冀亚飞 - 华东理工大学

研究领域

1 绿色化学 2 杂环类药分子的设计与合成 3 药物制造过程的绿色工艺 4 有机合成中的区域与立体选择性控制研究

近期论文

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Zhang ZN, Huang JG, Zhai JJ, Guo Y, Ji YF*. Copper(II)-catalyzed oxidative esterification of substituted p-cresols under ligand- and additive-free conditions. Synlett 2015, 26, 2145–2150. Guo Y, Li YD, Chen C, Zhao JH, Liu HW, Liao DH, Ji YF*. A practical ligand-free copper(I) bromide-catalyzed fluoroalkoxylation of unactivated aryl bromides. Res. Chem. Intermediat. 2015-07-19, published online. DOI: 10.1007/s11164-015-2165-4. Huang JG , Guo Y, Li YD, Liu HW,* Liao DH, Ji YF*. Undecorated Cu(OAc)2-Catalyzed C(sp3)–C(sp3) Bond Formation Through a para-Hydroxyl Group-Triggered Remote Benzylic C(sp3)–H Bond Functionalization. Eur. J. Org. Chem. 2015, 5334–5338. Guo Y, Fan XM, Nie M, Liu HW, Liao DH, Pan XD,* Ji YF*. Practical ligand-free Cu-catalyzed short-chain alkoxylation of unactivated aryl bromides. Eur. J. Org. Chem. 2015, 4744–4755. Guo Y, Chen C, Liu HW,* Zhao JH, Zheng, YL, Ji YF*. A ligand-free, powerful and practical method for methoxylation of unactivated aryl bromides using CuCl/HCOOMe/MeONa/MeOH system. Res. Chem. Intermediat. 2015-01-8, published online. DOI: 10.1007/s11164-014-1917-x. Zhai JJ, Gu CH, Guo Y, Liao DH, Zhu DR, Ji YF*. One-pot synthesis of highly substituted 1H-pyrazole-5-carboxylates from 4-aryl-2,4-diketoesters and arylhydrazines. J. Heterocyclic Chem. 2015-06-18, published online. DOI 10.1002/jhet.2354. Huang JG, Guo Y, Jiang JA, Liu HW, Ji YF*. An eco-friendly Co(OAc)2-catalyzed aerobic oxidation of 4-benzylphenols into 4-hydroxybenzophenones. Res. Chem. Intermediat. 2014-10-10, published online. DOI: 10.1007/s11164-014-1801-8. Jiang JA, Chen C, Guo Y, Liao DH, Pan XD, Ji YF*. A highly efficient approach to vanillin starting from 4-cresol. Green Chem. 2014, 16, 2807–2814. Gu CH, Zhai JJ, Jiang JA, Liu HW, Wang L, Zhu DR, Ji YF*. An efficient one-pot synthesis of aryl-substituted 1-(thiazol-2-yl)-1H-pyrazole-3-carboxylates via a Hantzsch synthesis-Knorr reaction sequence. Chin. J. Chem. 2014, 32, 179–190. Jiang JA, Chen C, Huang JG, Liu HW, Cao S, Ji YF*. Cu(OAc)2-catalyzed remote benzylic C(sp3)–H oxyfunctionalization for C=O formation directed by the hindered para-hydroxyl group with ambient air as terminal oxidant under ligand- and additive-free conditions. Green Chem. 2014, 16, 1248–1254. Jiang JA, Du JL, Liao DH, Wang ZG, Ji YF*. Efficient Co(OAc)2-catalyzed aerobic oxidation of EWG-substituted 4-cresols to access 4-hydroxybenzaldehydes. Tetrahedron Lett. 2014, 55, 1406–1411. Zhai JJ, Gu CH, Jiang JA, Zhang SL, Liao DH, Wang L, Zhu DR, Ji YF*. A one- pot approach to ethyl 1,4,5-triaryl-1H-pyrazole-3-carboxylates via an improved Claisen condensation-Knorr reaction sequence. Chin. J. Chem. 2013, 31, 1526–1538. Jiang JA, Du JL, Zhang ZN, Zhai JJ, Ji YF*. An environmentally friendly and highly efficient Co(OAc)2-catalyzed aerobic oxidation to access 2,6-di-electron-donating group substituted 4-hydroxybenzaldehydes. Syn. Commun. 2014, 44, 1430–1440. Zhai JJ, Jiang JA, Zhang SL, Chen C, Liu HW, Liao DW, Ji YF*. Stereoselective or exclusive synthesis of ethyl Z-2-(2-substituted-thiazol-4-yl)pent-2-enoates from ethyl E/Z-2-(2-bromoacetyl)pent-2-enoate. Synlett 2013, 24, 1399–1404. Huang WB, Guo Y, Jiang JA, Pan XD, Liao DH, Ji YF*. An efficient strategy for protecting dihydroxyl groups of catechols. Synlett 2013, 24, 741–746. Jiang JA, Huang WB, Zhai JJ, Liu HW, Cai Q, Xu LX, Wang W, Ji YF*. “One-pot” synthesis of 4-substituted 1,5-diaryl-1H-pyrazole-3-carboxylates via lithium tert-butoxide-mediated sterically hindered Claisen condensation and Knorr reaction. Tetrahedron 2013, 69, 627–635. Jiang JA, Ji YF*. Alternative synthesis of apixaban (BMS-562247), an inhibitor of blood coagulation factor Xa. Syn. Commun. 2013, 43, 72–79. Jiang JA, Du CY, Gu CH, Ji YF*. “One-pot” synthesis of 4-substituted 1,5-diaryl-1H-pyrazole-3- carboxylic acids via a MeONa/LiCl-mediated sterically hindered Claisen condensation-Knorr reaction-hydrolysis sequence. Synlett 2012, 23, 2965–2968. Huang WB, Du CY, Jiang JA, Ji YF*. Concurrent synthesis of vanillin and isovanillin. Res. Chem. Intermediat. 2013, 39, 2849–2856. Ji YF*, Jiang JA, Liu HW, Liao DH, Wei XY. Practical preparation of trimethoprim: a classical antibacterial agent. Syn. Commun. 2013, 43, 1517–1522. Jiang JA, Zhai JJ, Yu XH, Teng X, Ji YF*. A practical synthesis of cefcapene pivoxil. Synthesis 2012, 44, 207–214. Yu CG, Zhang YN, Song AG, Ji YF*, Wang W*. Interplay of direct stereocontrol and dynamic kinetic resolution in a bifunctional amine thiourea catalyzed highly enantioselective cascade Michael–Michael reaction. Chem. Eur. J. 2011, 17, 770–774. Zhang YN, Yu CG, Ji YF*, Wang W*. Diastereo- and enantioselective organocatalytic direct conjugate addition of g-butenolide to chalcones. Chem. Asian J. 2010, 5, 1303–1306. Li H, Ji YF, Li J, Zhang SL, Yu CG, Wang W. Organocatalytic enantioselective Michael addition reactions of fluoromalonates with α,β-unsaturated aldehydes. Science China–Chemistry 2010, 53, 135–139.