陈玉欣 - 湖北工业大学 - 生物工程与食品学院

个人简介

2005.9-2009.6华中农业大学植物科学技术学院植物科学与技术专业学士 2009.9-2015.6武汉大学药学院生物化学与分子生物学专业硕博连读博士 2016.3-2017.8美国加州大学河滨分校分子，细胞和系统生物学系LabAssistant PI：ManuelaMartins-Green教授 2017.9-2019.5美国加州大学河滨分校生物医学科学系AssistantSpecialist PI：ChristianLytle教授 2019.7至今湖北工业大学讲师《中草药》杂志青年编委；MedicalScienceMonitor杂志审稿人。 1.项目“黄连品种复杂生态系统的功能特征及其与小檗碱生物合成的关系研究”（No.20103060101000166），武汉大学，2009-2011，主持。 2.项目“荷叶黄酮类化合物结构与功能的研究”（2010CBB02301），湖北省自然科学基金重点项目，2008-2010，参与。 3.项目“创新药物研究开发”（2011ZX09401-302），国家科技重大专项课题，2009-2010，参与。 4.项目“油菜菌核病综合防控技术研究与示范推广”（201103016），农业部行业专项，2011-2015，参与。 5.项目“Absorptivetransportofaminoacidsbytheratcolon”，美国国立卫生研究院（NIH），2017-2019，参与。专利 1.王有为，田俊，李慧博，班小泉，陈丽君，陈玉欣，马冰馨；一种莳萝子挥发油芳香防霉剂及其制备方法和用途，ZL201210379251.6，2013.10.9. 2.王有为，曾红，班小泉，陈玉欣，田俊，何敬胜，黄博；莳萝子挥发油防治阴道念珠菌病的用途，ZL201110086418.5，2012.4.7. 3.王有为，班小泉，何敬胜，黄博，曾红，田俊，陈玉欣；芳香新塔花挥发油制备方法及其对油菜菌核病的防治作用，ZL201010579993.4，2012.12.9. 4.王有为，班小泉，黄博，何敬胜，田俊，曾红，陈玉欣；莳萝子挥发油制备方法及其对油菜菌核病的防治作用，ZL201010579992.X，2012.12.9.

