徐中其 - 东华大学 - 化学化工与生物工程学院

研究领域

主要工作围绕毛细管电泳(Capillary Electrophoresis,CE)分离分析技术开展应用基础研究,以及探究在线富集技术提高方法灵敏度,发表在国际著名分析化学主流期刊 Anal. Chem., Electrophoresis, J. Chromatogr. A, Talanta, Biomicrofluidics的研究论文可参见: http://www.researcherid.com/rid/D-1023-2010.目前开展以下内容的研究工作. (1) 手性药物的毛细管电泳拆分技术 (2) 环境水体中典型抗生素的分析 (3) 复杂人体液中神经递质,氨基酸和生物活性胺类的分离分析

近期论文

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[1] Zhongqi Xu*, Aimei Li, Yongle Wang, Zhilong Chen, Takeshi Hirokawa, Pressure-assisted electrokinetic injection stacking for verteporfin drug to achieve highly sensitive enantioseparation and detection in artificial urine by capillary electrophoresis, J. Chromatogr. A 1355, 284-290 (2014). [2]李爱梅,黄茁,卢文平,徐中其*,基于毛细管电泳技术对水体中四环素类抗生素的基质效应及高灵敏分析方法研究,色谱 32, 897-903 (2014). [3]杨娇美,任杰,刘慧青,王永乐,徐中其*,神经递质类相关物质的毛细管电泳分离及在实际尿液中的检测,高等学校化学学报34, 2699-2703 (2013). [4] Xiaoxue Ye, Satomi Mori, Zhongqi Xu, Shinjiro Hayakawa, Takeshi Hirokawa, DNA aggregation and cleavage in CGE induced by high electric field in aqueous solution accompanying electrokinetic sample injection, Electrophoresis 34, 3155-3162 (2013). [5] Xiaoxue Ye, Satomi Mori, Mihoro Yamada, Junji Inoue, Zhongqi Xu*, Takeshi Hirokawa, Electrokinetic supercharging preconcentration prior to CGE analysis of DNA: sensitivity depends on buffer viscosity and electrode configuration, Electrophoresis 34, 583-589 (2013). [6] 徐中其*, 刘慧青,微流体芯片电泳技术对人血清蛋白的快速分离, 分析化学 40, 1118-1122 (2012). [7] Zhongqi Xu, Kouji Kawahito, Xiaoxue Ye, Andrei R. Timerbaev, Takeshi Hirokawa, Electrokinetic supercharging with a system-induced terminator and an optimized capillary versus electrode configuration for parts-per-trillion detection of rare-earth elements in CZE, Electrophoresis 32, 1195-1200 (2011). [8] Zhongqi Xu, Kentaro Nakamura, Andrei R. Timerbaev, Takeshi Hirokawa, Another Approach toward over 100 000-Fold Sensitivity Increase in Capillary Electrophoresis: Electrokinetic Supercharging with Optimized Sample Injection, Anal. Chem. 83, 398-401 (2011). [9] Zhongqi Xu, Noboru Okabe, Akihiro Arai, Takeshi Hirokawa, Investigation of the pH gradient formation and cathodic drift in microchip isoelectric focusing with imaged UV detection, Electrophoresis 31, 3558-3565 (2010). [10] Zhongqi Xu, Kenji Murata, Akihiro Arai, Takeshi Hirokawa, Band-broadening suppressed effect in long turned geometry channel and high-sensitive analysis of DNA sample by using floating electrokinetic supercharging on a microchip, Biomicrofluidics 4, 014108 (2010). [11] Zhongqi Xu, Jiro Okada, Andrei R. Timerbaev, Takeshi Hirokawa, Sensitive profiling of biogenic amines in urine using CE with transient isotachophoretic preconcentration, J. Sep. Sci. 32, 4143-4147 (2009). [12] Zhongqi Xu, Eiji Koshimidzu, Takeshi Hirokawa, Electrokinetic sample injection for high-sensitivity capillary zone electrophoresis (2): A study on improving the repeatability and applications in atmospheric pollutants, Electrophoresis 30, 3534-3539 (2009). [13] Zhongqi Xu, Toshiaki Esumi, Natsuki Ikuta, Takeshi Hirokawa, High-sensitive analysis of DNA fragments by capillary gel electrophoresis using transient isotachophoresis preconcentration and fluorescence detection, J. Chromatogr. A 1216, 3602-3605 (2009). [14] Zhongqi Xu, Andrei R. Timerbaev, Takeshi Hirokawa, High-sensitivity capillary and microchip electrophoresis using electrokinetic supercharging preconcentration: Insight into the stacking mechanism via computer modeling, J. Chromatogr. A 1216, 660-670 (2009).