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Wei Zhou, Xiaofeng Liu, Zhengchao Tu, Xin Ku, Fang Bai, Zhenjiang Zhao, Ke Ding,, Honglin Li, Yufang Xu; Scaffold hopping via hybrid molecular 3D similarity, a successful paradigm for design and optimization of novel irreversible inhibitors targeting epidermal growth factor receptor (EGFR) tyrosine kinase T790M/L858R Mutant; J. Med. Chem. 2013(online).
Minghao Xu, Junsheng Zhu, Yanyan Diao, Hongchang Zhou, Xiaoli Ren, Deheng Sun, Jin Huang, Zhenjiang Zhao, Lili Zhu,*, Honglin Li,*, Yufang Xu,*; Novel, Selective and Potent Inhibitors of Malaria Parasite Dihydroorotate Dehydrogenase; J. Med. Chem. 2013, 56, 7911?7924.
Jun Yuan, Ye Zhong, Shiliang Li, Xue Zhao, Guoqin Luan, Zhenjiang Zhao, Jin Huang, Honglin Li, and Yufang Xu; Triazole and Benzotriazole Derivatives as Novel Inhibitors for p90 Ribosomal S6 Protein Kinase 2: Synthesis, Molecular Docking and SAR Analysis; Chin. J. Chem. 2013, 31, 1192-1198.
Jun Yuan, Zhenjiang Zhao*, Weiping Zhu, Honglin Li, Xuhong Qian, Yufang Xu; New strategy for the synthesis of 2-phenylbenzimidazole derivatives with sodium perborate (SPB) as oxidant; Tetrahedron,69 (34), (2013) , 7026-7030. （通讯作者）
Liyan Wang, Chunmei Yang , Weiqiang Lu, Li Liu, Rui Gao, Sha Liao, Zhenjiang Zhao, Lili Zhu, Yufang Xu, Honglin Li, Jin Huang, Weiping Zhu；Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening；Bioorganic & Medicinal Chemistry Letters 23 (2013) 3496–3499.
Xiaojuan Yu, Xue Zhao, Lili Zhu, Chuanxin Zou, Xiaofeng Liu, Zhenjiang Zhao, Jin Huang* and Honglin Li*. Discovery of novel inhibitors for human farnesyltransferase (hFTase) via structure-based virtual screening. Med. Chem. Commun., 2013. 4:962-971.
Rui Gao, Sha Liao, Chen Zhang, Weilong Zhu, Liyan Wang, Jin Huang, Zhenjiang Zhao, Honglin Li, Xuhong Qian, Yufang Xu. Structure-Activity Relationships and Optimization of Heterocyclic Substituted Benzene Sulfonamides as Novel Cabonic Anhydrase IX Inhibitors. European Journal of Medicinal Chemistry. 62 (2013), 597-604. （通讯作者）
Ye Zhong, Mengzhu Xue, Weiqiang Lu, Jin Huang, Honglin Li, Xiaofeng Liu, Zhenjiang Zhao, Yufang Xu. Substituted Indolin-2-ones as p90 Ribosomal S6 Protein Kinase 2 (RSK2) Inhibitors: Molecular docking simulation and structure-activity relationship analysis.Bioorg. Med. Chem. (2013) 1724–1734.（通讯作者）
Mengzhu Xue, Jun Yuan, Bin Wu, Xue Zhao, Xiaofeng Liu, Jin Huang, Zhenjiang Zhao, Honglin Li, Yufang Xu. Novel inhibitors for p90 ribosomal S6 protein kinase 2: design, synthesis and SAR. Journal of Chinese Pharmaceutical Sciences 21 (2012) 401–408. （通讯作者）
Yanyan Diao, Weiqiang Lu, Huangtao Jin, Junsheng Zhu, Le Han, Minghao Xu, Rui Gao, Xu Shen, Zhenjiang Zhao, Xiaofeng Liu, Yufang Xu, Jin Huang, and Honglin Li. Discovery of Diverse Human Dihydroorotate Dehydrogenase Inhibitors as mmunosuppressive Agents by Structure-Based Virtual Screening. J. Med. Chem. 2012, 55, 8341?8349.
Mengzhu Xue, Xianwen Cao, Ye Zhong, Dong Kuang, Xiaofeng Liu, Zhenjiang Zhao and Honglin Li. Insulin-like Growth Factor-1 Receptor (IGF-1R) Kinase Inhibitors in Cancer Therapy: Advances and Perspectives. Current Pharmaceutical Design,2012, 18, 2901-2913.