研究领域

1.氧化压力相关的疾病研究； 2.中药化学组分及药理学研究； 3.药物的肠道吸收、转运及代谢。

近期论文

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1.YuxinChen1,GaoZhou1,BingxinMa,JingTong,YouweiWang*.ActiveConstituentintheEthylAcetateExtractFractionofTerminaliaBelliricaFruitExhibitsAntioxidation,Antifibrosis,andPro-apoptosisCapabilitiesinVitro.OxidativeMedicineandCellularLongevity2019,ArticleID5176090. 2.YuxinChen,NeemaAdhami,ManuelaMartins-Green*.Biologicalmarkersofharmcanbedetectedinmiceexposedfortwomonthstolowdosesofthirdhandsmokeunderconditionsthatmimichumanexposure.FoodandChemicalToxicology2018,122:95-103. 3.YuxinChen,ZipingZhou,QiguiMo,GaoZhou,YouweiWang*.GallicAcidAttenuatesDimethylnitrosamine-InducedLiverFibrosisbyAlterationofSmadPhospho-IsoformSignalinginRats.BioMedResearchInternational2018,ArticleID1682743. 4.NeemaAdhami1,YuxinChen1,ManuelaMartins-Green*.Biomarkersofdiseasefoundinmiceafterexposuretothirdhandsmokeequivalenttothosefoundinhomesofsmokers.ClinicalScience2017,131:2409-2426.(1:Co-firstauthor) 5.YuxinChen,JingTong,LanlanGe,BingxinMa,JingshengHe,YouweiWang*.EthylacetatefractionofTerminaliabelliricafruitinhibitsrathepaticstellatecellproliferationandinducesapoptosis.IndustrialCropsandProducts2015,76:364-373. 6.YuxinChen1,HongZeng1,JunTian,XiaoquanBan,BingxinMa,YouweiWang*.Dill(AnethumgraveolensL.)seedessentialoilinducesCandidaalbicansapoptosisinametacaspase-dependentmanner.FungalBiology2014,118:394-401. 7.YuxinChen1,HongZeng1,JunTian,XiaoquanBan,BingxinMa,YouweiWang*.AntifungalmechanismofessentialoilfromAnethumgraveolensseedsagainstCandidaalbicans.JournalofMedicalMicrobiology2013,62:1175-1183. 8.YuxinChen,QiguiMo,BaiboXie,BingxinMa,XinyuZang,GaoZhou,LinyouCheng,JamesHuaZhou*,YouweiWang*.HepatoprotectiveactivityofYiganmingmuoralliquidagainstisoniazid/rifampicin-inducedliverinjuriesinrats.ChineseMedicine2018,9:165-178. 9.LanlanGe,WenhuiZhang,GaoZhou,BingxinMa,QiguiMo,YuxinChen,YouweiWang*.NinephenylethanoidglycosidesfromMagnoliaofficinalisvar.bilobafruitsandtheirprotectiveeffectsagainstfreeradical-inducedoxidativedamage.ScientificReports2017,7:45342. 10.BingxinMa,JingWang,JingTong,GaoZhou,YuxinChen,JingshengHe,YouweiWang*.ProtectiveeffectsofChaenomelesthibeticaextractagainstcarbontetrachloride-induceddamageviatheMAPK/Nrf2pathway.Food&Function2016,7(3):1492-1500. 11.BingxinMa,XiaoquanBan,JingshengHe,BoHuang,HongZeng,JunTian,YuxinChen,YouweiWang*.AntifungalactivityofZiziphoraclinopodioidesLam.essentialoilagainstSclerotiniasclerotiorumonrapeseedplants(BrassicacampestrisL.).CropProtection2016,89:289-295. 12.JingTong,XinchengYao,HongZeng,GaoZhou,YuxinChen,BingxinMa,YouweiWang*.HepatoprotectiveactivityofflavonoidsfromCichoriumglandulosumseedsinvitroandinvivocarbontetrachloride-inducedhepatotoxicity.JournalofEthnopharmacology2015,174:355-363. 13.BingxinMa,XiaoquanBan,BoHuang,JingshengHe,JunTian,HongZeng,YuxinChen,YouweiWang*.InterferenceandmechanismofdillseedessentialoilandcontributionofcarvoneandlimoneneinpreventingSclerotiniarotofrapeseed.PloSOne2015,10(7):e0131733. 14.JunTian,YuxinChen,BingxinMa,JingshengHe,JingTong,YouweiWang*.DroserapeltataSmithvar.lunata(Buch.-Ham.)C.B.Clarkeasafeasiblesourceofplumbagin:phytochemicalanalysisandantifungalactivityassay.WorldJournalofMicrobiologyandBiotechnology2014,30:737-745. 15.BoHuang,YuxinChen,BingxinMa,GaoZhou,JingTong,JingshengHe,YouweiWang*.ProtectiveeffectofCichoriumglandulosumseedsfromultravioletB-induceddamageinratlivermitochondria.Food&Function2014,5:869-875. 16.GaoZhou,YuxinChen,SongLiu,XingchengYao,YouweiWang*.InvitroandinvivohepatoprotectiveandantioxidantactivityofethanolicextractfromMeconopsisintegrifolia(Maxim.)Franch.JournalofEthnopharmacology2013,148:664-670. 17.XinchengYao,LingZhu,YuxinChen,JunTian,YouweiWang*.Invivoandinvitroantioxidantactivityandα-glucosidase,α-amylaseinhibitoryeffectsofflavonoidsfromCichoriumglandulosumseeds.FoodChemistry2013,139:59-66. 18.BingxinMa1,LingZhu1,XiaoyanZang,YuxinChen,DongLi,YouweiWang*.Coptischinensisinflorescenceanditsmainalkaloidsprotectagainstultraviolet-B-inducedoxidativedamage.JournalofFunctionalFoods2013,5:1665-1672. 19.SongLiu,DongLi,BoHuang,YuxinChen,XiaocongLu,YouweiWang*.Inhibitionofpancreaticlipase,α-glucosidase,α-amylase,andhypolipidemiceffectsofthetotalflavonoidsfromNelumbonuciferaleaves.JournalofEthnopharmacology2013,149:263-269. 20.BoHuang,LingZhu,SongLiu,DongLi,YuxinChen,BingxinMa,YouweiWang*.Invitroandinvivoevaluationofinhibitionactivityoflotus(NelumbonuciferaGaertn.)leavesagainstultravioletB-inducedphototoxicity.JournalofPhotochemistryandPhotobiologyB:Biology2013,12:1-5. 21.LingZhu,BoHuang,XiaoquanBan,JingshengHe,YuxinChen,LiHan,YouweiWang*.Coptischinensisinflorescenceextractprotectionagainstultraviolet-B-inducedphototoxicity,andHPLC-MSanalysisofitschemicalcomposition.FoodandChemicalToxicology2012,50:2584-2588. 22.JunTian,XiaoquanBan,HongZeng,JingshengHe,YuxinChen,YouweiWang*.TheMechanismofAntifungalActionofEssentialOilfromDill(AnethumgraveolensL.)onAspergillusflavus.PloSOne2012,7(1):e30147. 23.XiaoquanBan,BoHuang,JingshengHe,YuxinChen,HongZeng,LiHan,YouweiWang*.InvitroandInvivoAntioxidantPropertiesofExtractsfromCoptischinensisInflorescence.PlantFoodsforHumanNutrition2011,66:175-180.