESS ENGINEERING 2014 Volume: 19 Issue: 1 Pages: 108-117
Sang Y, Xie K, Mu Y, Lei Y, Zhang B, Xiong S, Chen Y, Qi N. Salt ions and related parameters affect PEI-DNA particle size and transfection efficiency in Chinese hamster ovary cells. Cytotechnology. 2013 Oct 29. [Epub ahead of print]
Li Wei-wei; Liu Shao-jiao; Chen Yan-tian; et al. Effects of the dilution rate on cell cycle distribution and PEI-mediated transient gene expression by CHO cells in continuous culture. PROCESS BIOCHEMISTRY 2013 Volume: 48 Issue: 10 Pages: 1572-1580
Chen Y, Bloemen V, Impens S, Moesen M, Luyten FP, Schrooten J. Characterization and Optimization of Cell Seeding in Scaffolds by Factorial Design: Quality by Design Approach for Skeletal Tissue Engineering.Tissue Eng Part C Methods. 2011 Dec;17(12):1211-21 (SCI IF=
Chen Y, Maarten Sonnaert, Scott J. Roberts , Frank Luyten, Jan Schrooten, Validation of a PicoGreen based DNA quantification integrated in an RNA extraction method for 2D and 3D cell cultures. Tissue Engineering Part C: Methods. doi:10.1089/ten.tec.2011.0304.
Impens S, Chen Y, Mullens S, Luyten F, Schrooten J. Controlled cell-seeding methodologies: a first step toward clinically relevant bone tissue engineering strategies. Tissue Eng Part C Methods.2010 Dec;16(6):1575-83.
Roberts SJ, Chen Y, Moesen M, Schrooten J, Luyten FP. Enhancement of osteogenic gene expression for the differentiation of human periosteal derived cells. Stem Cell Res. 2011 Sep;7(2):137-44.
Chai, Y., Roberts, S., Van Bael, S, Chen, Y., Luyten, F. Schrooten, J., Multi-Level Factorial Analysis of Ca2+/Pi Supplementation as Bio-Instructive Media for In Vitro Biomimetic Engineering of 3D Osteogenic Hybrids. Tissue Eng Part C Methods. 2012 Feb;18(2):90-103
张淑香,陈彦田*,齐念民.人脐带间充质干细胞半连续灌注培养的工艺优化:I 灌注启动时间、灌注频率和灌注体积. 中国组织工程研究与临床康复,中国组织工程研究 第17 卷 第6 期,1005-1011
张淑香,陈彦田*,齐念民.葡萄糖和谷氨酰胺浓度对人脐带间充质干细胞体外培养的影响. 组织工程与重建外科杂志,2012年8 月第8 卷第4 期185-188
Jihong Yan, Liu Yang, Guirong Wang, Yang Xiao, Baohong Zhang and Nianmin Qi, Biocompatibility evaluation of chitosan-based injectable hydrogels for the culturing mice mesenchymal stem cells in vitro. J Biomater Appl 2010 24: 625
Tao Geng, Haiying Sun, Fengshan Luo, Nianmin Qi, Quantitative analysis of the responses of murine bone marrow mesenchymal stem cells to EGF, PDGF-BB and fibronectin by factorial design methodology. Cytotechnology (2008) 58:93–101
Huang L, Dong L, Chen Y, Qi H, Xiao D. Effects of sinusoidal magnetic field observed on cell proliferation, ion concentration, and osmolarity in two human cancer cell lines. Electromagn Biol Med. 2006;25(2):113-26.
Lingzhen Huang, Liang Dong, Yantian Chen, Hanshi Qi, and Dengming Xiao, Effects of sinusoidal 50 Hz magnetic field on viability, cell cycle and apoptosis of HL-60 cells, Eur. Phys. J. Appl. Phys. 35, 217–221 (2006)