娄向新 - 东华大学 - 化学化工与生物工程学院

研究领域

1.体细胞重编程及诱导型多能干细胞（iPS细胞）的定向分化。 2.干细胞与神经组织再生。 3.哺乳动物内耳发育与毛细胞的再生。

近期论文

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1.Xiangxin Lou*, Huihua Yuan, Jing Xie, Xianliu Wang, Liangliang Yang, Yanzhong Zhang. Growth factors have a protective effect on neomycin-induced hair cell loss. Cell Biology International, 2015, 39: 65-73. (IF2013=1.635) 2.Lin Gao, Tao Zhu, Guilin Xie, Xiangxin Lou, Shibao Li, Yan Zhou, Zhenxu Deng, Dechang Chu, Jiyu Lou, Dongshu Du. GABAA receptor overexpression in the lateral hypothalamic area attenuates gastric ischemia‑reperfusion injury in rats. Molecular Medicine Reports, 2015, 11(2):1057-1062. (IF2013=1.484) 3.Xiangxin Lou, Youyi Dong, Jing Xie, Xianliu Wang, Liangliang Yang, Masaaki Tokuda, Yanzhong Zhang. Comparing the cultivated cochlear cells derived from neonatal and adult mouse. Journal of translational medicine, 2014, 12(1): 150. (IF2013=3.991) 4.Dongshu Du, Xiangxin Lou*. Generation of induced pluripotent stem cells from neonatal mouse cochlear cells, Differentiation, 2014, 87: 127-133. ((IF2013= 2.836) 5.Xiangxin Lou*, Jing Xie, Xianliu Wang, Liangliang Yang, Yanzhong Zhang. Comparison of sphere-forming capabilities of the cochlear stem cells derived from apical, middle and basal turns of murine organ of Corti. Neuroscience Letters, 2014, 579: 1-6. (IF2013=2.055) 6.Huihua Yuan, Biyun Li, Kai Liang, Xiangxin Lou*, Yanzhong Zhang*. Regulating drug release from pH- and temperature-responsive electrospun CTS-g-PNIPAAm/poly (ethylene oxide) hydrogel nanofibers. Biomedical Materials, 2014, 9: 055001 (IF2013=2.992) 7.Min Bao，Ya-hui Zhou，Hui-hua Yuan，Xiang-xin Lou，Yan-zhong Zhang. Effect of Lysine on Ｒegulating Acidity of PLGA Nanofiber Degradation in vitro. Acta Polymerica Sinica, 2014, 5: 604-612. (IF2013=0.639) 8.Jing Xie, Xiangxin Lou, Liangliang Yang，Xianliu Wang, Yanzhong Zhang. Electrospun Nanofibers of Hydroxyapatite / Collagen / Chitosan Promote Osteogenic Differentiation of BMSCs. Journal of Donghua University (English Editon ) , 2014, 05: 649-653. (EI) 9.Liangliang Yang，Xianliu Wang, Jing Xie, Xiang-xin Lou, Yanzhong, Zhang. pH-Compensation Effect of Lysine on the Acidic Degradation of Electrospun Poly ( lactide-co-glycolide) Fibers in PBS. Journal of Donghua University ( English Editon ) , 2014, 04: 525-529. (EI) 10.Xian-liu, Wang, Liangliang Yang, Jing, Xie, Xiang-xin Lou, Yanzhong, Zhang. Fabrication of Dex-Loaded Shape Memory Polymer Based Composite Nanofibers for Potential Bone Tissue Engineering. , 2014, 05: 709-713. (EI) 11.Xiang-Xin Lou, Takayuki Nakagawa, Koji Nishimura, Hiroe Ohnishi, Norio Yamamoto, Tatsunori Sakamoto, Juichi Ito. Reprogramming of mouse cochlear cells by transcription factors to generate induced pluripotent stem cells. Cell Reprogram, 2013, 15(6): 514-519. (IF2013=2.744) 12.Xiang-Xin Lou, Takayuki Nakagawa, Hiroe Ohnishi, Koji Nishimura, Juichi Ito. Otospheres derived from neonatal mouse cochleae retain the progenitor cell phenotype after ex vivo expansions. Neuroscience Letters, 2013, 534: 18–23. (IF2013=2.055) 13.Youyi Dong, Li Sui, Fuminori Yamaguchi, Kazuyo Kamitori, Yuko Hirata, Akram Hossain, Chisato Noguchi, Ayako Katagi, Miki Nishio, Akira Suzuki, Xiangxin Lou, Masaaki Tokuda. The expression of PTEN in the development of mouse cochlear lateral wall. Neuroscience, 2014, 258: 263-269. (IF2013=3.327) 14.Min Bao, Xiangxin Lou, Qihui Zhou, Wen Dong, Huihua Yuan, Yanzhong Zhang, Biomimetic fibrous scaffold of PDLLA-co-TMC with shape memory effect for bone tissue engineering, ACS applied materials & interface, 2014, 6(4): 2611-2621. (IF2013= 5.9) 15.Min Bao, Qihui Zhou, Wen Dong, Xiangxin Lou, and Yanzhong Zhang. Ultrasound-Modulated Shape Memory and Payload Release Effects in a Biodegradable Cylindrical Rod Made of Chitosan-Functionalized PLGA Microspheres. Biomacromolecules. 2013, 14(6): 1971-1979. (IF2013=5.788) 16.Birgit Mazurek†, Xiangxin Lou†, Heidi Olze, Heidemarie Haupt, Agnieszka J. Szczepek. In vitro protection of auditory hair cells by salicylate from the gentamicin-induced but not neomycin-induced cell loss. Neuroscience Letters, 2012, 506: 107–110. (IF2013=2.055) 17.Xiangxin Lou, Yan Zhang, Chonggang Yuan. Multipotent stem cells from the young rat inner ear. Neuroscience Letters, 2007, 416: 28-33. (IF2013=2.055) 18.Xianxin Lou Yuan Chong-gang. Prospect of stem cells in the treatment of hearing loss. Chinese Journal of Clinical Rehabilitation, 2006, 10(33): 190-192. 19.董文, 包敏, 李碧云, 袁卉华, 娄向新, 张彦中. 含石墨烯的聚乳酸复合纳米纤维的制备及细胞相容性. 功能高分子学报 2014, 27(2): 147-156. 20.娄向新，袁卉华，包敏，张彦中. 模拟干细胞生长微环境以促进间充质干细胞的扩增. 中国细胞生物学报 2013, 35(11)：1681-1688.