个人简介
张晓哲,研究员,博士生导师,18T3组组长,2004于中国科学院大连化学物理研究所获得分析化学博士学位,2005年受德国马普协会奖学金资助在生物控制论研究所(MaxPlanckInstituteforBiologicalCybernetics)做博士后研究,2009年在瑞士弗里堡大学(UniversityofFribourg)博士后研究,担任研究小组组长,2014年获得马普伙伴小组计划支持。
研究领域
研究方向
研究工作主要涉及复杂体系特别是神经化学物质的分析、分离和功效研究。重点是研究病理状态与信号分子的关系,为痴呆症等神经退行性疾病的早期诊断和治疗提供有力的支持。
近期论文
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1.SaraFalasca,VaclavRanca,FilomenaPetruzziello,AbbasKhania,RobertKretza,XiaozheZhang*,GregorRainer.Alteredneurochemicallevelsintheratbrainfollowingchronicnicotinetreatment.JournalofAnatomicalChemistry,2014,59-60C:29-35.
2.XiaozheZhang,FilomenaPetruzziello,GregorRainer*.Extendingthescopeofneuropeptidomicsinthemammalianbrain.EuPAOpenProteomics,2014,3,273.
3.FilomenaPetruzziello,SaraFalasca,RobertKretz,PerAndren,GregorRainer,XiaozheZhang*.Chronicnicotineregulatesneuropeptidesinratstriatum.MolecularandCellularProteomics.2013,12(6):1553-62.
4.XiaozheZhang*,FilomenaPetruzziello,FabioZani,LaetitiaFouillen,PerE.Andren,GiovanniSolinas,GregorRainer.Highidentificationratesofendogenousneuropeptidesfrommousebrain.JournalofProteomeResearch.2012,11(5):2819-27.
5.FilomenaPetruzziello,LaetitiaFouillen,HenrikWadensten,RobertKretz,PerAndren,GregorRainer,XiaozheZhang*.ExtensiveCharacterizationofTupaiabelangeriNeuropeptidomeUsinganIntegratedMassSpectrometricApproach.JournalofProteomeResearch.2012,11(2):886-96.
6.LaetitiaFouillen,FilomenaPetruzziello,RobertKretz,XiaozheZhang*,GregorRainer.Neuropeptidealterationsinthetreeshrewhypothalamusduringvolatileanesthesia.JournalofProteomics,2013,80:311-9.
7.VaclavRanc,FilomenaPetruzziello,RobertKretz,EnrikeG.Argando?a,XiaozheZhang*,GregorRainer.Broadcharacterizationofendogenouspeptidesinthetreeshrewvisualsystem.JournalofProteomics.2012,75(9):2526-35.
8.JuanLi,VeronikavonPf?stl,DanielZaldivar,XiaozheZhang*,NikosLogothetisandAlexanderRauch*.Measuringmultipleneurochemicalsandrelatedmetabolitesinbloodandbrainoftherhesusmonkeybyusingdualmicrodialysissamplingandcapillaryhydrophilicinteractionchromatography-massspectrometry.AnalyticalandBioanalyticalChemistry.2012,402(8):2545-54.
9.SaraFalasca,FilomenaPetruzziello,RobertKretz,GregorRainer,XiaozheZhang*.Semi-quantificationofMultipleQuaternaryAmmoniumsintheBrainUsingTandemCapillaryColumnSeparationandHighResolutionMassSpectrometricDetection.JournalofChromatographyA.2012,1241:46-51.