朱丽丽 - 华东理工大学

研究领域

主要从事与疾病有关蛋白质的结构生物学和化学生物学方面研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Junsheng Zhu, Le Han, Yanyan Diao, Xiaoli Ren, Minghao Xu, Liuxin Xu, Shiliang Li, Qiang Li , Dong Dong, Jin Huang, Xiaofeng Liu, Zhenjiang Zhao, Rui Wang, Lili Zhu*, Yufang Xu, Xuhong Qian *, and Honglin Li*.Design, Synthesis, X-ray Crystallographic Analysis, and Biological Evaluation of Thiazole Derivatives as Potent and Selective Inhibitors of Human Dihydroorotate Dehydrogenase. J. Med. Chem. 2015, 58（3）, 1123-1139. Liyan Wang, Shoude Zhang, Junsheng Zhu, Lili Zhu, Xiaofeng Liu, Lei Shan, Jin Huang*, Weidong Zhang*, Honglin Li*. Identification of Diverse Natural Products as Falcipain-2 Inhibitors through Structure-based Virtual Screening. Bioorg. Med. Chem. Lett. 2014. 24(5) : 1261–1264. Minghao Xu, Junsheng Zhu, Yanyan Diao, Hongchang Zhou, Xiaoli Ren, Deheng Sun, Jin Huang, Dongmei Han, Zhenjiang Zhao, Lili Zhu*, Yufang Xu*, and Honglin Li*. Novel Selective and Potent Inhibitors of Malaria Parasite Dihydroorotate Dehydrogenase: Discovery and Optimization of Dihydrothiophenone Derivatives. J. Med. Chem., 2013. 56 (20) : 7911–7924 Xiaojuan Yu, Xue Zhao, Lili Zhu, Chuanxin Zou, Xiaofeng Liu, Zhenjiang Zhao, Jin Huang* and Honglin Li*. Discovery of novel inhibitors for human farnesyltransferase (hFTase) via structure-based virtual screening. Med. Chem. Commun., 2013. 4 : 962-971 Liyan Wang, Chunmei Yang, Weiqiang Lu, Li Liu, Rui Gao, Sha Liao, Lili Zhu, Zhenjiang Zhao, Yufang Xu, Honglin Li*, Jin Huang, Weiping Zhu. Discovery of New Potent Inhibitors for Carbonic Anhydrase IX by Structure-Based Virtual Screening. Bioorg. Med. Chem. Lett.., 2013. 23 : 3496-3499 Yuwei Song, Huangtao Jin, Xiaofeng Liu, Lili Zhu*, Jin Huang*, Honglin Li*. Discovery of non-peptide inhibitors of Plasmepsin II by structure-based virtual screening. Bioorg. Med. Chem. Lett., 2013. 23(7) : 2078-2082 Xianwen Cao, Jing Jiang, Shoude Zhang, Lili Zhu, Juan Zou, Yanyan Diao, Weilie Xiao, Lei Shan, Handong Sun, Weidong Zhang*, Jin Huang*, Honglin Li*. Discovery of Natural Estrogen Receptor Modulators with Structure-based Virtual Screening. Bioorg. Med. Chem. Lett., 2013. 23 : 3329-3333 Kunqiang Cui1, Weiqiang Lu1, Lili Zhu1, Xu Shen, Jin Huang. Caffeic acid phenethyl ester (CAPE), an active component of propolis, inhibits Helicobacter pulori peptide deformylase activity. Biochem. Biophys. Res. Commun., 2013. 435(2):289-294 Lili Zhu, Shyla George, Marco F.Schmidt, Samer I Al-Gharabli, Jorg Rademann, Rolf Hilgenfeld. Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease. Antiviral research. 2011, 92 (2)，204-216. Lili Zhu, Cai Yuan, Zhuo Chen, Wanyu Wang, Mingdong Huang. Expression, purification and characterization of recombinant Jerdonitin, a P-II class snake venom metalloproteinase comprising metalloproteinase and disintegrin domains. Toxicon, 2010, 55, 375-380. Lili Zhu, Feng Yang, Liqing Chen, Edward J.Meehan, Mingdong Huang. A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography. Journal of structural biology.2008, 162, 40-49.