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个人简介

2019.06– 浙大化学系, 百人计划研究员,博导,国家海外高层次人才引进计划 2018.11–2019.06 日本理化所,JSPS博士后,合作教授:Prof. Zhaomin Hou 2014.09–2018.11 德国明斯特大学,洪堡学者博士后,合作教授:Prof. Frank Glorius 2009.09–2014.07 四川大学化学学院,有机化学博士,导师:冯小明院士 2005.09–2009.07 四川大学化学学院,理学学士,导师:冯小明院士

研究领域

1. 不对称催化:新型配体和催化剂的设计开发,新型不对称催化反应的研究,以及手性药物和天然产物的高效合成及相关药物化学研究。 2. 导向药物,天然产物和材料的有机合成方法学 3. 高分子合成和新材料

近期论文

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Wei Li,* Tobias Wagener, Lars Hellmann, Constantin G. Daniliuc, Christian Mück-Lichtenfeld, Johannes Neugebauer,* and Frank Glorius* 'Design of Ru(II)-NHC-Diamine Precatalysts Directed by Ligand Cooperation: Applications and Mechanistic Investigations for Asymmetric Hydrogenation' J. Am. Chem. Soc. 2020, ASAP, DOI: 10.1021/jacs.0c00985. Wei Li, M. Wollenburg, Frank Glorius* 'Enantioselective synthesis of 2-oxazolidinones by ruthenium(II)–NHC-catalysed asymmetric hydrogenation of 2-oxazolones' Chem. Sci. 2018, 9, 6260. Mario P. Wiesenfeldt, Zackaria Nairoukh, Wei Li, Frank Glorius* “Hydrogenation of fluoroarenes: Direct access to all-cis-(multi)fluorinated cycloalkanes” Science 2017, 357, 908–912. Wei Li, Mario P. Wiesenfeldt, and Frank Glorius* “Ruthenium-NHC-Diamine Catalyzed Enantioselective Hydrogenation of Isocoumarins”J. Am. Chem. Soc. 2017, 139, 2585–2588. (highlighted by Synfacts 2017, 13, 494) Wei Li, Christoph Schlepphorst, Constantin Daniliuc, and  Frank Glorius* “Asymmetric Hydrogenation of Vinylthioethers: Access to Optically Active 1,5-Benzothiazepine Derivatives” Angew. Chem. Int. Ed. 2016, 55, 3300–3303. (highlighted by Synfacts 2016, 12, 443) Wei Li, Fei Tan, Xiaoyu Hao, Gang Wang, Yu Tang, Xiaohua Liu, Lili Lin and Xiaoming Feng* “Catalytic Asymmetric Intramolecular Homologation of Ketones with α-Diazoesters: Synthesis of Cyclic α-Aryl/Alkyl β-Ketoesters” Angew. Chem. Int. Ed. 2015, 54, 1608–1611. (highlighted by Synfacts 2015, 11, 0278; Chin. J. Org. Chem. 2015, 35, 739) Wei Li, Xiaohua Liu, Fei Tan, Xiaoyu Hao, Jianfeng Zheng, Lili Lin, and Xiaoming Feng* “Catalytic Asymmetric Homologation of α-Ketoesters with α-Diazoesters: Synthesis of Succinate Derivatives with Chiral Quaternary Centers”Angew. Chem. Int. Ed. 2013, 52, 10883–10886. (highlighted by Synfacts 2014, 10, 55) Wei Li, Xiaohua Liu, Xiaoyu Hao, Yunfei Cai, Lili Lin, and Xiaoming Feng* “A Catalytic Asymmetric Ring-Expansion Reaction of Isatins and α-Alkyl-α-Diazoesters: Highly Efficient Synthesis of Functionalized 2-Quinolone Derivatives” Angew. Chem. Int. Ed. 2012, 51, 8644–8647. (highlighted by Synfacts 2012, 8, 1236) Wei Li, Xiaohua Liu, Xiaoyu Hao, Xiaolei Hu, Yangyang Chu, Weidi Cao, Song Qin, Changwei Hu, Lili Lin, and Xiaoming Feng* “New Electrophilic Addition of α-Diazoesters with Ketones for Enantioselective C-N Bond Formation” J. Am. Chem. Soc. 2011, 133, 15268–15271. (highlighted by Synfacts 2012, 8, 63) Wei Li, Jun Wang, Xiaolei Hu, Ke Shen, Wentao Wang, Yangyang Chu, Lili Lin, Xiaohua Liu, and Xiaoming Feng* “Catalytic Asymmetric Roskamp Reaction of α-Alkyl-α-diazoesters with Aromatic Aldehydes: Highly Enantioselective Synthesis of α-Alkyl-β-keto Esters” J. Am. Chem. Soc. 2010, 132, 8532–8533.

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