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招生专业 083100-生物医学工程 招生方向 生物传感器 分子诊断 教育背景 2005-03--英国利兹大学 博士 2003-09--中国科学院研究生院 博士 1997-09--复旦大学医学院研究生院 硕士 工作简历 2005-03~现在, 英国利兹大学, 博士 2003-09~现在, 中国科学院研究生院, 博士 2000-07~现在, 中科院上海微系统与信息技术研究所, 硕士 1997-09~现在, 复旦大学医学院研究生院, 硕士 1985-07~现在, 河南省新乡医学院, 学士 奖励信息 (1) 上海市医学科技二等奖, 二等奖, 省级, 2020 专利成果 ( 1 ) 半定量同时检测才cTnI和Myo的免疫层析试纸条及其制备, 2011, 第 1 作者, 专利号: 2011101422740 ( 2 ) 一种基于核酸横向流试纸条检测单核苷酸多态性的方法, 2010, 第 1 作者, 专利号: 201010608280.6 ( 3 ) 基于量子点共振能量转移检测HBV DNA及单碱基突变的方法, 2010, 第 1 作者, 专利号: 201010003047.5 ( 4 ) 一种无需扩增基因组DNA的纳米探针芯片及检测方法, 2010, 第 1 作者, 专利号: ZL200710170616.3 ( 5 ) 一种纳米金结合聚噻吩衍生物比色检测目标靶DNA的方法, 2010, 第 1 作者, 专利号: 201010118181X ( 6 ) 一种基因芯片内参照、制备方法及其应用, 2010, 第 1 作者, 专利号: ZL200410089082.8 ( 7 ) 基于纳米探针的微流控芯片检测微量蛋白的方法, 2010, 第 3 作者, 专利号: 201010617918.2 ( 8 ) 一种基于非修饰单层石墨烯作为工作电极的纳米颗粒增强检测装置及其应用, 2015, 第 1 作者, 专利号: 201310371092.X ( 9 ) 一组人肺鳞癌诊断用LncRNA生物标志物, 2015, 第 1 作者, 专利号: 201510736882.2 ( 10 ) 一种基于双纳米金探针检测标志物的蛋白芯片, 2015, 第 1 作者, 专利号: 201510131861.8 ( 12 ) 一种肺癌早期检测用甲基化标志物及其检测方法, 2015, 第 3 作者, 专利号: 201510831357.9 ( 13 ) 一种基于量子点荧光共振能量转移检测基因甲基化程度的方法, 2015, 第 1 作者, 专利号: 201510263860.9 ( 14 ) 一种用于核酸单碱基改变的核酸反应理论分析方法, 2015, 第 1 作者, 专利号: 201510397820.3 ( 15 ) 一种基于热力学优化的双链置换核酸探针高特异性检测单碱基改变的方法, 2015, 第 1 作者, 专利号: 201510423384.2 ( 16 ) 一种基于纳米金探针结合基因芯片可视化检测microRNA的生物传感器, 2016, 第 1 作者, 专利号: CN 105463077 A ( 17 ) 一种观测微液滴的装置及方法, 2016, 第 3 作者, 专利号: CN 106053467 A ( 18 ) 一种定量检测癌胚抗原的免疫层析试纸条及其制备方法, 2016, 第 1 作者, 专利号: CN105891485A ( 19 ) 一种基于微球和微柱阵列芯片的乳滴数字PCR定量方法, 2016, 第 1 作者, 专利号: CN105838801A ( 20 ) 一种基于人结直肠癌特异性甲基化检测的引物及试剂盒, 2016, 第 2 作者, 专利号: CN 104164516 B ( 21 ) 一组人肺腺癌和人结直肠癌诊断用LncRNA 生物标志物, 2016, 第 1 作者, 专利号: CN 104131108 B ( 22 ) 基于滚环扩增比色检测靶核酸或蛋白的方法, 2014, 第 1 作者, 专利号: CN 102586450 B ( 23 ) 一种基于数字数字PCR芯片的基因甲基化程度定量方法, 2017, 第 1 作者, 专利号: 201710183073.2 ( 24 ) 一种基于多功能纳米级蛋白薄膜的石墨烯肿瘤标志物传感器及其制备方法, 2017, 第 1 作者, 专利号: 201710219519.2 ( 25 ) 一种基于PDMS材料的微室阵列式数字PCR芯片, 2017, 第 1 作者, 专利号: 201710334689.5 ( 26 ) 一种基于均匀分布的微球检测肿瘤标志物的微流控芯片及其使用方法, 2017, 第 1 作者, 专利号: 201710348153.9 ( 27 ) 一种基于多功能纳米级蛋白薄膜的石墨烯肿瘤标志物传感器及其制备方法, 2019, 第 1 作者, 专利号: 2017102195192 ( 28 ) 一种微腔式多色荧光数字PCR芯片及应用, 2019, 第 1 作者, 专利号: 201910166438X ( 29 ) 种外泌体分离与表面蛋白检测微流控装置及使用方法, 2019, 第 1 作者, 专利号: 201910540546.9 ( 30 ) 一种观测微液滴的装置及方法, 2019, 第 3 作者, 专利号: 2016104038384 发表著作 ( 1 ) 分子医学-基础与临床(上下册), Molecular Medicine: Basis and Clinical, 郑州大学出版社, 2010-08, 第 5 作者 Chapter 11:Long Non-Coding RNA in Non-Small cell Lung Cancers, INTECH, 2017-02, 第 2 作者 科研项目 ( 1 ) 指导胃癌用药的分子分型纳米检测器件与试剂研究, 主持, 国家级, 2017-07--2022-06 ( 2 ) 中药药物筛选药性研究用集成微流控系统, 主持, 国家级, 2018-01--2020-12 ( 3 ) 干细胞规模化培养的仿生材料遴选和生物反应器的智能化模块构建, 主持, 国家级, 2018-07--2022-12 ( 4 ) 针对新冠病毒快速核酸PCR检测的关键技术与设备, 主持, 国家级, 2020-05--2020-09 参与会议 (1)Sensitive detection of DNA hybridization based quantum dot-DNA conjugate probe chip Mao Hongju 2011-05-13 (2)基于量子点荧光探针芯片高灵敏检测心血管疾病相关基因多态性 纳米生物与医药技术专业委员会2010学术年会 毛红菊 2010-11-25 (3)Sensitive Detection of Target DNA Based on Nanoparticle Probe Chip MAO Hong-Ju 2010-05-17 (4)基于纳米探针的蛋白芯片研究 第二届全国纳米材料与结构、检测与表征研讨会 臧玉翠 2010-05-09

