研究领域
1.具有重要生物活性天然化合物的发现与研究
2.天然产物化学生物学研究
3.中药复方与系统生物学研究
4.中药质量控制方法学研究
5.中药新药研究
近期论文
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Jing Zhao, Peng Jiang and Weidong Zhang. Molecular networks for the study of TCM Pharmacology. Briefings in Bioinformatics, 2010, 11(4): 417-430.
Jing Zhao, Chao Geng, Lin Tao, Duanfeng Zhang, Hong Yu, Weidong Zhang, Yixue Li,and Zhiwei Cao. Reconstruction and analysis of human liver-specific metabolic network based on CNHLPP data. Journal of Proteome Research. 2010, 9 (4):1648-1658.
Jiang Jiang Qin, Li Yan Wang, Jia Xian Zhu, Hui Zi Jin, Jian Jun Fu, Xiao Feng Liu, Hong Lin Li, and Wei Dong Zhang. Neojaponicone A, A Bioactive Sesquiterpene Lactone Dimer with an Unprecedented Carbon Skeleton from Inula japonica. Chem. Comm. DOI: 10.1039/C0CC03572F (2010).
Xian-Wen Yang, Su-Mei Li, Liang Wu, Yongli LI, Lin Feng, Yunheng Shen, Junmian Tian, Jian Tang, Ning Wang, Yonghong Liu and Wei-Dong Zhang. Abiesatrines A–J: anti-inflammatory and antitumor triterpenoids from Abies georgei Orr. Organic & Biomolecular Chemistry, 2010, 8, 2609–2616.
Li-Yue Nie, Jiang-Jiang Qin, Lan Yan, Yu-Bo Liu, Yue-Xing Pan, Hui-Zi Jin and Wei-Dong Zhang. Sesquiterpenoids from Inula lineariifolia inhibit nitric Oxide production. Journal of Natural Products, 2010,73:1117-1120.
Chun-Mei Liu, Bo Li, Yun-Heng Shen, Wei-Dong Zhang. Heterocyclic Compounds and Aromatic Diglycosides from Bretschneidera sinensis. Journal of Natural Products, 2010, 73(9)1582-1585.
Shuang Liang, Yun-Heng Shen, Yi Feng, Jun-Mian Tian, Xiao-Hua Liu, and Wei-Dong Zhang. Terpenoids from Daphne aurantiaca and their inhibitory activities against NO production. Journal of Natural Products, 2010, 73: 532-535.
Jiang Jiang Qin , Hui Zi Jin , Jian Jun Fu , Xiao Jia Hu, Yan Wang, Shi Kai Yan ,Wei Dong ZHANG. Corrigendum to “Japonicones A–D, bioactive dimeric sesquiterpenes from Inula japonica Thunb.” Bioorganic Medicinal Chemistry letters, 2010,20:5584.
Junmian Tian, Yunheng Shen, Xianwen Yang, Shuang Liang, Weidong Zhang. Tunicyclin A, the First Plant Tricyclic Ring Cycloheptapeptide from Psammosilene tunicoides. Organic Letters, 2009, 11 (5), 1131-1133.
Zhong-ying Lin, Hai-bing Meng, Shi-kai Yan, Ping-bo Xu, Gen-jin Yang, Wei-xing Dai, Wei-Dong Zhang, and Xiao-ming Deng. A metabonomic approach to early prognostic evaluation of experimental sepsis by 1H NMR-based and pattern recognition. NMR in Biomedicine, 2009, 22: 601-608.
Shikai Yan, Bin Wu, Zhongying Lin, Yun Yang, Jianhua Huang, Ziyin Shen and Weidong Zhang. Metabonomic characterization of aging and investigation on the anti-aging effects of total flavones of Epimedium. Molecular Biosystems, 2009, 5, 1204-1213.
Juan Su , Chuan Zhang , Wei Zhang , Yun-heng Shen , Hui-liang Li , Run-hui Liu , Xi Zhang, Xiao-Jia Hu , Wei-Dong Zhang . Qualitative and quantitative determination of the major coumarins in Zushima by high performance liquid chromatography with diode array detector and mass spectrometry. Journal of Chromatography A, 2009,1216:2111-2117.
Sheng Lin, Yun-heng Shen,Hui-liang Li,Xian-wen Yang, Long-hai Lu, Zheng-sheng Huang, Run-hui Liu, Xi-ke Xu, Wei-Dong Zhang. Acylated Iridoids with Cytotoxicity from(IF=3.159)
Peng Fu, Sheng Lin , Jian Tang , Yun-Heng Shen, Xi Zhang, Wei-Dong Zhang. Constituents of the moss Polytrichum commune. Journal of Natural Products, 2009, 72:1335-1337.
Yong-Li Li, Xian-Wen Yang, Su-Mei Li, Yun-Heng Shen, Xiao-Hua Liu, Jian Tang, and Wei-Dong Zhang. Terpenoid Constituents of Abies chensiensis. Journal of Natural Products ,2009,72:1065-1068.