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研究领域

新型药物控制释放系统的构建。荧光探针及其在生物分析、医学诊断及环境监测中的应用。

近期论文

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Zhenlin Tian, Weiping Zhu*, Yufang Xu*, and Xuhong Qian. Unnatural Amino Acid Based Fluorescent Probe for Phenylalanine Ammonia Lyase, Org. Biomol. Chem., 2014, 12, 5818-5821 殷丽艳,陈甜甜,朱维平. 基于萘酰亚胺的Turn-On型Fe(III)荧光探针,影像科学与光化学,2014, 32(1): 84-90 Mengjie Chen, Chusen Huang, Chunsheng He, Weiping Zhu*, and Yufang Xu. A Novel Controlled-Release System Based on Horseradish Peroxidase-Gated Mesoporous Silica Nanocontainers. J. Control. Release, 2013, 172(1), e73–e74 Liyan Wang, Chunmei Yang, Weiqiang Lu, Li Liu, Rui Gao, Sha Liao, Zhenjiang Zhao, Lili Zhu, Yufang Xu, Honglin Li*, Jin Huang*, Weiping Zhu*, Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening, Bioorg. Med. Chem. Lett., 2013, 23, 3496–3499 Qin Yin, Chusen Huang, Chao Zhang, Weiping Zhu,* Yufang Xu,*Xuhong Qian and Yi Yang*, In situ visualization and detection of protein sulfenylation responses in living cells through a dimedone-based fluorescent probe, Org. Biomol. Chem., 2013,11(43), 7566-7573 Chusen Huang, Qin Yin,Jiangjiang Meng, Weiping Zhu*,Yi Yang,Xuhong Qian and Yufang Xu*. Versatile Probes for Selective Detection of Vicinal-Dithiol-Containing Proteins (VDPs): Design, Synthesis and Application in living cells. Chem. Eur. J., 2013, 19(24), 7739-7747 Mengjie Chen, Chusen Huang, Chunsheng He, Weiping Zhu*, Yufang Xu, and Yunfeng Lu, Glucose-Responsive Controlled Release System Using Glucose Oxidase-Gated Mesoporous Silica Nanocontainers, Chem. Commun., 2012, 48(76), 9522-9524. Liyan Yin, Chunsheng He, Chusen Huang, Weiping Zhu*, Xin Wang, Yufang Xu* and Xuhong Qian*, A pH and Temperature Dual Responsive Polymeric Fluorescent Sensor and Its Imaging in Living Cells, Chem. Commun., 2012, 48(37), 4486-4488 黄楚森,朱维平*, 徐玉芳*, 钱旭红, 蛋白质巯基及其氧化性修饰的化学检测方法, 药学学报, 2012, 47(3): 280?290 Chusen Huang, Qin Yin, Weiping Zhu*, Yi Yang*, Yufang Xu*, Xin Wang, and Xuhong Qian. Highly selective fluorescent probe for vicinal dithiol-containing proteins and in-situ imaging in living cells. Angew. Chem. Int. Ed., 2011, 50, 7551-7556 Chunsheng He, Xuhong Qian*, Yufang Xu, Chunmei Yang, Liyan Yin, Weiping Zhu*. A Ratiometric Fluorescent Probe for Oxalate Based on Alkyne-conjugated Carboxamido- quinolines in Aqueous Solution and Imaging in Living Cells. Dalton Trans., 2011, 40, 1034-1037 Chunsheng He, Weiping Zhu*, Yufang Xu, Ye Zhong, Juan Zhou and Xuhong Qian*. Ratiometric and Reusable Fluorescent Nanoparticles for Zn2+ and H2PO4- Detection in Aqueous Solution and Living Cell, J. Mater. Chem., 2010, 20, 10755-10764 Tao Chen, Weiping Zhu*, Yufang Xu, Shenyi Zhang, Xiaojun Zhang, Xuhong Qian. A Thioether-Rich Crown-Based Highly Selective Fluorescent Sensor for Hg2+ and Ag+ in Aqueous Solution, Dalton Trans., 2010, 39, 1316-1320. Chunsheng He, Weiping Zhu*, Yufang Xu, Xuhong Qian*, Tao Chen. Trace Mercury (II) Detection and Separation in Serum and Water Samples Using a Reusable Bifunctional Fluorescent Sensor, Anal. Chim. Acta, 2009, 651, 227-233 Weiping Zhu, Min Dai, Yufang Xu*, Xuhong Qian*. Novel Nitroheterocyclic Hypoxic Markers for Solid Tumor: Synthesis and Biological Evaluation, Bioorg. Med. Chem., 2008, 16, 3255-3260 朱维平,徐玉芳,钱旭红*. 具有重要生物学意义的重金属及过渡金属荧光分子传感器,化学进展, 2007, 19, 1229-123

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