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个人简介

吴黎川,1.2017-至今:广西大学医学院 2.2015.3-2017.3:广西大学化学化工学院,博士后 3.2008.9-2014.7:中国科学院动物研究所,博士 4.2004.9-2008.6:武汉大学,学士主讲课程1.《医学细胞生物学》 2.《生理学》主持(或参与)的主要科研项目1.广西自然科学基金青年科学基金,2017GXNSFBA198240,苦参碱衍生物LC-1逆转鼻咽癌细胞耐药的机制研究,2017/09-2020/09,10万元,在研,主持 2.广西自然科学基金面上项目,2018GXNSFAA050055,NPNT调控AKT促进肝癌上皮间充质转化(EMT)及转移的分子机制,2019/03-2022/02,12万元,在研,主持 3.广西科技厅强基计划项目,镉促进鼻咽癌细胞迁移与侵袭的实验研究,2018/01-2019/12,4万元,在研,主持 4.第三军医大学电磁辐射医学防护教育部重点实验室开放课题基金,2018/01-2019/12,4万元,在研,主持 5.广西师范大学药用资源化学与药物分子工程国家重点实验室开放课题基金,4万元,在研,主持 6.国家自然科学基金青年科学基金项目,61805049,低功率激光氧化损伤的乳腺肿瘤细胞调控免疫应答的研究,2019/01-2021/12,23万元,在研,参加 7.国家自然科学基金地区科学基金,21763004,电刺激控制联合释放Dex与NGF的三维神经电极材料的研究,2018/01-2021/12,38万元,在研,参加

研究领域

肿瘤发病机理及药理学研究

近期论文

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(1)YimingXu#,LichuanWu#,HaroonUrRashid,DewangJing,XiaoleLiang,HaodongWang,XuLiu,JunJiang,LishengWang*,PengXie*.Novelindolo-sophoridinicscaffoldasTopoIinhibitors:Design,synthesisandbiologicalevaluationasanticanceragents.EurJMedChem,156(2018)479-492. (2)LiZ#,LuoMY#,CaiB#,Haroon-Ur-Rashid,HuangMT,JiangJ,WangLS*,WuLC*.Design,synthesis,biologicalevaluationandstructure-activityrelationshipofsophoridinederivativesbearingpyrroleorindolescaffoldaspotentialantitumoragents.EurJMedChem,157(2018)665-682. (3)ZhengLi#,LichuanWu#,BinCai,MengyangLuo,MengtianHuang,HaroonUrRashid,YuwenYang,JunJiang*,LishengWang*.Design,synthesis,andbiologicalevaluationofthiomatrinederivativesaspotentialanticanceragents.MedChemRes,27(2018)1941-1955. (4)YimingXu#,LichuanWu#,HangDai,MingyanGao,HaroonUrRashid,HaodongWang,PengXie,XuLiu,JunJiang*,LishengWang*,Novel,β-UnsaturatedSophoridinicDerivatives:Design,Synthesis,MolecularDockingandAnti-CancerActivities,Molecules,2017,22(11),pii:E1967. (5)LichuanWu#,*,GuizhenWang#,JinruiWei#,NaHuang#,SenZhang,FangfangYang,MingLi,GuangbiaoZhou,LishengWang*,MatrineDerivativeYF-18InhibitsLungCancerCellProliferationandMigrationThroughDown-RegulatingSkp2,Oncotarget,2017,8(7),11729-11738. (6)JingfenLi#,DongLi#,YimingXu,ZhenboGuo,XuLiu,HuaYang,LichuanWu*,LishengWang*,Design,Synthesis,BiologicalEvaluation,andMolecularDockingofChalconeDerivativesasAnti-InflammatoryAgents,BioorgMedChemLett,2017,27(3):602-606. (7)LiheJiang#,LichuanWu#,FangfangYang#,NadinAlmosnid,XuLiu,JunJiang,ElliotAltman,LishengWang*,YingGao*,Synthesis,biologicalevaluationandmechanismstudiesofmatrinederivativesasanticanceragents,OncolLett,2017,14:3057-3064. (8)LichuanWu#,GuizhenWang#,ShuaibingLiu#,JinruiWei#,SenZhang,MingLi,GuangbiaoZhou*,LishengWang*,SynthesisandBiologicalEvaluationofMatrineDerivativesContainingBenzo-Alpha-PyroneStructureasPotentAnti-lungCancerAgents,SciRep,2016,6:35918. (9)LichuanWu#,ShuaibingLiu#,JinruiWei,DongLi,XuLiu,JianyiWang,LishengWang*,SynthesisandBiologicalEvaluationofMatrineDerivativesasAnti-HepatocellularCancerAgents,BioorgMedChemLett,2016,26(17):4267-4271. (10)JingfenLi#,YongYin#,LishengWang,PengyunLiang,MenghuaLi,XuLiu,LichuanWu*,HuaYang*,Synthesis,Characterization,andAnti-InflammatoryActivitiesofMethylSalicylateDerivativesBearingPiperazineMoiety,Molecules,2016,21(11),pii:E1544. (11)LichuanWu#,LiangxiaGuo#,YuehuiLiang,XuLiu,LiheJiang,LishengWang*,CurcuminSuppressesStem-LikeTraitsofLungCancerCellsviaInhibitingtheJAK2/STAT3SignalingPathway,OncolRep,2015,34(6):3311-3317. (12)XianjunYu#,MinjunYang#,BoZhou#,GuizhenWang#,YunchaoHuang#,LichuanWu#,XinCheng,ZheshengWen,JinyanHuang,YundongZhang,XiaohongGao,GaofengLi,ShuiwangHe,ZhaohuiGu,LiangMa,ChunmingPan,PingWang,HaobinChen,ZhipengHong,XiaoluWang,WenjingMao,XiaolongJin,HuiKang,ShutingChen,YongqiangZhu,WenyiGu,ZiLiu,HuiDong,LinweiTian,SaijuanChen*,YiCao*,ShengyueWang*,GuangbiaoZhou*,CharacterizationofSomaticMutationsinAirPollution-RelatedLungCancer,EBioMedicine,2015,2(6):583-590. (13)LichuanWu,ZheshengWen,YataoQiu,XiaoqinChen,HaobinChen,MingmingWei,ZiLiu,ShengJiang,GuangbiaoZhou*,LargazoleArrestsCellCycleatG1PhaseandTriggersProteasomalDegradationofE2F1inLungCancerCells,AcsMedChemLett,2013,4(10):921-926.

学术兼职

SCI期刊OncologyReports、OncologyLetters审稿人

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