叶金星 - 华东理工大学

研究领域

1. 合成化学：新试剂、新催化剂、新反应的设计与发现，及其在有机合成中的应用；不对称催化合成的立体选择性研究新策略。 2. 药物化学：活性天然产物的全合成与构效关系研究。 3. 过程化学：手性药物及中间体、天然药物的合成新方法研究及其过程化学开发。

近期论文

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Kaihe Zou, Jinxing Ye, Xin-Yan Wu, Acid-catalyzed Efficient Friedel–Crafts Reaction of Indoles with N-Boc Aminals, Tetrahedron, 2015, 71, 7869-7873. Kaihe Zou, Jinxing Ye, Xin-Yan Wu, An Efficient Synthesis of Styrenyl Enamides from 4-Aryl-2-Oxazolidinones in the Presence of Strong Base, Tetrahedron Letters, 2015, 56, 5517-5520. Xiaodong Gu, Tingting Guo, Yuanyuan Dai, Allegra Franchino, Jie Fei, Chuncheng Zou, Darren J. Dixon and Jinxing Ye, Direct Catalytic Asymmetric Doubly Vinylogous Michael Addition of α,β-Unsaturated γ-Butyrolactams to Dienones, Angew. Chem. Int. Ed., 2015, DOI: 10.1002/anie.201504276. Fei Wang, Na Zhu, Pinhong Chen, Jinxing Ye, and Guosheng Liu, Copper-Catalyzed Trifluoromethylazidation of Alkynes: Efficient Access to CF3-Substituted Azirines and Aziridines, Angew. Chem. Int. Ed., 2015, DOI: 10.1002/anie.201503412. Xinxin Wu, Chunna Meng, Xiaoqian Yuan, Xiaotong Jia, Xuhong Qian and Jinxing Ye, Transition-Metal-Free Visible-Light Photoredox Catalysis at Room-Temperature for Decarboxylative Fluorination of Aliphatic Carboxylic Acids by Organic Dyes, Chem. Commun., 2015, 51, 11864–11867. Na Zhu, Fei Wang, Pinhong Chen, Jinxing Ye, and Guosheng Liu, Copper-Catalyzed Intermolecular Trifluoromethylazidation and Trifluoromethylthiocyanation of Allenes: Efficient Access to CF3-Containing Allyl Azides and Thiocyanates, Org. Lett., 2015, 17, 3580–3583. Yuan Wei, Shigang Wen, Zunwu Liu, Xinxin Wu, Bubing Zeng, and Jinxing Ye, Diastereodivergent Catalytic Asymmetric Michael Addition of 2-Oxindoles to α,β-Unsaturated Ketones by Chiral Diamine Catalysts, Org. Lett., 2015, 17, 2732–2735. Haoxiang Hu, Chunna Meng, Yun Dong, Xin Li, and Jinxing Ye, Catalytic Asymmetric Formal Aza-Diels–Alder Reactions of α,β-Unsaturated Ketones and 3H-Indoles, ACS Catal., 2015, 5, 3700–3703. Xiaodong Gu, Yuanyuan Dai, Tingting Guo, Allegra Franchino, Darren J. Dixon, and Jinxing Ye, A General, Scalable, Organocatalytic Nitro-Michael Addition to Enones: Enantioselective Access to All-Carbon Quaternary Stereocenters, Org. Lett., 2015, 17, 1505-1508. Xin Li, Min Lu, Yun Dong, Wenbin Wu, Qingqing Qian, Jinxing Ye & Darren J Dixon, Diastereodivergent Organocatalytic Asymmetric Vinylogous Michael Reactions, Nature Communications, 2014, 5, 4479. Jiabin Xu, Xin Mu, Pinhong Chen, Jinxing Ye, and Guosheng Liu, Copper-Catalyzed Trifluoromethylthiolation of Aryl Halides with Diverse Directing Groups, Org. Lett., 2014, 16, 3942–3945. Junzhu Lu, Jinxing Ye, Wei-Liang Duan, Palladium-Catalyzed Asymmetric 1,6-Addition of Diarylphosphines to alpha, beta, gamma, delta-Unsaturated Sulfonic Esters: Controlling Regioselectivity by Rational Selection of Electron-Withdrawing Groups, Chem. Commun., 2014, 50, 698-700. Junzhu Lu, Jinxing Ye, Wei-Liang Duan, Palladium-Catalyzed Asymmetric Addition of Diarylphosphines