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

(1) A Novel Mass-Producible Capacitive Sensor with Fully Symmetric 3D Structure and Microfluidics for Cells Detection, Sensors, 2019, 通讯作者 (2) One-step hydrothermal synthesis of ultrabright water-soluble silicon nanoparticles for folate-receptor-mediated bioimaging, Journal of Materials Science, 2019, 通讯作者 (3) Black phosphorus based fiber optic biosensor for ultrasensitive cancer diagnosis, Biosensors and Bioelectronics, 2019, 第 4 作者 (4) Novel Graphene Biosensor Based on the Functionalization of Multifunctional Nano-bovine Serum Albumin for the Highly Sensitive Detection of Cancer Biomarkers, Nano-Micro Letters, 2019, 通讯作者 (5) A Microfluidic Platform for High-purity Separating Circulating Tumor Cells at the Single-cell Level, Talanta, 2019, 通讯作者 (6) Rapid Isolation and Multiplexed Detection of Exosome Tumor Markers Via Queued Beads Combined with Quantum Dots in a Microarray, Nano-Micro Letters, 2019, 通讯作者 (7) Absolute quantification and analysis of extracellular vesicle lncRNAs from the peripheral blood of patients with lung cancer based on multi-colour fluorescence chip-based digital PCR, Biosensors and Bioelectronics, 2019, 通讯作者 (8) Uniform distribution of microspheres based on pressure difference for carcinoma-embryonic antigen detection, Sensors and Actuators B: Chemical, 2018, 通讯作者 (9) Low-cost quantitative detection of nucleic acid using microbeads and microcolumn array chip, Sensors and Actuators B: Chemical, 2018, 通讯作者 (10) Absolute quantification of DNA methylation using microfluidic chip-based digital PCR, Biosensors and Bioelectronics, 2017, 通讯作者 (11) Identification of long noncoding RNAs for the detection of early stage lung squamous cell carcinoma by microarray analysis, Oncotarget, 2017, 通讯作者 (12) Multiplexed detection of lung cancer biomarkers in patients serum with CMOS-compatible silicon nanowire arrays, Biosensors and Bioelectronics, 2017, 通讯作者 (13) Label-free graphene biosensor targeting cancer molecules based on non-covalent modification, Biosensors and Bioelectronics, 2017, 通讯作者 (14) Detection of KRAS mutations using double-stranded toehold-exchange probes, Biosens Bioelectron, 2016, 通讯作者 (15) A panel of promoter methylation markers for invasive and noninvasive early detection of NSCLC using a quantum dots-based FRET approach, Biosens Bioelectron, 2016, 通讯作者 (16) DNA 功能化纳米金结合基因芯片可视化检测 microRNAs, 中国科学: 生命科学, 2016, 通讯作者 (17) Chip-based visual detection of microRNA using DNA-functionalized gold nanoparticles, SCIENCE CHINA Life Sciences, 2016, 通讯作者 (18) Highly sensitive and selective lateral flow immunoassay based on magnetic nanoparticles for quantitative detection of carcinoembryonic antigen, Talanta, 2016, 