个人简介
学习经历
1995: PhD, University of Sheffield, UK
1988: MSc, JinanUniversity/Sun Yat-Sen University, China
1985: BSc, Jinan University, China
工作经历
2005 – Present: Professor and Director, Jinan University, China
2002 – 2006: Assistant Professor (Research), University of Hong Kong, Hong Kong
1996 – 2002: Post Doc. - Research Associate - Research Assistant Professor, University of Vermont, USA
1991 – 1992: Visiting Scholar, University of Oxford, UK
近期论文
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1.Lu S, Zhang J, Lian X, Sun L, Meng K, Chen Y, Sun Z, Yin X, Li Y, Zhao J, Wang T, Zhang G, He QY. A hidden human proteome encoded by 'non-coding' genes. Nucleic Acids Res. 2019 Jul 24. doi: 10.1093/nar/gkz646. (IF = 11.147)
2.Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, Zhou Q, Zeng G, Hu X, Yu L, Zhou S, Tong X, Huang H, Chen H, Liu Q, Liu W, Zhang G, Zeng M, Zhou G, He QY, Ji H, Chen L. “Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition.”Nat Commun. 2019 Apr 10;10(1):1665. doi: 10.1038/s41467-019-09295-7. (IF = 11.878)
3.Yang J, Xu WW, Hong P, Ye F, Huang XH, Hu HF, Zhang QH, Yan X, Li B, He QY. Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction. Cancer Lett. 2019 Mar 11;451:79-91. doi: 10.1016/j.canlet.2019.02.050. (IF = 6.508)
4.Yang J, Li B,He QY. “Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment.” Cell Death Dis. doi: 10.1038/s41419-018-0661-3. (IF = 5.965)
5.Gao J, Wang Y, Yang J, Zhang W, Meng K, Sun Y, Li Y, He QY. “RNF128 Promotes Invasion and Metastasis Via the EGFR/MAPK/MMP-2 Pathway in Esophageal Squamous Cell Carcinoma.” Cancers (Basel). 2019 Jun 18;11(6). doi: 10.3390/cancers11060840. (IF = 6.162)
6.Liu WT, Wang Y, Zhang J, Ye F, Huang XH, Li B, He QY. “A novel strategy of integrated microarray analysis identifies CENPA, CDK1 and CDC20 as a cluster of diagnostic biomarkers in lung adenocarcinoma.” Cancer Lett. doi:10.1016/j.canlet.2018.03.043. (IF = 6.508)
7.Xu WW, Li B, Zhao JF, Yang JG, Li JQ, Tsao SW, He QY, Cheung ALM. “IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness.” Cancer Lett.doi: 10.1016/j.canlet.2018.03.039. (IF = 6.508)
8.Zhong Y, Yang J, Xu WW, Wang Y, Zheng CC, Li B, He QY. “KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition.” Oncogene. doi: 10.1038/onc.2017.287. (IF = 6.634)
9.Zhang J, Lu SH, Zhou Y, Meng K, Chen ZP, Cui YZ, Shi YF, Wang T, He QY. “Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.” Proteomics. doi: 10.1002/pmic.201700103. (IF = 3.106)
10.Wang Y, Zhang J, Huang ZH, Huang XH, Zheng WB, Yin XF, Li YL, Li B, He QY. “Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop.” Cell Death Dis. doi: 10.1038/cddis.2017.265. (IF = 5.959)
11.Li B, Xu WW, Han L, Chan KT, Tsao SW, Lee NP, Law S, Xu LY, Li EM, Chan KW, Qin YR, Guan XY, He QY, Cheung AL. “MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF.” Oncogene. doi: 10.1038/onc.2017.29. ( IF = 6.634)
12.Xu WW, Li B, Guan XY, Chung SK, Wang Y, Yip YL, Law SY, Chan KT, Lee NP, Chan KW, Xu LY, Li EM, Tsao SW, He QY, Cheung AL. “Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression.” Nat Commun. doi: 10.1038/ncomms14399. (IF = 11.878)
13.Li B, Xu WW, Guan XY, Qin YR, Law S, Lee NP, Chan KT, Tam PY, Li YY, Chan KW, Yuen HF, Tsao SW, He QY, Cheung AL. “Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance.” Clin Cancer Res. doi: 10.1158/1078-0432.CCR-15-1196. (IF = 8.911)
14.Lian XL, Guo JH, Gu W, Cui YZ, Zhong JY, Jin JJ, He QY, Wang T, Zhang G. “Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells.” PLoS Genet. doi: 10.1371/journal.pgen.1005901. (IF = 5.224)
15.Yang XY, He K, Du GF, Wu XH, Yu GC, Pan YL, Zhang G, Sun XS, He QY. “Integrated Translatomics with Proteomics to Identify Novel Iron-Transporting Proteins in Streptococcus pneumoniae.” Front Microbiol. doi: 10.3389/fmicb.2016.00078. (IF = 4.259)
16.Zhong J, Xiao C, Gu W, Du G, Sun X, He QY, Zhang G. “Transfer RNAs Mediate the Rapid Adaptation of Escherichia coli to Oxidative Stress.” PLoS Genet. doi: 10.1371/journal.pgen.1005302. (IF = 5.224)
17.Yu G, Wang LG, He QY. “ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization.” Bioinformatics. doi: 10.1093/bioinformatics/btv145. (IF = 4.531)
18.Yu G, Wang LG, Yan GR, He QY. “DOSE: an R/Bioconductor package for disease ontology semantic and enrichment analysis.” Bioinformatics. doi: 10.1093/bioinformatics/btu684. (IF = 4.531)
19.Li B, Tsao SW, Chan KW, Ludwig DL, Novosyadlyy R, Li YY, He QY, Cheung AL. “Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy.” Clin Cancer Res. doi:10.1158/1078-0432.CCR-13-2735. (IF = 8.911)
20.Wang T, Cui Y, Jin J, Guo J, Wang G, Yin X, He QY, Zhang G. “Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific.” Nucleic Acids Res. 2013 May;41(9):4743-54. doi: 10.1093/nar/gkt178. (IF = 11.147)