个人简介

B.S. University of California, Davis, 1991 Ph.D. University of Oregon, 1996 Postdoctoral Associate, Univ., of Minnesota, 1996-1997 NIH Postdoctoral Fellow, University of Arizona, 1998-2000

研究领域

ANALYTICAL & PHYSICAL CHEMISTRY OF BIOLOGICAL SURFACES

The Conboy Group is actively developing novel analytical and bioanalytical techniques for the exploration of interfacial phenomena in biology and chemistry. We are currently pursuing research into the dynamics and structure of lipid membranes and the development of label-free methods for detecting protein and small-molecule adsorption to interfaces. Our laboratory uses a combination of nonlinear optical spectroscopies in conjunction with biological and electrochemical methods to achieve these objectives. Please peruse the selection of publications from our group listed below for more information about our research.

近期论文

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Anglin, T. C, Hao, L., Cooper, M. P., Chandler, K., Conboy, J. C., ??Free Energy and Entropy of Activation for Phospholipid Flip-Flop in Planar Supported Lipid Bilayers??, Journal of Physical Chemistry B, 2010, 114, 1903-1914 Nguyen, Trang T.; Conboy, John C, ??High-Throughput Screening of Drug-Lipid Membrane Interactions via Counter-Propagating Second Harmonic Generation Imaging??, Analytical Chemistry, 2011, 83, 5979-5988. Brown, K, Conboy, J. C., ??Electrostatic Induction of Lipid Asymmetry??, Journal of the American Chemical Society, 2011, 133, 8794-8797. Nguyen, Trang T.; Sly, Krystal L.; Conboy, John C., ??Comparison of the Energetics of Avidin, Streptavidin, NeutrAvidin, and Anti-Biotin Antibody Binding to Biotinylated Lipid Bilayer Examined by Second-Harmonic Generation??, Analytical Chemistry, 2012, 84, 201-208. Sly, Krystal L.; Nguyen, Trang T; Conboy, John C., "s surface second harmonic imaging" Opt. Express, 2012, 20, 21953-21967. Liu, J.; Brown, Krystal L.; Conboy, J. C., ??The effect of cholesterol on the intrinsic rate of lipid flip-flop as measured by sum-frequency vibrational spectroscopy??, Faraday Discussions, 2013, 161 (Lipid and Membrane Biophysics), 45-61. Brown, K, Conboy, J. C., ??Lipid Flip-?Flop in Binary Membranes Composed of Phosphatidylserine and Phosphatidylcholine??, Journal of Physical Chemistry B., 2013, 117, 15041-15050. Sly, Krystal L.; Mok, S.-W; Conboy, John C., "nd Harmonic Correlation Spectroscopy: A Method for Determining Surface Binding Kinetics and Thermodynamics" Analytical Chemistry, 2013, 85,8429-8435. Allhusen, John S.; Conboy John C., ??Preparation and Characterization of Conductive and Transparent Ruthenium Dioxide Sol-Gel Films??, ACS Applied Materials and Interfaces, 2013, 5, 11683-11681. Sly, Krystal L.; Conboy, John C.; ??Determination of Multivalent Protein-?Ligand Binding Kinetics by Second-?Harmonic Correlation Spectroscopy??, Analytical Chemistry, 2014, ASAPmmed at the