Mengzhu Xue, Minghao Xu, Weiqiang Lu, Jin Huang, Honglin Li, Yufang Xu, Xiaofeng Liu, and Zhenjiang Zhao. Synthesis, activity evaluation, and docking analysis of barbituric acid aryl hydrazone derivatives as RSK2 inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry, 2013; 28(4): 747–752.（通讯作者）
Qingshan Du, Weiping Zhu, Zhenjiang Zhao, Xuhong Qian, and Yufang Xu. Novel Benzo-1,2,3-thiadiazole-7-carboxylate Derivatives As Plant Activators and the Development of Their Agricultural Applications. J. Agric. Food Chem. 2012, 60, 346?353.（通讯作者）
Fang Bai, Hongyan Liu, Linjiang Tong, Wei Zhou, Li Liu, Zhenjiang Zhao, Xiaofeng Liu, Hualiang Jiang, Xicheng Wang, Hua Xie, Honglin Li. Discovery of novel selective inhibitors for EGFR-T790M/L858R. Bioorganic & Medicinal Chemistry Letters 22 (2012) 1365–1370.
Shiliang Li, Yi Zhou, Weiqiang Lu, Ye Zhong, Wenlong Song, Kangdong Liu, Jin Huang, Zhenjiang Zhao, Yufang Xu, Xiaofeng Liu, and Honglin Li. Identification of Inhibitors against p90 Ribosomal S6 Kinase 2 (RSK2) through Structure-Based Virtual Screening with the Inhibitor-Constrained Refined Homology Model. J. Chem. Inf. Model. 2011, 51, 2939–2947.
Huameng Li, Aiguo Liu, Zhenjiang Zhao, Yufang Xu, Jiayuh Lin, David Jou, and Chenglong Li. Fragment-Based Drug Design and Drug Repositioning Using Multiple Ligand simultaneous Docking (MLSD): Identifying Celecoxib and Template Compounds as Novel Inhibitors of Signal Transducer and Activator of Transcription 3 (STAT3). J. Med. Chem. 2011, 54, 5592–5596.
Weiqiang Lu, Xiaofeng Liu, Xianwen Cao, Mengzhu Xue, Kangdong Liu, Zhenjiang Zhao, Xu Shen, Hualiang Jiang, Yufang Xu, Jin Huang, and Honglin Li. SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2. Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors To Suppress Cell Migration. J. Med. Chem. 2011, 54, 3564–3574.
Weiping Zhu, Zhenjiang Zhao, Yufang Xu,*Derivatives of Benzothiadiazole-7-Carboxylates: Synthesis and Biological Activity，Monatshefte fur Chemie，2008，39，1067-1071.
Zhenjiang Zhao, Z-Y. James Zhan, Development of new ruthenium catalysts for metathesis reactions, Chemistry Today, Vol 24 nr 6, 2006.
Qian Zhigang, Zhao Zhenjiang, etc. Novel Chemically Synthesized Salicylate Derivative as an Effective Elicitor for Inducing the Biosynthesis of Plant Secondary Metabolites, Biotechnol. Prog. 2006, 22, 331-333.
Yufang Xu, Zhenjiang Zhao, Xuhong Qian, Zhigang Qian, Wenhong Tian, Jian-Jiang Zhong, Novel Unnatural Benzo-1,2,3-thiadiazole-7-carboxylate Elicitors of Taxoid Biosynthesis Journal of Agricultural Food Chemistry 54 (23): 8793-8798 2006.
Zhi-Gang Qian, Zhen-Jiang Zhao, Yufang Xu, Xuhong Qian and Jian-Jiang Zhong Novel synthetic 2,6-dichloroisonicotinate derivatives as effective elicitors for inducing the biosynthesis of plant secondary metabolites Applied Microbiology and Biotechnology, 71 (2): 164-167 2006.
Wei wang, Zhenjiang Zhao, Yufang Xu, Xuhong Qian, Zhanjiang Zhong,Efficient Induction of Ginsenoside Biosynthesis and Alteration of Ginsenoside Heterogeneity in Cell Cultures of Panax notoginseng by Using Chemically Synthesized 2-Hydroxyethyl Jasmonate, Applied Microbiology & Biotechnology, 70 (3): 298-307 2006.
Wei Wang, Zhenjiang Zhao, etc. Efficient elicatation of Ginsenoside biosynthesis in cell cultures of panax notoginseng by using self-chemically-synthesized Jasmonates, Biotechnology and Bioprocess Engineering 2005, 10: 162-165.
Zhi-Gang Qian, Zhen-Jiang Zhao, Yufang Xu, Xuhong Qian, Jian-Jiang Zhong,A novel synthetic fluoro-containing jasmonate derivative acts as a chemical inducing signal for plant secondary metabolism, Applied Microbiology and Biotechnology, 2005,68,98-103.
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