通讯作者 (19) Investigation of Controllable Nanoscale Heat-Denatured Bovine Serum Albumin Films on Graphene, Langmuir 2016, 32, 12623−12631, 2016, 通讯作者 (20) Highly sensitive detection of DNA methylation levels by using a quantum dot-based FRET method, Nanoscale, 2015, 通讯作者 (21) Absolute quantification of lung cancer related microRNA by droplet digital PCR, BiosensBioelectron, 2015, 通讯作者 (22) Identification of biomarkers for the detection of early stage lung adenocarcinoma by microarray profiling of long noncoding RNAs, Lung Cancer, 2015, 通讯作者 (23) Early detection of lung cancer in serum by a panel of microRNA biomarkers, Clin. Lung Cancer, 2015, 通讯作者 (24) Detection of Myocardial Injury Markers Based on Double Gold Nanoparticles Probes and Protein Chip, Chem. J. Chinese Universities, 2015, 通讯作者 (25) Ultrasensitive Detection of Dual Cancer Biomarkers with Integrated CMOS-Compatible Nanowire Arrays, Anal Chem., 2015, 第 4 作者 (26) Multi-nanomaterial electrochemical biosensor based on label-free graphene for detecting cancer biomarkers, BiosensBioelectron, 2014, 通讯作者 (27) Rolling circle amplification immunoassay combined with gold nanoparticle aggregates for colorimetric detection of protein, J. Nanosci. Nanotechno, 2014, 通讯作者 (28) Multi-nanomaterial electrochemical biosensor based on label-free raphene for detecting cancer biomarkers., Biosens Bioelectron., 2014, 通讯作者 (29) Signal-to-Noise Ratio Enhancement of Silicon Nanowires Biosensor with RollingCircle Amplification, Nano Lett., 2013, 通讯作者 (30) A colorimetric method for H1N1 DNA detection using rolling circle amplification, Analyst, 2013, 通讯作者 (31) Integrated biochip for label-free and real-time detection of DNA amplification by contactless impedance measurements based on interdigitated electrodes, BiosensBioelectron, 2013, 通讯作者 (32) Polyaniline/graphene-based electrochemical biosensor for sensitive detection of glucose, Asian Journal of Chemistry, 2013, 通讯作者 (33) Real-time monitoring of strand-displacement DNA amplification by a contactless electrochemical microsystem using interdigitated electrodes, Lab Chip, 2012, 通讯作者 (34) Evaluation of a modified lateral flow immunoassay for detection of high-sensitivity cardiac troponin I andmyoglobin, BiosensBioelectron, 2012, 通讯作者 (35) Evaluation of a modified lateral flow immunoassay for detection of high-sensitivity cardiac troponin I andmyoglobin, BiosensBioelectron, 2012, 通讯作者 (36) Detection of HBV DNA hybridization based on dual gold nano-probes, Chemical Journal of Chinese University, 2012, 通讯作者 (37) A lateral flow biosensor for sensitive and rapid detection of BNP and NT- proBNP., The 22nd Anniversary World Congress on Biosensors, 2012, 通讯作者 (38) A Visual High-Sensitivity Microarray for Detection of Hepatitis B Virus DNA and Its Single Nucleotide, Chin J Anal Chem, 2012, 通讯作者 (39) Sensitive visual detection of protein based on a rolling