to alpha,beta-Unsaturated Sulfonic Esters for the Synthesis of Chiral Phosphine Sulfonate Compounds, Org. Lett., 2013, 15, 5016-5019. Wenbin Wu, Xiaoqian Yuan, Juan Hu, Xinxin Wu, Yuan Wei, Zunwu Liu, Junzhu Lu, Jinxing Ye, Catalytic Asymmetric Construction of Chiral Hydropyridazines via Conjugate Addition of N-Monosubstituted Hydrazones to Enones, Org. Lett., 2013, 15, 4524–4527. Huicai Huang, Wenbin Wu, Kailong Zhu, Juan Hu, Jinxing Ye, Highly Diastereo- and Enantioselective Cross-Cascade Reactions of Different Enones, Chem. Eur. J., 2013, 19, 3838-3841. Kailong Zhu, Huicai Huang, Wenbin Wu, Yuan Wei, Jinxing Ye, Aminocatalyzed Asymmetric Diels–Alder Reaction of 2,4-Dienals and Rhodanine/Hydantoin Derivatives, Chem. Commun., 2013, 49, 2157-2159. Wenbin Wu, Xin Li, Huicai Huang, Xiaoqian Yuan, Junzhu Lu, Kailong Zhu, Jinxing Ye, Asymmetric Intramolecular Oxa-Michael Reactions of Cyclohexadienones Catalyzed by a Primary Amine Salt, Angew. Chem. Int. Ed., 2013, 52, 1743–1747. Wenbin Wu, Huicai Huang, Xiaoqian Yuan, Kailong Zhu, Jinxing Ye, Asymmetric Construction of Spirocyclohexanonerhodanines Catalyzed by Simple Diamine Derived from Chiral tert-Leucine, Chem. Commun., 2012, 48, 9180–9182. Feng Yu, Haoxiang Hu, Xiaodong Gu, Jinxing Ye, Asymmetric Michael Addition of Substituted Rhodanines to α,β-Unsaturated Ketones Catalyzed by Bulky Primary Amines, Org. Lett., 2012, 14, 2038–2041. Huicai Huang, Kailong Zhu, Wenbin Wu, Zhichao Jin, Jinxing Ye, Highly Diastereoselective and Enantioselective Michael Addition of 5H-Oxazol-4-ones to α, β-Unsaturated Ketones Catalyzed by a New Bifunctional Organocatalyst with Broad Substrate Scope and Applicability, Chem. Commun., 2012, 48, 461-463. Xiaoyan Luo, Zhiqiang Zhou, Xin Li, Xinmiao Liang, Jinxing Ye, Enantioselective Organocatalytic Phospha-Michael Reaction of α,β-Unsaturated Aldehydes, RSC Advances, 2011, 1, 698–705. Wenjun Li, Xin Li, Wenbin Wu, Xinmiao Liang, Jinxing Ye, Highly Diastereo- and Enantioselective One-Pot Michael-Aldol Reactions of α, β-Unsaturated Aldehydes with Imidazole Derivatives, Chem. Commun., 2011, 47, 8325–8327. Juanjuan Yang, Huicai Huang, Zhichao Jin, Wenbin Wu, Jinxing Ye, Diastereoselective Synthesis of Bicyclo[2.2.2]octan-2-one Derivatives through An Unexpected Organocatalytic Tandem Michael-Michael Reaction, Synthesis, 2011, 1984-1987. Wenjun Li, Xin Li, Tingting Ye, Wenbin Wu, Xinmiao Liang, Jinxing Ye, Asymmetric Organocatalytic Michael/α-Alkylation Reaction of α, β-Unsaturated Aldehyde with Chloroacetophenone, Tetrahedron Lett., 2011, 52, 2715-2718. Xiaoyan Luo, Zhiqiang Zhou, Feng Yu, Xin Li, Xinmiao Liang, and Jinxing Ye, Asymmetric Vinylogous Michael Reaction of α, β-Unsaturated Aldehyde with Buteno-4-lactone, Chem., Lett., 2011, 40, 518-520. Huicai Huang, Zhichao Jin, Kailong Zhu, Xinmiao Liang, Jinxing Ye, Highly Diastereo- and Enantioselective Synthesis of 5-Substituted 3-Pyrrolidin-2-Ones through A Direct Vinylogous Michael Addition under Multifunctional Catalysis, Angew. Chem. Int. Ed., 2011, 50, 3232-3235.