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个人简介

教育经历 1996.9–2000.7 大连理工大学化工学院 学士 2000.9–2005.7 中国科学院长春应用化学研究所, 分析化学, 博士 2005.8-2008.1 以色利耶路撒冷希伯莱大学, 博士后 工作经历 2008.03-2018.1 中国科学院上海应用物理研究所, 物理生物学研究室, 研究员 2018.2 至今 华东师范大学化学与分子工程学院,教授 荣誉及奖励 国家自然科学基金委“杰出青年科学基金”(2022) 国家自然科学基金委“优秀青年科学基金”(2012) 上海市科委“青年科技启明星计划”及跟踪资助(2010,2013) 中国科学院青年创新促进会员 (2013),优秀会员(2017)

研究领域

单分子催化 单颗粒成像及催化 DNA纳米技术

近期论文

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Xiaoqing Chen, Qianyun Yang, Wenyan Kong, Yifan Ge,*, Jie He, An Yan, Di Li*, High Spatial-resolved Heat Manipulating Membrane Heterogeneity Alters Cellular Migration and Signaling, PNAS, 2023, 120, e2312603120 Hui Wang, Cuilin Zhu, Di Li*, Visualizing Enzyme Catalytic Process using Single-Molecule Techniques, TrAC-Trend. Anal. Chem. 2023, 117083 An Yan, Xiaoqing Chen, Jie He, Yifan Ge, Qing Liu, Dong Men, Ke Xu, Di Li*, Phosphorothioated DNA Engineered Liposomes as a General Platform for Stimuli-Responsive Cell-Specific Intracellular Delivery and Genome-Editing, Angew. Chem. Int. Ed. 2023, e202303973 (VIP) Jun-gang Wang, Linjuan Zhang, Jing Xie, Yossi Weizmann, Di Li*, Jinghong Li, Single Particle Hopping as an Indicator for Evaluating Electrocatalysts, Nano Lett. 2022, 22, 5495-5502 Yingying Su, Xiaoqing Chen, Hui Wang, Lele Sun, Ying Xu, Di Li*, Enhancing Cell Membrane Phase Separation for Inhibiting Cancer Metastasis with a Stimuli-responsive DNA Nanodevice, Chem. Sci. 2022, 13, 6303-6308 Xia Xiao, Kun Wu, An Yan, Jun-Gang Wang, Zhanxia Zhang, Di Li*, Intelligent Probabilistic System for Digital Tracing Cellular Origin of Individual Clinical Extracellular Vesicles, Anal. Chem. 2021, 93, 10343-10350 Jun-Gang Wang, Lifang Shi, Yingying Su, Liwei Liu, Zhenzhong Yang, Rong Huang, Jing Xie, Yang Tian, Di Li*, In-Situ Plasmonic Tracking Oxygen Evolution Reveals Multistage Oxygen Diffusion and Accumulating Inhibition, Nature Commun. 2021, 2164 (Editor's Choice) Wei Li, Junjian Miao, Tianhuan Peng, Hui Lv, Jun-Gang Wang, Kun Li, Ying Zhu, Di Li*, Single Molecular Catalysis Identifying Activation Energy of Intermediate Product and Rate limiting Step in Plasmonic Photocatalysis, Nano Lett. 2020, 20, 2507-2513 Lele Sun, Yingying Su, Jun-gang Wang, Fei Xia, Ying Xu, Di Li*, DNA Nanotweezers for Stabilizing and Dynamic Lighting up Lipid Raft on Living Cell membrane and Activation of T Cells, Chem. Sci. 2020, 11, 1581-1586 Yanjing Gao, Xiaoguo Liu, Lele Sun, Yan Xu, Sichun Yang, Chunhai Fan, Di Li*, Alleviated Inhibition of Single Enzyme in Confined and Crowded Environment, J. Phys. Chem. Lett. 2019, 10, 82-89 Lele Sun, Yanjing Gao, Yaoguang Wang, Qin Wei, Jiye Shi, Nan Chen, Di Li*, Chunhai Fan, Guiding Protein Delivery into Live Cells using DNA-Programmed Membrane Fusion, Chem. Sci. 2018, 9, 5967-5975 Yan Xu, Yanjing Gao, Yingying Su, Lele Sun, Feifei Xing, Chunhai Fan, Di Li*, Single Molecule Studies of Allosteric Inhibition of Individual Enzyme on a DNA Origami Reactor, J. Phys. Chem. Lett. 2018, 9, 6786-6794 Tianhuan Peng, Junjian Miao, Zhaoshuai Gao, Linjuan Zhang*, Yi Gao, Chunhai Fan, Di Li*, Reactivating Catalytic Surface: Insights into the Role of Hot Holes in Plasmonic Catalysis, Small, 2018, 1703510 Lele Sun, Yanjing Gao, Yan Xu, Jie Chao, Huajie Liu, Lianhui Wang, Di Li*, Chunhai Fan, Real-Time Imaging of Single-Molecule Enzyme Cascade Using a DNA Origami Raft, J. Am. Chem. Soc. 2017, 139, 17525-17532 (highlighted by Nature Methods) Weiwei Qin, Tianhuan Peng, Yanjing Gao, Fei Wang, Xiaocai Hu, Kun Wang, Jiye Shi, Di Li*, Jicun Ren, Chunhai Fan, Catalysis-Driven Self-Thermophoresis of Janus Plasmonic Nanomotors, Angew. Chem. Int. Ed. 2017, 56, 515-518 Kun Li, Kun Wang, Weiwei Qin, Suhui Deng, Di Li*; Jiye Shi, Qing Huang, Chunhai Fan, DNA-Directed Assembly of Gold Nanohalo for Quantitative Plasmonic Imaging of Single-Particle Catalysis, J. Am. Chem. Soc. 2015, 137, 4292-4295 Yan Xu, Kun Li, Weiwei Qin, Bing Zhu, Ziang Zhou, Jiye Shi, Jun Hu, Chunhai Fan, Di Li*, Unraveling the Role of Hydrogen Peroxide in α Synuclein Aggregation Using an Ultrasensitive Nanoplasmonic Probe, Anal Chem. 2015, 87, 1968-1973 Tianhuan Peng, Weiwei Qin, Kun Wang, Jiye Shi, Chunhai Fan, Di Li*, Nanoplasmonic Imaging of Latent Fingerprints with Explosive RDX Residue, Anal. Chem. 2015, 87, 9403-9407 Kun Li, Weiwei Qin, Fan Li, Xinchun Zhao, Bowei Jiang, KunWang, Suhui Deng, Chunhai Fan*, Di Li*, Nanoplasmonic Imaging of Latent Fingerprints and Identification of Cocaine, Angew. Chem. Int. Ed. 2013, 52, 11542-11545 Yanqin Wen, Yan Xu, Xiuhai Mao, Yingliang Wei, Haiyun Song*, Nan Chen, Qing Huang, Chunhai Fan, Di Li*, DNAzyme-Based Rolling-Circle Amplification DNA Machine for Ultrasensitive Analysis of MicroRNA in Drosophila Larva, Anal. Chem. 2012, 84, 7664-7669 Xiaozue Zheng, Qing Liu, Chao Jing, Yang Li, Di Li*, Weijie Luo, Yanqin Wen, Yao He, Qing Huang, Yi-Tao Long, Chunhai Fan*, Catalytic Gold Nanoparticles for Nanoplasmonic Detection of DNA Hybridization, Angew. Chem. Int. Ed. 2011, 50, 11994-11998

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