circle amplification immunoassay and gold nanoparticle aggregation, The 4th Sino-German Workshop of Cooperation, 2012, 通讯作者 (40) Simultaneous Detection of High-Sensitivity Cardiac Troponin I and Myoglobin by Modified Sandwich Lateral Flow Immunoassay., Clin Chem., 2011, 通讯作者 (41) Label-free optical detection of single-base mismatches by the combination of nuclease and gold nanoparticles, BiosensBioelectron, 2011, 通讯作者 (42) The Application of Nanomaterials in Biomedical Detection, China Biotechnology, 2011, 通讯作者 (43) Photoluminescence properties of Re(I) complex doped composite submicron fibers prepared by electrospinning, Spectrochim Acta A Mol Biomol Spectrosc, 2011, 通讯作者 (44) Sensitive detection of DNA hybridization based on quantum dot-DNA conjugates arrays, CFWBET, 2011, 通讯作者 (45) QDs-DNA nanosensor for the detection of hepatitis B virus DNA and thesingle-base mutants, Biosensors and Bioelectronics, 2010, 通讯作者 (46) Detection of Hepatitis B Virus Deoxyribonucleic Acid Based on Gold Nanoparticle Probe Chip, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2010, 通讯作者 (47) Clinical evaluation of a colorimetric oligonucleotide chip for genotyping hepatitis C virus, Clinical Biochemistry, 2010, 通讯作者 (48) 基于纳米金比色检测 NOS1AP基因单碱基突变, 高等学校化学学报, 2010, 通讯作者 (49) 纳米探针芯片技术用于微量乙肝病毒DNA的检测, 分析化学, 2010, 通讯作者 (50) Label-Free Colorimetric Assay Based on Gold Nanoparticles in Detection of NOS1AP with Single Nucleotide Polymorphism, Chem J Chinese U, 2010, 通讯作者 (51) Sensitive Detection of Target DNA Based on Nanoparticle Probe Chip, The 2th Sino-German Workshop of Cooperation, 2010, 通讯作者 (52) Array with quantum dot-DNA conjugate probe for detection single-base mutation, 20thAnniversary World Congress on Biosensors, 2010, 通讯作者 (53) Fluorescence resonance energy transfer based quantum dot-DNA conjugate for sensitive detection of hepatitis B virus DNA, Proceedings of the 6’th International Forum on Post-genome Technologyies(IFPT’6) ISTP, 2009, 通讯作者 (54) Label-free colorimetric screening ofnuclease activity and substrates by using unmodified gold nanoparticles., Chembiochem, 2009, 通讯作者 (55) Colorimetric oligonucleotide array for Genotyping of Hepatitis C Virus based on the 5’Noncoding Region, Clinica Chimica Acta, 2008, 通讯作者 (56) Direct Molecular Detection of Hepatitis B Virus DNA by Nanoparticle-Based Biobarcode Amplification Assay, Biosensors The Tenth World Congress on Biosensors, Shanghai, 2008, 通讯作者 (57) Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2, J Biol Chem, 2008, 通讯作者 (58) Identification of key residues coordinating functional inhibition of P2X7 receptors by zinc and copper, Mol Pharmacol, 2007, 通讯作者 (59) DNA Array with nanoparticle probes for the detection of P53 mutations of Lung Cancer, The 6th China InternationalNanoScience and Technology Symposium, Chengdu, 2007, 通讯作者

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