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个人简介

学习经历 2006/09 – 2009/07,哈尔滨医科大学,公共卫生学院,博士,导师:曲章义 2003/09 – 2006/07,黑龙江中医药大学,基础医学院,硕士,导师:王亚贤 1998/09 – 2003/07,黑龙江中医药大学,临床医学院中医系,学士 工作经历 2013/07 – 至今,暨南大学,生命科学技术学院,副研究员 2012/04 – 2013/06,北京泰诺迪生物科技有限公司,项目经理 2009/09 – 2012/04,中国医学科学院/北京协和医学院,病原生物学研究所,博士后,导师:何有文/金奇

研究领域

主要从事天然全人源单克隆抗体的分离鉴定及抗体生物信息学等研究与教学工作

近期论文

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Assessing the performance of the g_mmpbsa tools to simulate the inhibition of oseltamivir to influenza virus neuraminidase by molecular mechanics Poisson–Boltzmann surface area methods. J Chin Chem Soc. 2019;1–8. Molecular Docking and Molecular Dynamics (MD) Simulation of Human Anti-Complement Factor H (CFH) Antibody Ab42 and CFH Polypeptide. Int. J. Mol. Sci. 2019, 20, 2568. Effect of ForceFields and Water Models of EGFRvIII (scFv) Complex by Molecular Dynamics Simulation, MM-PBSA Calculation, and ITC Experiment, Chem J Chinese Universities, 2017,11(38), 2070-2076. Molecular interactions of GABA analogues against the α+β-interface of GABAA receptor: docking and molecular dynamics studies. Digest Journal of Nanomaterials and Biostructures. 2015, 10(3): 811-822. Antithrombotic Effect of Ligustrazine Hydrochloride Injection on the model of induced arteriovenous shunt thrombosis.J Res Med Sci. 2013, 18(8): 704-706. Iridoid glycosides extracted from Zhizi(FructusGardeniae ) decrease collagen-induced platelet aggregation and reduce carotid artery thrombosis in an invivo rat model. J Tradit Chin Med. 2013, 33(4):531-534. Susceptibility of Commercial Neuraminidase Inhibitors Against 2013 A/H7N9 Influenza Virus: A Docking and Molecular Dynamics Study. Journal of Theoretical and Computational Chemistry.Vol. 12, No. 8,1350069 (2013) . A Novel Antibody Humanization Method Based on Epitopes Scanning and Molecular Dynamics Simulation. PLoS ONE, 2013, 8(11): e80636. Phylogenetic and Structural Analysis of Major Surface Proteins Hemagglutinin (HA) and Neuraminidase (NA) of Novel Avian Influenza Virus A H7N9 From Chinese Patient, Chem Res Chinese Universities, 2013, 29(5): 934-940. Structure based High throughput Epitope Analysis of Hexon Proteins in B and C species of Human Adenoviruses (HAdVs). PLoS One. 2012, 7(3): e32938. Novel Rapid Molecular Modeling Method Based on Evolutional Tree for Human Adenovirus Hexon Proteins Family.Chem. J. Chinese Universities, 2011; 32:1838-1844. Homology Modeling and Evolution Trace Analysis of Human Adenovirus Type 3 Hexon. Chem J Chinese Universities,2009; 30:1636-1640. Molecular modeling and epitopes mapping of human adenovirus type 3 hexonprotein.Vaccine, 2009; 27:5103–5110."

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